Test Price
2,800 AEDโ Home Collection Available
MMP1 Gene (Epidermolysis Bullosa Dystrophica Modifier) Genetic Test in UAE
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy (08:00 โ 23:00).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by a DHA-licensed Consultant Medical Genetics.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Price: 2,800 AED | Turnaround Time: 3 โ 4 Weeks | Sample: Whole Blood, Dried Blood Spot, or Extracted DNA
Test Overview & Methodology
The MMP1 gene modifier test uses next-generation sequencing to detect variants that influence severity in autosomal recessive dystrophic epidermolysis bullosa (RDEB). This test aids dermatologists, geneticists, and pediatricians in diagnosis, carrier screening, and prognosis. Full gene coverage including promoter, exonic, and intronic regions is achieved using an Illumina platform with bioinformatic annotation.
| Feature | Our MMP1 NGS Test | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Precision | 99.9% sensitivity (full gene coverage) | 95% sensitivity; limited to known hot spots |
| Methodology | Next-Generation Sequencing (Illumina platform, bioinformatic annotation) | PCR-based Sanger sequencing of exons only |
| Turnaround Time | 3 โ 4 Weeks | 6 โ 8 Weeks |
| Sample Options | Whole blood, dried blood spot (FTA card), extracted DNA | Whole blood only |
| Post-test Support | Telephonic clinical guidance + genetic counsellor session included | Often not included |
Physician Insight & Safety Protocols
โThe MMP1 gene modifier test provides critical prognostic information for families affected by recessive dystrophic epidermolysis bullosa. However, results must be interpreted alongside clinical phenotype, pedigree analysis, and blistering distribution to guide management. Pre-test and post-test genetic counselling by a qualified specialist is essential to ensure informed decision-making and accurate risk assessment.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory on Medication Continuity
โ ๏ธ Do not discontinue any prescribed medication or therapy without consulting your treating physician. Genetic test results are not a replacement for ongoing dermatological or medical care.
Exclusion Criteria & Emergency Red Flags
- Active systemic infection or acute febrile illness may require postponement of blood collection.
- Severe anaemia (Hb <7 g/dL) must be medically stabilised before venipuncture.
- Emergency Red Flags: New extensive blistering, skin tears with signs of sepsis (fever, chills, confusion), or sudden inability to eat due to oral involvement require immediate hospital attendance.
Patient FAQ & Clinical Guidance
1. What is the MMP1 gene modifier test for epidermolysis bullosa?
This genetic test sequences the MMP1 gene using NGS to identify variants that modify the severity of autosomal recessive dystrophic epidermolysis bullosa, helping predict skin fragility and blistering outcomes. A pre-test genetic counselling session with pedigree analysis is required before sample collection.
2. How long does it take to get results and what is the cost?
Results are delivered within 3 to 4 weeks at a price of 2,800 AED, including pre-test genetic counselling and post-test telephonic interpretation by a DHA-licensed consultant.
3. Who should consider this test?
Individuals with a family history of dystrophic epidermolysis bullosa, those seeking carrier status, or patients with an unclear diagnosis should consult a dermatologist or clinical geneticist to determine whether this test is appropriate.
4. Is home sample collection available for this test?
Yes, VIP Mobile Phlebotomy and temperature-controlled cold-chain home collection are available daily from 8 AM to 11 PM for whole blood, dried blood spot, or extracted DNA specimens. A prior genetic counselling session is mandatory before scheduling collection.
UAE Regulatory & Data Privacy Adherence
This genetic test strictly adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical testing safety and patient consent follow Federal Decree-Law No. 4 of 2016 on Medical Liability. All samples are processed in our ISO 9001:2015 certified laboratory (Cert: INT/EGQ/2509DA/3139) under the supervision of DNA Labs UAE, Dubai Healthcare City.
Clinical & Logistical Metadata
| Test Name | MMP1 Gene (Epidermolysis Bullosa Dystrophica Modifier) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 โ 4 Weeks |
| Sample Type / Matrix | Whole Blood, Dried Blood Spot (FTA Card), Extracted DNA |
| Methodology Used | Next-Generation Sequencing (Illumina Platform, Bioinformatic Annotation) |
| ICD-10-CM Code | Q81.2 |
| LOINC Code | 81247-9 |
| DHA Facility License & Laboratory Address | License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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