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Also known as: Myoclonic Epilepsy with Ragged Red Fibers Mutation Detection Test

Results: 10 working days Sample: Peripheral whole blood

Test Price

2,500 AED

โœ… Home Collection Available

๐Ÿ“‹ Results in 10 working days

MERRF Mutation Detection Test in UAE | 2500 AED | DHA Licensed

Executive Summary & Core Metrics

  • โœ“ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited PCR Amplification.
  • โœ“ Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Daily 8 AM โ€“ 11 PM).
  • โœ“ Clinical Guidance: Telephonic Post-Test Genetic Interpretation by DHA-Licensed Consultant Medical Geneticist.
  • โœ“ Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

The MERRF Mutation Detection Test is a targeted polymerase chain reaction (PCR) based analysis that identifies pathogenic variants in the mitochondrial DNA associated with myoclonic epilepsy with ragged red fibres syndrome. This confirms a clinical suspicion of mitochondrial encephalomyopathy and guides treatment planning.

Feature Our MERRF Test Closest Alternative
Precision Targeted MERRF gene PCR sequencing Whole mitochondrial genome NGS
Method PCR Amplification + Sanger validation Next-Generation Sequencing
Turnaround 10 working days 14โ€“21 working days
Price (AED) 2500 ~5000+

Physician Insight & Safety Protocols

โ€œMERRF mutation results must be interpreted alongside neurological history, EEG, and metabolic assays. A negative finding does not rule out other mitochondrial disorders, and every positive result should prompt comprehensive genetic counselling. Clinical correlation is essential.โ€

โ€” Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Advisory: Medication Continuity

Do not discontinue prescribed anti-epileptic medication without consulting your doctor. Abrupt withdrawal may trigger severe seizures or status epilepticus.

Exclusion Criteria & Red Flags

  • Exclusion: Hemolyzed, clotted, or frozen blood sample; missing mandatory Genomics Clinical Information Requisition Form (Form 20); incorrect anticoagulant.
  • Emergency Red Flags: New-onset myoclonus, loss of consciousness, severe ataxia, or respiratory muscle weakness. Seek immediate medical attention.

Patient FAQ & Clinical Guidance

1. What does a positive MERRF mutation result mean?

A positive result identifies a known pathogenic MERRF gene variant associated with mitochondrial encephalomyopathy, meriting neurological correlation and family screening.

2. How is the blood sample collected and transported?

A certified DHA-licensed phlebotomist collects 4 mL of whole blood in an EDTA tube; the sample is shipped refrigerated (never frozen) with completed Form 20.

3. Can I stop my epilepsy medication before the test?

No, anti-epileptic drugs must never be discontinued without your physician's explicit approval, as abrupt cessation risks severe breakthrough seizures.

UAE Regulatory & Data Privacy Adherence

All patient data is processed in strict compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Genomic information is encrypted, access-restricted, and never shared without explicit consent.

ISO 9001:2015 Certified | Cert: INT/EGQ/2509DA/3139

Clinical & Logistical Metadata

Test Name MERRF Mutation Detection Test (Myoclonic Epilepsy with Ragged Red Fibers)
Price (AED) 2,500
Turnaround Time 10 working days
Sample Type / Matrix Peripheral whole blood (4 mL EDTA tube)
Methodology Used PCR Amplification + Sanger Validation
ICD-10-CM Code G71.3 (Mitochondrial myopathy, not elsewhere classified)
LOINC Code 83991-2 (MERRF mutation analysis)
DHA Facility License & Laboratory Address License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE

ุฏุนู… ุซู†ุงุฆูŠ ุงู„ู„ุบุฉ ู…ุชุงุญ

ุงู„ุชุญู‚ู‚ ู…ู† ุงู„ุชุบุทูŠุฉ ุงู„ุชุฃู…ูŠู†ูŠุฉ

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ุชูˆู‚ู ุนู† ุงู„ุชุฎู…ูŠู†. ุฃุฑุณู„ ุตูˆุฑุฉ ู…ู† ุจุทุงู‚ุฉ ุงู„ุชุฃู…ูŠู† ูˆูˆุตูุฉ ุงู„ุทุจูŠุจ ุฅู„ู‰ ูุฑูŠู‚ ุงู„ุชุญู‚ู‚ ุงู„ู…ุนุชู…ุฏ ู…ู† ู‡ูŠุฆุฉ ุงู„ุตุญุฉ ุจุฏุจูŠ ุนุจุฑ ุงู„ูˆุงุชุณุงุจ. ุงุญุตู„ ุนู„ู‰ ุชุญุฏูŠุซ ุงู„ุญุงู„ุฉ ููŠ ุฏู‚ุงุฆู‚.

โœ… DHA Certified โœ… ISO 15189 โœ… HIPAA Compliant

Available in Arabic, English, Hindi & Urdu

Preparation Required

["No specific fasting required.", "Do not discontinue prescribed anti-epileptic medication without consulting your doctor."]

Medically Reviewed by Dr. Lina Osama Zaki Quteineh

All content reviewed by qualified professionals for accuracy.

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ISMS 27001:2022

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ISO Accredited

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HIPAA

All reports reviewed by DHA-Certified physicians