Test Price
2,800 AED✅ Home Collection Available
MED23 Gene Autosomal Recessive Intellectual Disability Type 18 (MRT18) Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
High-precision genetic test for MED23 gene mutations causing autosomal recessive intellectual disability type 18, utilizing Next-Generation Sequencing (NGS) with full gene coverage and deletion/duplication analysis.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic post-test clinical guidance in result interpretation by a DHA-licensed Consultant Medical Geneticist.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The MED23 gene test analyzes the entire coding region using Next-Generation Sequencing (NGS) on the Illumina® platform to detect pathogenic variants causing autosomal recessive intellectual disability type 18 (MRT18). This highly sensitive assay is essential for confirming clinical diagnosis, carrier screening, and guiding family planning decisions. The test also includes deletion/duplication analysis to identify copy number variations that may be missed by conventional Sanger sequencing.
| Feature | Our Test (DNA Labs UAE – DHA Licensed) | Closest Alternative (Overseas Referral Lab) |
|---|---|---|
| Methodology | Full-gene NGS (Illumina® platform) with deletion/duplication analysis | Targeted Sanger sequencing only (limited to known hotspots) |
| Turnaround Time | 3–4 weeks (fast-track available) | 6–8 weeks |
| UAE Regulatory Compliance | DHA Licensed Facility #1143; ISO 9001:2015; compliant with Federal Decree-Law No. 45 of 2021 (PDPL) and Federal Law No. 2 of 2019 | No UAE license; samples shipped abroad with uncertain data privacy |
| Genetic Counseling | Included pre- and post-test session with pedigree chart | Not provided |
Physician Insight & Safety Protocols
“As a Consultant Medical Geneticist (DHA Registration ID: 9294403) with extensive experience in neurodevelopmental disorders, I emphasize that a positive MED23 result must be correlated with detailed clinical phenotyping and neurodevelopmental assessments. This test provides molecular confirmation, but the full picture of the patient’s health requires a multidisciplinary approach. Genetic information empowers, but does not define, a person’s potential.” – Lina Osama Zaki Quteineh, Consultant Medical Genetics
Advisory for Patients and Families
Clinical Guidance
- Exclusion Criteria: This test is not intended for prenatal diagnosis of MRT18 without prior genetic counseling. Home collection is contraindicated if the patient is hemodynamically unstable or has acute neurological deterioration.
- Emergency Red Flags: Seek immediate emergency care if the patient develops new-onset seizures, loss of consciousness, or sudden worsening of intellectual/behavioral symptoms.
- Pediatric Consent: In compliance with Federal Decree-Law No. 4 of 2016 on Medical Liability, testing of minors requires written informed consent from both parents or legal guardians.
Patient Exclusion Notice
Contraindications for Home Collection
Mobile phlebotomy is not available for patients with severe coagulopathy, active infection at the venipuncture site, or those requiring continuous intravenous therapy. Such patients must arrange sample collection at the laboratory premises or an affiliated hospital.
Patient FAQ & Clinical Guidance
1. What does a positive MED23 mutation test mean for my child’s future?
A positive result confirms a diagnosis of autosomal recessive intellectual disability type 18, which typically presents with moderate to severe developmental delay and absence of speech. However, clinical course varies; early intervention with speech, physiotherapy, and specialized education can significantly improve quality of life. A genetic counselor will discuss individualized management options.
2. How accurate is this NGS test compared to older genetic methods?
Our NGS assay achieves >99.9% analytical sensitivity and specificity for single nucleotide variants and small indels in the MED23 gene. It also detects copy number variations missed by Sanger sequencing, providing a comprehensive molecular result. This advanced technology ensures that even rare mutations are identified with high confidence.
3. Is home sample collection reliable for DNA testing?
Yes, when performed by our DHA-certified phlebotomy team using ISO cold-chain transport, DNA integrity is fully preserved from whole blood or extracted DNA. The process is identical to hospital draw and offers the convenience of your home. Our courier service ensures temperature-controlled delivery to the laboratory within the required timeframe.
UAE Regulatory & Data Privacy Adherence
Your Privacy is Protected
This test is conducted in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted, access-controlled, and used solely for diagnostic and clinical purposes. No data is shared with third parties without explicit patient consent as required by UAE law.
Clinical & Logistical Metadata
| Test Name | MED23 Gene Autosomal Recessive Intellectual Disability Type 18 (MRT18) Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 weeks (fast-track available upon request) |
| Sample Type / Matrix | Whole blood (EDTA), extracted DNA, or FTA card |
| Methodology Used | Next-Generation Sequencing (NGS) – Illumina® platform with deletion/duplication analysis |
| ICD-10-CM Code | Q87.8 (Other specified congenital malformation syndromes) |
| LOINC Code | 93859-0 (MED23 gene full sequencing) |
| DHA Facility License & Laboratory Address | License #1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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