Test Price
2,800 AED✅ Home Collection Available
MMP21 Gene Heterotaxy, Visceral Type 7 – Genetic Test in UAE | 2,800 AED | DHA Compliant
Executive Summary & Core Metrics
- ✓ 99.9% Diagnostic Sensitivity via ISO‑Accredited NGS Processing
- ✓ VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection (Available daily 8 AM‑11 PM)
- ✓ Post‑Test Telephonic Clinical Guidance by DHA‑Licensed Consultant Medical Geneticist
- ✓ Direct Insurance Billing Verification via WhatsApp: +971 54 548 8731
Clinical Confidence Indicators
- Test Price: 2,800 AED (all‑inclusive, no hidden fees)
- Turnaround Time: 3–4 weeks from sample receipt
- Sample Types: 2 mL whole blood (EDTA), 1 μg extracted DNA, or one drop of blood on an FTA card
- Methodology: High‑depth Next‑Generation Sequencing (NGS) – full coding region ± 20 bp splice junctions
Test Overview & Methodology
This focused Next‑Generation Sequencing (NGS) test analyzes the full coding region of the MMP21 gene to diagnose heterotaxy visceral type 7, a congenital laterality disorder that disturbs the normal left‑right patterning of thoracic and abdominal organs. Performed in a DHA‑licensed, ISO 9001:2015 molecular laboratory, the assay delivers clinically actionable results within 3‑4 weeks using a small volume of whole blood, extracted DNA, or a dried blood spot on an FTA card.
Pathogenic variants in MMP21 disrupt extracellular matrix remodeling during embryogenesis, leading to abnormal organ positioning. Early diagnosis is critical for managing associated cardiac, splenic, and gastrointestinal anomalies.
| Feature | Our Test (DNA Labs UAE) | Alternative (Single‑Site Genotyping) |
|---|---|---|
| Method | High‑depth NGS (full gene sequencing) | Targeted mutation analysis (common variants only) |
| Coverage | All exons ± 20 bp splice junctions | Limited to known familial variants |
| Turnaround | 3–4 weeks | 4–6 weeks |
| Sensitivity | >99.9% for single‑nucleotide variants & small indels | Variable; may miss novel mutations |
All analyses performed at DNA Labs UAE, Dubai Healthcare City.
Physician Insight & Safety Protocols
“A pathogenic variant in MMP21 does not always predict exact clinical severity; I therefore interpret each result in the context of the child’s echocardiogram, splenic function, and visceral arrangement—and never offer a prognosis solely from the genetic report. If the test indicates a diagnosis of heterotaxy visceral type 7, prompt multidisciplinary follow‑up with paediatric cardiology and immunology is life‑saving.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA License No. 9294403
Advisory: Medication Management
Do not discontinue any prescribed medication without consulting your treating physician. Genetic testing does not replace medical management; blood‑thinning, cardiovascular, or immunosuppressive therapies must continue as directed.
Exclusion Criteria & Emergency Red Flags
Sample Collection Exclusion:
- Blood transfusion within the last 4 weeks (may dilute donor DNA)
- Active haematological malignancy with peripheral blast crisis
- Inability to obtain informed consent from legal guardian (mandatory for minors)
Clinical Red Flags – Seek Emergency Care if:
- New‑onset cyanosis (blue skin/lips) or severe respiratory distress
- Signs of acute intestinal obstruction (bilious vomiting, rigid abdomen)
- Overwhelming sepsis in an asplenic/polysplenic patient
Patient FAQ & Clinical Guidance
1. How quickly can I receive the MMP21 NGS test result in Dubai or Abu Dhabi?
You will receive the fully interpreted genetic report within 3 to 4 weeks from sample receipt, thanks to our in‑country DHA‑licensed NGS workflow and dedicated bioinformatics pipeline.
2. Does this test require a paediatric genetic counselling session before blood collection?
Yes, a pre‑genetic counselling session is mandatory to draw a detailed pedigree and ensure the family understands the implications of a positive MMP21 result.
3. Can I use my UAE health insurance to cover the 2,800 AED cost?
Most major UAE insurers cover diagnostic genetic testing for congenital anomalies; we provide direct billing verification via WhatsApp at +971 54 548 8731—simply send your policy details before booking.
4. Is home collection available for this test?
Yes, for venous whole blood (EDTA) samples our VIP Mobile Phlebotomy service operates daily 8 AM‑11 PM with temperature‑controlled cold‑chain logistics. Dried blood spot cards can be submitted via secure medical courier.
UAE Regulatory & Data Privacy Adherence
Legal & Compliance Framework
- Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) – governs all patient genetic data handling.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – regulates digital health records and telemedicine.
- Federal Decree‑Law No. 4 of 2016 on Medical Liability – ensures clinical safety and informed consent for genetic testing.
- All samples processed at DNA Labs UAE under DHA Facility License No. 1143, Dubai Healthcare City.
Clinical & Logistical Metadata
| Test Name | MMP21 Gene Heterotaxy, Visceral Type 7 (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 – 4 weeks |
| Sample Type / Matrix | Whole blood (EDTA), extracted DNA, or dried blood spot (FTA card) |
| Methodology Used | High‑depth Next‑Generation Sequencing (NGS) – full coding region ± 20 bp splice junctions |
| ICD-10-CM Code | Q89.3 (Situs inversus / heterotaxy) |
| LOINC Code | 21669-6 (DNA sequencing) |
| DHA Facility License & Laboratory Address | License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians