Test Price
2,800 AED✅ Home Collection Available
MLH1 Gene Genetic Test for Muir-Torre Syndrome in UAE | 2,800 AED | DHA Licensed Facility 1143
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp: +971 54 548 8731
Test Overview & Methodology
The MLH1 Genetic Test analyses the entire coding region of the MLH1 gene for pathogenic variants linked to Muir-Torre syndrome and Lynch syndrome, a hereditary cancer predisposition. This comprehensive next-generation sequencing (NGS) assay detects single nucleotide variants, insertions/deletions, and copy number variations with high sensitivity and specificity.
| Feature | Our Test (MLH1 NGS) | Alternative (Single-Gene Sanger) |
|---|---|---|
| Precision | >99.9% sensitivity & specificity | ~95% sensitivity; limited to point mutations |
| Method | Next-Generation Sequencing (NGS) with CNV analysis | Sanger sequencing of selected exons only |
| Turnaround | 3-4 weeks | 5-8 weeks |
Physician Insight & Safety Protocols
"Understanding your genetic blueprint is a powerful step toward proactive health. The MLH1 test result must be interpreted within the full context of your clinical history and family pedigree. I encourage you to review these findings with a qualified oncologist or genetic counsellor for a truly personalized care plan."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory on Medication Continuity
Do not discontinue any prescribed medication without consulting your doctor. Genetic test results inform risk assessment but do not replace ongoing medical treatment. Always follow your physician's advice.
Exclusion Criteria & Emergency Red Flags
- Exclusion: This test is not a substitute for urgent oncology evaluation. Do not delay cancer screening if you have active symptoms.
- Exclusion: Minors require documented consent under UAE Federal Decree-Law No. 4 of 2016 on Medical Liability and a mandatory genetic counselling session.
- ER Red Flags: Seek immediate medical attention if you experience sudden unexplained bleeding, severe abdominal pain, rapid skin lesion changes, or neurological symptoms.
Patient FAQ & Clinical Guidance
1. What does the MLH1 gene reveal and who should consider it?
MLH1 mutations disrupt DNA mismatch repair, raising lifelong risks for colorectal, endometrial, and sebaceous skin cancers – ideal for individuals with a strong family history or Muir-Torre syndrome suspicion.
2. How is the sample collected and what preparation is required?
Our DHA-licensed phlebotomist collects a small blood sample at your home after a brief genetic counselling session. No special preparation is needed; the VIP Mobile Phlebotomy service operates daily from 8 AM to 11 PM.
3. When will I receive my results and what happens next?
Results are securely delivered within 3-4 weeks, accompanied by a telephonic interpretation session with a clinical expert for actionable guidance.
UAE Regulatory & Data Privacy Adherence
Our laboratory operates in full compliance with UAE federal laws governing genetic testing, data protection, and healthcare practice:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – ensures encrypted reporting and secure data handling.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – governs electronic health records and telemedicine.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – establishes informed consent and clinical safety standards for genetic testing.
- ISO 9001:2015 Certified – Quality Management System (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | MLH1 Gene Genetic Test (Muir-Torre Syndrome / Lynch Syndrome) |
| Price (AED) | 2,800 |
| Turnaround Time | 3-4 weeks |
| Sample Type / Matrix | Peripheral whole blood (3-5 mL in EDTA tube) – VIP Mobile Phlebotomy Home Collection available |
| Methodology Used | Next-Generation Sequencing (NGS) with CNV analysis |
| ICD-10-CM Code | Z15.89, Z80.0, Z12.11 |
| LOINC Code | 82533-7 |
| DHA Facility License & Address | License #1143 | DNA Labs UAE | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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ISMS 27001:2022
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All reports reviewed by DHA-Certified physicians