Test Price
2,800 AED✅ Home Collection Available
LAMB3 Gene Amelogenesis Imperfecta Type 1A Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
UAE Trusted Diagnostic Excellence
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified NGS Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (8 AM – 11 PM daily).
- Clinical Guidance: Telephonic Post-Test Clinical Interpretation Support by DHA-Licensed Specialists.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The LAMB3 NGS test screens for pathogenic variants in the LAMB3 gene, responsible for Junctional Epidermolysis Bullosa (JEB) with Amelogenesis Imperfecta Type 1A. It delivers a comprehensive mutational spectrum, enabling precise diagnosis, carrier detection, and reproductive risk assessment.
| Feature | Our Test | Closest Alternative |
|---|---|---|
| Method | NGS (Full Gene Sequencing) | Sanger Sequencing (Targeted) |
| Coverage | All coding regions & splice sites | Single or few exons only |
| Turnaround | 3–4 Weeks | 6–8 Weeks |
| Regulatory | DHA-MOHAP Approved, ISO Certified | Variable external labs |
Physician Insight & Safety Protocols
"Clinical correlation with dental and dermatological phenotypes is paramount. A positive LAMB3 result must be integrated with a detailed family pedigree, and patients should be referred to a multidisciplinary team including a pediatric dentist, clinical geneticist, and dermatologist. Genetic counseling before and after testing is essential to ensure informed decisions and appropriate follow-up."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory: Do Not Alter Medical Therapy Without Physician Guidance
This genetic test provides predisposition information and should not be used to discontinue or modify current medications, wound care, or clinical therapy. Always consult your healthcare provider before making any changes to your treatment plan.
Safety Exclusion Criteria & Red Flags
- Exclusion: Recent allogeneic bone marrow transplant (donor DNA may cause false negatives).
- Exclusion: Samples not collected by trained phlebotomist using sterile technique.
- Emergency Red Flag: New onset of widespread blistering, severe oral ulcerations, or respiratory distress in neonates — immediate emergency care.
Patient FAQ & Clinical Guidance
1. What is the primary clinical indication for the LAMB3 gene test?
The LAMB3 test identifies mutations causing junctional epidermolysis bullosa with enamel defects, enabling precise diagnosis and family screening. It is indicated for individuals with suspected JEB, unexplained enamel hypoplasia, or a positive family history.
2. How long does it take to receive results, and what does the report include?
Results are delivered within 3–4 weeks in a comprehensive PDF covering variant classification, zygosity, and clinical correlation. The report includes ACMG/AMP variant interpretation guidelines with DHA-compliant recommendations for follow-up.
3. Can children undergo this test, and what are the legal requirements in the UAE?
Testing of minors is permitted under the UAE Federal Law No. 3 of 2016 on Child Rights (Wadeema’s Law) and Federal Decree-Law No. 45 of 2021 on Personal Data Protection, provided the legal guardian gives informed consent after pre-counselling. Results for children are reported in a manner safeguarding their best interests and future autonomy.
UAE Regulatory & Data Privacy Adherence
Trusted Data Protection & Compliance Framework
All genetic testing procedures at DNA Labs UAE comply with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent follow Federal Decree-Law No. 4 of 2016 on Medical Liability. The laboratory is licensed by the Dubai Health Authority (DHA) under Facility License Number 1143 and operates under ISO 9001:2015 quality management systems.
Clinical & Logistical Metadata
| Test Name | LAMB3 Gene Amelogenesis Imperfecta Type 1A Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA) or FTA Card |
| Methodology Used | Next Generation Sequencing (NGS) – Full Gene Sequencing |
| ICD-10-CM Code | Q81.1, K00.5 |
| LOINC Code | 21663-3 |
| DHA Facility License & Laboratory Address | DHA License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians