Test Price
2,800 AED✅ Home Collection Available
MT-TE Gene Mitochondrial Myopathy (Infantile, Transient) – NGS Test in UAE | 2800 AED | DNA Labs UAE
Executive Summary & Core Metrics
- Diagnostic Accuracy: 99.9% analytical sensitivity via ISO 9001:2015 certified next-generation sequencing (NGS) workflow.
- Premium Logistics: VIP mobile phlebotomy with hospital-grade temperature-controlled cold-chain home collection, available daily from 8 AM to 11 PM.
- Clinical Oversight: Post-test telephonic consultation with a Consultant Medical Genetics for result interpretation and pedigree context.
- Insurance Facilitation: Direct coverage verification via WhatsApp at +971 54 548 8731 prior to sample collection.
Test Overview & Methodology
This advanced NGS assay performs full-gene sequencing of the MT-TE mitochondrial gene to identify pathogenic variants associated with infantile transient mitochondrial myopathy. The condition presents in neonates with cardiac arrhythmias, profound hypotonia, and respiratory distress. Early molecular confirmation enables timely intervention and informed family counselling. The assay is conducted exclusively at DNA Labs UAE using a validated NGS pipeline with orthogonal confirmation of all clinically significant variants.
| Feature | DNA Labs UAE – MT-TE NGS Assay | Standard Genetic Panel Alternative |
|---|---|---|
| Precision | Targeted MT-TE full-gene sequencing via NGS – 99.9% analytical sensitivity | Broad panel may underrepresent mitochondrial tRNA genes; lower resolution for rare MT-TE alleles |
| Methodology | Next-Generation Sequencing (NGS) with orthogonal variant confirmation; ISO 9001:2015 certified laboratory | Often limited to Sanger sequencing or targeted hotspot panels without ISO certification in UAE |
| Speed | 3–4 weeks for definitive clinical report | 4–8 weeks; repeat testing frequently required due to incomplete coverage |
| Home Collection | Included – VIP mobile phlebotomy with hospital-grade cold-chain, 8 AM–11 PM daily | Clinic-only or outsourced courier without integrated cold-chain quality assurance |
Physician Insight & Safety Protocols
“As a consultant medical geneticist, I recognise the profound uncertainty families face when a newborn presents with unexplained hypotonia or cardiac instability. The MT-TE NGS assay offers a targeted molecular window into infantile transient mitochondrial myopathy, yet it must always be integrated with a comprehensive clinical assessment, metabolic workup, and echocardiographic evaluation. A genetic variant alone does not constitute a diagnosis without phenotypic correlation. Genetic counselling before and after testing is essential to ensure informed decision-making and accurate risk communication for future family planning.” – Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
Do not discontinue, initiate, or alter any prescribed medication or nutritional supplementation for your infant without direct consultation with the managing paediatrician and metabolic specialist.
Safety Exclusion Criteria & Emergency Red Flags
- Exclusion: Active febrile illness or suspected systemic infection – defer home collection until clinical resolution.
- Exclusion: Infant on anticoagulant therapy requires explicit physician clearance and coordinated paediatric phlebotomy protocol.
- Emergency Red Flags: Seek immediate emergency care if the infant develops acute respiratory distress, severe floppiness (hypotonia), cyanosis, or loss of consciousness before or after sample collection.
- Mandatory genetic counselling must be completed prior to specimen collection to document informed consent and construct a three-generation pedigree.
Patient FAQ & Clinical Guidance
1. What is the MT-TE gene test and why is it relevant for my infant’s heart or muscle weakness?
This NGS assay directly sequences the MT-TE mitochondrial gene to detect pathogenic variants responsible for infantile transient mitochondrial myopathy. The condition typically presents with cardiac arrhythmia, hypotonia, poor feeding, and respiratory difficulty in the first weeks of life. Early molecular diagnosis guides metabolic management, cardiac monitoring, and family counselling.
2. How is the sample collected, and when will I receive the results?
A standard peripheral blood sample (2–3 mL) is collected via VIP mobile phlebotomy at your residence between 8 AM and 11 PM daily, using hospital-grade cold-chain transport. Alternatively, a dried blood spot on an FTA card can be used. The definitive clinical report is delivered within 3–4 weeks, followed by a telephonic consultation with our Consultant Medical Genetics to interpret the findings.
3. Is this test accredited under UAE healthcare regulations, and can my insurance cover the cost?
Yes. The assay is performed at DNA Labs UAE, which adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 concerning health ICT. Clinical safety follows Federal Decree-Law No. 4 of 2016 on Medical Liability. The laboratory is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139). Direct insurance billing verification is available via WhatsApp at +971 54 548 8731 prior to scheduling.
4. What does the turnaround time include, and is genetic counselling mandatory?
The 3–4 week turnaround encompasses full NGS sequencing, bioinformatic analysis, orthogonal variant confirmation, and Consultant Medical Genetics review. Yes, genetic counselling is mandatory before sample collection to ensure informed consent, accurate pedigree documentation, and to discuss potential implications for family members. A post-result counselling session is also provided.
UAE Regulatory & Data Privacy Adherence
This service operates in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent protocols adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. The laboratory is accredited to ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139). All genetic data is encrypted, access-restricted, and processed exclusively within UAE jurisdiction.
Clinical & Logistical Metadata
| Test Name | MT-TE Gene Mitochondrial Myopathy (Infantile, Transient) – NGS Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Whole blood (peripheral venipuncture) or dried blood spot (FTA card) |
| Methodology Used | Next-Generation Sequencing (NGS) with orthogonal variant confirmation |
| ICD-10-CM Code | G71.3 |
| LOINC Code | 81261-8 |
| DHA Facility License & Laboratory Address | DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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