Test Price
4,000 AED✅ Home Collection Available
MPZ Full Length Gene Sequence Analysis (Charcot‑Marie‑Tooth Disease) in UAE | 4000 AED | 2026 DHA Guidelines
تحليل تسلسل الجين الكامل لجين MPZ (داء شاركو‑ماري‑توث) في الإمارات | 4000 درهم | معتمد من هيئة الصحة بدبي
Executive Summary
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing (ISO 9001:2015, Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: Paid Hospital‑Grade Home Collection via ISO Certified Cold‑Chain Home Collection & VIP Mobile Phlebotomy (8 AM – 11 PM).
- Clinical Guidance: Telephonic Post‑Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
ملخص تنفيذي
- ضمان الدقة: حساسية تشخيصية بنسبة 99.9% عبر معمل معتمد وفق معيار ISO 9001:2015.
- خدمة منزلية متميزة: سحب عينات بمعايير سلسلة التبريد المعتمدة ووحدة سحب متنقلة (VIP Mobile Phlebotomy) طوال اليوم.
- استشارة طبية هاتفية بعد النتائج لتفسير التحليل.
- التحقق المباشر من التأمين الصحي عبر واتساب.
Test Overview
This single‑gene Sanger sequencing test decodes the entire MPZ (myelin protein zero) gene with nucleotide‑level resolution, pinpointing pathogenic variants responsible for Charcot‑Marie‑Tooth disease type 1B – the most common inherited peripheral neuropathy. يحدد هذا التحليل الطفرات المسببة في جين MPZ بدقة متناهية، مما يدعم التشخيص الجيني الجزيئي والتخطيط العائلي.
| Feature | Our Test (Sanger Sequencing) | Closest Alternative (NGS Panel) |
|---|---|---|
| Precision | Gold‑standard single‑base accuracy; reads every exon & splice site | High but may miss deep intronic or low‑coverage regions |
| Method | Sanger Sequencing (bidirectional) | Next‑Generation Sequencing (multigene panel) |
| Turnaround Time | 3‑4 weeks (express option available) | 4‑6 weeks (often with secondary confirmatory step) |
| Clinical Utility | Definitive diagnosis of CMT1B; variant of uncertain significance clarified | Broad screening; incidental findings may complicate interpretation |
Physician Insight & Safety Protocol
“As a DHA‑licensed physician, I emphasize that this genetic result is a powerful diagnostic tool, but it must be interpreted alongside your clinical history, nerve conduction studies, and family pedigree. A negative MPZ sequence does not exclude other forms of Charcot‑Marie‑Tooth disease; further evaluation by a neurologist or medical geneticist is essential for comprehensive care.”
— Dr. Prabhakar Reddy, DHA License: 61713011
DO NOT discontinue any prescribed medication (e.g., analgesics, anticonvulsants for neuropathic pain, physiotherapy regimens) without consulting your physician. Genetic test results do not replace ongoing symptomatic management.
Exclusion Criteria & ER Red Flags
Exclusion Criteria
- Active systemic infection (fever >38.5°C)
- Severe coagulopathy or current anticoagulant therapy that cannot be temporarily held (for invasive samples)
- Uncontrolled psychiatric condition impairing informed consent
- Pregnancy‑related contraindications for amniocentesis/CVS (evaluated by fetal medicine specialist)
Seek Emergency Care If
- Sudden, rapidly progressive muscle weakness or paralysis
- Respiratory difficulty or choking sensation
- Loss of bladder or bowel control
- Severe, unrelenting neuropathic pain unresponsive to usual medication
Frequently Asked Questions
What exactly does MPZ full‑length gene sequencing detect?
This test detects single‑nucleotide variants, small insertions/deletions, and splice‑site mutations across the entire MPZ gene, providing a definitive molecular diagnosis of Charcot‑Marie‑Tooth disease type 1B with near‑100% analytical sensitivity for coding regions.
يفحص هذا التحليل جميع طفرات جين MPZ، بما في ذلك تغيرات النوكليوتيدات المفردة والحذف والإدراج الصغير، مما يمنح تشخيصًا جزيئيًا مؤكدًا لداء شاركو‑ماري‑توث 1B.
How should I prepare before sample collection?
No fasting or special preparation is required for peripheral blood; for amniotic fluid or chorionic villus samples, a dedicated fetal medicine consultation will provide you with precise pre‑procedural instructions and consent paperwork.
لا يتطلب تحليل الدم أي صيام أو تحضير خاص؛ أما عينات السائل الأمنيوسي أو الزغابات المشيمية فستتلقى إرشادات دقيقة من أخصائي طب الجنين.
Can I use my health insurance for this test?
Many UAE insurers cover genetic testing when medically indicated; our team will verify your policy directly via WhatsApp +971 54 548 8731 and provide a pre‑authorization estimate before you proceed, so you face no unexpected costs.
تغطي العديد من شركات التأمين في الإمارات الفحوصات الجينية عند وجود دواعي طبية؛ سيتولى فريقنا التحقق من تغطيتك عبر واتساب وتقديم تقدير مسبق للتكاليف.
Regulatory Compliance: This is performed in strict adherence to Federal Decree‑Law No. 41 of 2024 (Art. 87) regarding medical laboratories and patient data protection; UAE CDS Law 2026 mandates written informed consent from a parent/legal guardian for genetic testing of minors; All personal health information is handled per UAE PDPL and ISO 27001 standards. Facility License: 9834453. DHA/MOHAP standard nomenclature applied. يتوافق هذا الفحص تمامًا مع القانون الاتحادي رقم 41 لسنة 2024 وقانون حماية البيانات الشخصية في دولة الإمارات.
© 2026 Precision Genetic Diagnostics – All rights reserved. DHA‑Approved Content.
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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