Test Price
2,800 AED✅ Home Collection Available
MT-CO2 Gene (Cytochrome c Oxidase 2 Deficiency) Genetic Test in UAE | 2,800 AED | DHA Licensed
Executive Summary & Core Metrics
This advanced diagnostic test provides definitive molecular analysis of the MT-CO2 gene using high-throughput Next-Generation Sequencing (NGS) for the identification of pathogenic variants underlying cytochrome c oxidase deficiency. The service includes ISO-accredited processing, temperature-controlled sample logistics, and integrated post-test clinical guidance by a Consultant Medical Geneticist.
- Accuracy Guarantee: 99.9% Analytical Sensitivity for SNVs & Indels via ISO 15189 Compliant NGS.
- Premium Logistics: Paid VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Comprehensive telephonic post-test session with expert result interpretation and family planning consultation.
- Insurance: Direct billing verification available via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The MT-CO2 Gene NGS Test detects pathogenic variants in the mitochondrial genome responsible for complex IV (cytochrome c oxidase) deficiency, a severe neuro-metabolic disorder. This advanced sequencing panel enables precise diagnosis of Leigh syndrome and other progressive neurological conditions associated with mitochondrial dysfunction.
| Feature | Our MT-CO2 NGS Test | Closest Alternative (Sanger) |
|---|---|---|
| Technology | Next-Generation Sequencing (NGS) | Sanger Sequencing (single-exon focus) |
| Coverage | Entire MT-CO2 coding region + mtDNA variants | Targeted hotspot regions only |
| Analytical Sensitivity | >99.9% for SNVs & indels | ~95% (limited by read depth) |
| Turnaround Time | 3 to 4 Weeks | 4 to 6 Weeks |
| Sample Types | Blood, Extracted DNA, FTA Card | Blood only |
| Price | 2,800 AED | 2,100 – 2,500 AED (limited scope) |
| Genetic Counselling | Included (pre- & post-test) | Often not included |
Physician Insight & Safety Protocols
"As a Consultant Medical Genetics, I deeply understand the complex clinical journey associated with diagnosing mitochondrial disorders. This MT-CO2 NGS panel offers a definitive molecular confirmation that is critical for guiding prognosis, treatment, and family counseling. It is vital that positive results are integrated with biochemical, neuroimaging, and clinical data within a multidisciplinary care framework."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication & Clinical Advisory
Do not discontinue or alter any prescribed medication, metabolic therapy, or nutritional supplement without direct consultation with your managing specialist. Mitochondrial supportive therapies require precise biochemical monitoring and should only be adjusted under expert supervision to prevent metabolic decompensation.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Active febrile illness, recent blood transfusion (< 4 weeks), severe anemia (Hb < 8 g/dL), or patient inability to provide informed consent.
- Emergency Red Flags: Sudden vision loss, unexplained seizures or status epilepticus, acute respiratory failure, severe metabolic acidosis, or rapid neurological deterioration. Seek immediate emergency medical care if any of these occur before or during the testing window.
- Special Populations: For pregnant minors, specific provisions under Federal Decree-Law No. 4 of 2016 on Medical Liability apply; guardian consent is mandatory.
Patient FAQ & Clinical Guidance
1. What is the MT-CO2 cytochrome c oxidase 2 deficiency NGS test used for?
It is a high-precision genetic test that sequences the entire MT-CO2 gene to identify pathogenic mutations underlying mitochondrial complex IV deficiency. This test aids in the definitive diagnosis of Leigh syndrome and other progressive neurodegenerative disorders linked to mitochondrial DNA dysfunction.
2. How accurate is NGS for detecting MT-CO2 mutations?
Our NGS platform achieves >99.9% analytical sensitivity and specificity for single nucleotide variants (SNVs) and small insertions or deletions. This makes it the gold standard for comprehensive mitochondrial gene analysis when compared to traditional Sanger sequencing.
3. What does the 2,800 AED price include and can I use insurance?
The fixed price covers a professional home sample collection by a qualified phlebotomist, full NGS sequencing and bioinformatic analysis, a detailed clinical report, and one comprehensive post-test genetic counseling session with a specialist. Direct insurance billing can be verified prior to booking via WhatsApp at +971 54 548 8731.
4. How should I prepare for the sample collection?
No special preparation is required for the blood draw. However, it is important to inform the phlebotomist of any history of bleeding disorders or if you are currently taking anticoagulant medication. The sample collection process is rapid and can be performed in the comfort of your home.
UAE Regulatory & Data Privacy Adherence
Your Data Security & Clinical Compliance Framework
- DHA Facility License Number: 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
- Strict adherence to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) for all genomic and health data handling.
- Full compliance with Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields for digital health records.
- Clinical safety and patient consent protocols governed by Federal Decree-Law No. 4 of 2016 on Medical Liability.
- ISO 15189:2022 & ISO 9001:2015 Certified – Cert: INT/EGQ/2509DA/3139.
Clinical & Logistical Metadata
| Test Name | MT-CO2 Gene (Cytochrome c Oxidase 2 Deficiency) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Blood, Extracted DNA, FTA Card | Paid VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection Available (Daily 8 AM – 11 PM) |
| Methodology Used | Next-Generation Sequencing (NGS) – Full Gene Coverage |
| ICD-10-CM Code | E88.49 |
| LOINC Code | 91716-1 |
| DHA Facility License & Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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All reports reviewed by DHA-Certified physicians