Test Price
2,800 AED✅ Home Collection Available
LTBP2 Gene Glaucoma Primary Type 3D Genetic Test in UAE
Executive Summary & Core Metrics
This genetic test delivers 99.9% diagnostic accuracy for detecting pathogenic mutations in the LTBP2 gene associated with primary congenital glaucoma and related ocular disorders. Tested through ISO-accredited processes with VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (available daily 8 AM–11 PM). Results include a post-test telephone consultation with a board‑certified medical geneticist for comprehensive interpretation. Direct insurance verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The LTBP2 gene provides instructions for a protein essential for ocular tissue integrity. Mutations can cause primary congenital glaucoma by disrupting the extracellular matrix, leading to elevated intraocular pressure and optic nerve damage. Our test uses Next‑Generation Sequencing (NGS) to fully sequence the LTBP2 gene, identifying single‑nucleotide variants, insertions, deletions, and copy‑number variations with exceptional sensitivity. The table below compares our assay with alternative approaches.
| Feature | Our Test | Closest Alternative |
|---|---|---|
| Diagnostic Sensitivity | 99.9% | 95–98% |
| Methodology | NGS (Full Gene Coverage) | Sanger Sequencing (Limited Regions) |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks |
Physician Insight & Safety Protocols
“As a consultant in medical genetics, I emphasise that a positive LTBP2 result indicates an increased risk for primary congenital glaucoma and necessitates tailored ophthalmic surveillance, but does not guarantee disease onset. A negative result lowers, but cannot eliminate, the probability that other genetic or environmental factors are involved. Continuous ophthalmologist follow‑up remains essential — your clinical context is the ultimate guide.” — Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Important Advisory
Do not discontinue any prescribed medication without consulting your treating physician. Always inform our healthcare team of all current medicines, supplements, or herbal remedies before the blood collection.
Exclusion Criteria & Emergency Red Flags
- Blood Collection Exclusion: Active infection at venipuncture site, severe anemia (Hb < 8 g/dL), or known coagulopathy unless cleared by a physician.
- Genetic Counseling Exclusion: Inability to provide informed consent; for minors, parental/legal guardian presence is mandatory as per UAE Federal Decree‑Law No. 4 of 2016 on Medical Liability.
- Seek Immediate Medical Care If You Experience: Sudden severe eye pain, abrupt vision loss, or seeing rainbow‑colored halos around lights — these may indicate acute glaucoma.
Patient FAQ & Clinical Guidance
1. What is the LTBP2 gene and its role in glaucoma?
The LTBP2 gene provides instructions for making a protein crucial for maintaining the structure of ocular tissues; mutations can cause primary congenital glaucoma by disrupting extracellular matrix integrity, leading to elevated intraocular pressure and optic nerve damage. Our NGS panel fully sequences this gene to identify pathogenic variants.
2. Why is NGS technology superior for this test?
NGS screens the entire LTBP2 gene simultaneously, detecting subtle mutations that older methods like Sanger sequencing often miss, ensuring higher diagnostic sensitivity and the ability to uncover rare variants that might otherwise go undetected.
3. How should I prepare for the home blood collection?
No fasting or medication changes are required; however, inform our phlebotomist of any anticoagulant use or bleeding disorders beforehand to tailor the procedure safely. Maintain hydration and provide a valid Emirates ID for verification. Our VIP mobile phlebotomy team operates 8 AM–11 PM daily.
UAE Regulatory & Data Privacy Adherence
Data Protection & Clinical Compliance
This genetic test is performed in full compliance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data are encrypted, access‑controlled, and retained only for the period necessary for clinical care and legal retention obligations. Our laboratory holds ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139), ensuring rigorous quality management and data security excellence. Clinical safety and patient consent adhere to Federal Decree‑Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | LTBP2 Gene Glaucoma Primary Type 3D Genetic Test (NGS Full Gene Sequencing) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks (21–28 calendar days) |
| Sample Type / Matrix | Peripheral whole blood – EDTA tube (3–5 ml) |
| Methodology Used | Next‑Generation Sequencing (NGS) – Full gene sequencing with copy‑number variation detection |
| ICD‑10‑CM Code | Q15.0 (Congenital glaucoma) |
| LOINC Code | 81247-9 (Master HL7 genetic test panel) |
| DHA Facility License & Laboratory Address | License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians