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Test Price

2,500 AED

✅ Home Collection Available

MERRF Mutation Detection Test in UAE | 2500 AED | DHA Licensed

Executive Summary & Core Metrics

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited PCR Amplification.
  • Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Daily 8 AM – 11 PM).
  • Clinical Guidance: Telephonic Post-Test Genetic Interpretation by DHA-Licensed Consultant Medical Geneticist.
  • Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

The MERRF Mutation Detection Test is a targeted polymerase chain reaction (PCR) based analysis that identifies pathogenic variants in the mitochondrial DNA associated with myoclonic epilepsy with ragged red fibres syndrome. This confirms a clinical suspicion of mitochondrial encephalomyopathy and guides treatment planning.

Feature Our MERRF Test Closest Alternative
Precision Targeted MERRF gene PCR sequencing Whole mitochondrial genome NGS
Method PCR Amplification + Sanger validation Next-Generation Sequencing
Turnaround 10 working days 14–21 working days
Price (AED) 2500 ~5000+

Physician Insight & Safety Protocols

“MERRF mutation results must be interpreted alongside neurological history, EEG, and metabolic assays. A negative finding does not rule out other mitochondrial disorders, and every positive result should prompt comprehensive genetic counselling. Clinical correlation is essential.”

Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Advisory: Medication Continuity

Do not discontinue prescribed anti-epileptic medication without consulting your doctor. Abrupt withdrawal may trigger severe seizures or status epilepticus.

Exclusion Criteria & Red Flags

  • Exclusion: Hemolyzed, clotted, or frozen blood sample; missing mandatory Genomics Clinical Information Requisition Form (Form 20); incorrect anticoagulant.
  • Emergency Red Flags: New-onset myoclonus, loss of consciousness, severe ataxia, or respiratory muscle weakness. Seek immediate medical attention.

Patient FAQ & Clinical Guidance

1. What does a positive MERRF mutation result mean?

A positive result identifies a known pathogenic MERRF gene variant associated with mitochondrial encephalomyopathy, meriting neurological correlation and family screening.

2. How is the blood sample collected and transported?

A certified DHA-licensed phlebotomist collects 4 mL of whole blood in an EDTA tube; the sample is shipped refrigerated (never frozen) with completed Form 20.

3. Can I stop my epilepsy medication before the test?

No, anti-epileptic drugs must never be discontinued without your physician's explicit approval, as abrupt cessation risks severe breakthrough seizures.

UAE Regulatory & Data Privacy Adherence

All patient data is processed in strict compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Genomic information is encrypted, access-restricted, and never shared without explicit consent.

ISO 9001:2015 Certified | Cert: INT/EGQ/2509DA/3139

Clinical & Logistical Metadata

Test Name MERRF Mutation Detection Test (Myoclonic Epilepsy with Ragged Red Fibers)
Price (AED) 2,500
Turnaround Time 10 working days
Sample Type / Matrix Peripheral whole blood (4 mL EDTA tube)
Methodology Used PCR Amplification + Sanger Validation
ICD-10-CM Code G71.3 (Mitochondrial myopathy, not elsewhere classified)
LOINC Code 83991-2 (MERRF mutation analysis)
DHA Facility License & Laboratory Address License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE

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All reports reviewed by DHA-Certified physicians