Test Price
2,800 AED✅ Home Collection Available
MKS1 Gene (Meckel Syndrome Type 1) Genetic Test in UAE | 2,800 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection – Available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance – interpretation support by our clinical genetics team.
- Insurance: Direct Billing Verification – send policy details via WhatsApp to +971 54 548 8731.
Test Overview & Methodology
This advanced Next Generation Sequencing (NGS) test analyzes the entire MKS1 gene, including all exons and splice sites, to identify pathogenic variants causing Meckel syndrome type 1 – a rare autosomal recessive ciliopathy affecting the kidneys, liver, and central nervous system. Definitive molecular confirmation supports family planning, prenatal diagnosis, and clinical management.
| Feature | Our Test (MKS1 NGS) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Methodology | Full-gene Next Generation Sequencing (NGS), coverage of all exons & splice sites | Single-gene Sanger sequencing, may miss deep intronic/copy number variants |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
| Price | 2,800 AED | 3,500–4,000 AED |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
“This test provides high-confidence molecular diagnosis for Meckel syndrome type 1, granting families critical answers. However, genetic variants must be interpreted in the full clinical context, including prenatal imaging and family history. A negative result does not exclude all ciliopathies; genetic counselling is essential before and after testing.”
Clinical Exclusion Criteria & Emergency Red Flags
- Exclusion: Individuals unable to provide informed consent, or minors lacking legal guardian consent (in compliance with Federal Decree-Law No. 4 of 2016 on Medical Liability).
- Exclusion: Patients with known confounding haematological disorders that may compromise DNA extraction quality; alternative sample arrangements must be discussed.
- ER Red Flag: If the patient (especially a child) develops acute respiratory distress, seizures, severe dehydration or signs of acute kidney injury (oliguria, facial oedema), seek immediate emergency care irrespective of test status.
Patient FAQ & Clinical Guidance
1. What is the MKS1 gene test and who should consider it?
This test identifies pathogenic mutations in the MKS1 gene to confirm Meckel syndrome type 1, recommended for individuals with suggestive prenatal ultrasound findings or a family history of the condition.
2. What sample is required and how is the collection performed?
A blood sample, extracted DNA, or a single drop on an FTA card is collected via our DHA-licensed VIP Mobile Phlebotomy service with temperature-controlled cold-chain transport, available daily from 8 AM to 11 PM.
3. How long do results take, and what does the report include?
Results are delivered in 3–4 weeks. The report includes variant classification (zygosity), clinical interpretation, and a genetic counselling session to guide next steps.
4. Is genetic counselling mandatory before testing?
Yes. A pre-test genetic counselling session to draw a pedigree chart and discuss implications is required before sample collection. Please schedule via WhatsApp at +971 54 548 8731.
UAE Regulatory & Data Privacy Adherence
- Data Privacy: This service operates in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Patient Consent & Safety: All clinical testing and informed consent procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Laboratory Accreditation: Licensed by Dubai Health Authority (DHA Facility License No. 1143) and ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | MKS1 Gene (Meckel Syndrome Type 1) Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Blood, extracted DNA, or FTA card specimen |
| Methodology Used | Next Generation Sequencing (NGS) – full gene coverage including exons and splice sites |
| ICD-10-CM Code | Q61.9 |
| LOINC Code | 81278-7 |
| DHA Facility License & Laboratory Address | License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE. Corporate Lab Branding: DNA Labs UAE |
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