Test Price
2,800 AED✅ Home Collection Available
MRE11 Gene Ataxia-Telangiectasia-Like Disorder Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
Comprehensive NGS-Based Genetic Analysis
- Diagnostic Sensitivity: 99.9% via Next-Generation Sequencing (NGS) with ISO 9001:2015 certified processing.
- Turnaround Time: 3–4 weeks from sample receipt to clinical report.
- Sample Collection: Standard peripheral blood draw; VIP mobile phlebotomy and temperature-controlled home collection available daily 8 AM–11 PM across the UAE.
- Post-Test Guidance: Dedicated telephonic session with a clinical geneticist to interpret results and coordinate care.
- Insurance Support: Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This next-generation sequencing (NGS) assay targets the MRE11 gene to identify pathogenic variants associated with Ataxia-Telangiectasia-Like Disorder (ATLD), a rare autosomal recessive condition characterized by progressive cerebellar ataxia, oculomotor apraxia, and heightened cancer predisposition. The test achieves 99.9% analytical sensitivity and specificity, enabling early diagnosis and informed surveillance strategies.
| Feature | Our Test | Closest Alternative |
|---|---|---|
| Precision | 99.9% analytical sensitivity (NGS) | ~95% sensitivity (Sanger sequencing) |
| Method | Next-Generation Sequencing (NGS) – whole gene coverage | Targeted gene panel by PCR |
| Turnaround Time | 3–4 weeks | 4–6 weeks |
| Sample Instructions | Single EDTA blood draw (3–5 mL); no special preparation required | May require saliva or buccal swab; lower DNA yield |
Physician Insight & Safety Protocols
“The MRE11 gene test provides a definitive molecular diagnosis for Ataxia-Telangiectasia-Like Disorder, a condition that often mimics other cerebellar ataxias. Understanding the genetic basis enables tailored cancer surveillance and family counseling. However, these results must be integrated with the patient’s full clinical picture—neurological examination, family history, and imaging—before any management decisions are made. Never alter treatment without direct consultation with your specialist.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Advisory & Medication Caution
Do not discontinue or modify any prescribed medications without prior discussion with your physician. Genetic test results are informational and do not replace clinical judgment.
Exclusion Criteria & ER Red Flags
- Exclusion: Active systemic infection, severe coagulopathy, or inability to provide informed consent (surrogate decision-maker required).
- Exclusion: Recent blood transfusion within 2 weeks may affect germline DNA purity; reschedule if clinically feasible.
- ER Red Flag: Seek immediate medical attention for sudden-onset gait deterioration, double vision, severe dysphagia, or unexplained seizures.
Patient FAQ & Clinical Guidance
1. What is the MRE11 gene test, and why is it recommended?
The MRE11 gene test is a next-generation sequencing assay that detects pathogenic variants in the MRE11 gene, confirming a diagnosis of Ataxia-Telangiectasia-Like Disorder (ATLD). It is recommended for individuals presenting with progressive cerebellar ataxia, oculomotor apraxia, and a family history suggestive of autosomal recessive inheritance, as well as for cancer risk stratification.
2. How is the sample collected, and is home collection available?
A single peripheral blood draw (3–5 mL in an EDTA tube) is required. Our DHA-licensed phlebotomists provide VIP mobile phlebotomy and temperature-controlled cold-chain home collection across the UAE, daily from 8 AM to 11 PM. This ensures sample integrity without the need for hospital visits.
3. What should I expect after receiving my results?
You will receive a detailed clinical report and a dedicated telephonic post-test counseling session with a consultant medical geneticist. The specialist will explain the findings, integrate them with your personal and family history, and coordinate multidisciplinary referrals to neurology, genetics, or oncology if indicated.
4. How long does it take to get results?
The turnaround time is 3–4 weeks from the date the sample reaches our ISO-accredited laboratory. Your physician will receive the report electronically as soon as it is completed.
5. Can I get the test if I have had a blood transfusion recently?
If you have received a blood transfusion within the last 2 weeks, the test may be affected by donor DNA contamination. We recommend waiting until at least 2 weeks after transfusion, or discuss with your physician whether an alternative sample type (e.g., buccal swab) is appropriate.
UAE Regulatory & Data Privacy Adherence
Trust & Compliance Framework
- Data Protection: Fully compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Clinical Safety: Patient consent and medical liability adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Accreditations: ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139). All laboratory processes are validated under DHA and MOHAP standards.
- Facility License: DHA Facility License No. 1143, Dubai Healthcare City.
Clinical & Logistical Metadata
| Test Name | MRE11 Gene Ataxia-Telangiectasia-Like Disorder Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Peripheral whole blood (EDTA), extracted DNA, or dried blood spot (FTA card) |
| Methodology Used | Next-Generation Sequencing (NGS) – full gene coverage |
| ICD-10-CM Code | G11.3 (Cerebellar ataxia with defective DNA repair) |
| LOINC Code | 82939-0 (MRE11 gene targeted mutation analysis in Blood or Tissue by NGS) |
| DHA Facility License & Address | License No. 1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
Corporate Lab Branding: DNA Labs UAE
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All reports reviewed by DHA-Certified physicians