Test Price
2,800 AED✅ Home Collection Available
KRT6A Gene Pachyonychia Congenita Type 3 Genetic Test in UAE – 2,800 AED – DHA-Licensed Molecular Diagnosis
Executive Summary & Core Metrics
- ✔ Accuracy Guarantee: 99.9 % diagnostic sensitivity via ISO-accredited next-generation sequencing.
- ✔ Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AM – 11 PM.
- ✔ Clinical Guidance: Telephonic post-test counselling with a DHA-licensed Consultant Medical Geneticist.
- ✔ Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The KRT6A NGS test detects pathogenic variants in the KRT6A gene responsible for pachyonychia congenita type 3, a rare autosomal-dominant genodermatosis characterised by nail hypertrophy, palmoplantar keratoderma, and oral leukokeratosis. This ISO‑certified assay employs full-gene next-generation sequencing on the Illumina® platform to deliver definitive molecular diagnosis with 99.9 % analytical sensitivity.
| Feature | Our Test (NGS) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Precision | 99.9 % analytical sensitivity; full coding region coverage | Limited to selected exons; may miss deep intronic variants |
| Method | Next-Generation Sequencing (Illumina® platform) | Capillary electrophoresis Sanger sequencing |
| Turnaround | 21 – 28 days | 28 – 42 days |
| Expert Review | DHA-licensed clinical geneticist report with variant classification | Often without genetic counselling interpretation |
Physician Insight & Safety Protocols
“As a DHA-licensed Consultant Medical Geneticist, I recommend correlating KRT6A sequencing results with a comprehensive three-generation pedigree and clinical examination. A negative finding does not exclude pachyonychia congenita type 3 if classic features are present, because mutations in KRT6B, KRT16, or KRT17 can produce overlapping phenotypes. Pre‑test and post‑test genetic counselling is mandatory for informed decision-making and risk communication.” – Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Advisory: Medication Continuity & Sample Collection
🚩 Important Clinical Advisory
Do not discontinue any prescribed medication without consulting your treating physician. Genetic testing is a diagnostic adjunct and does not replace current therapy or clinical monitoring. Inform your phlebotomist of all medications, including anticoagulants, before sample collection.
Exclusion Criteria & Emergency Red Flags
- Absolute: Inability to provide a peripheral whole-blood sample or extracted DNA due to a medical contraindication.
- Relative: Severe coagulopathy or current anticoagulant therapy that may complicate venipuncture – discuss with your physician before booking.
- Seek immediate emergency care if after sample collection you experience uncontrolled bleeding, an expanding haematoma at the puncture site, or signs of infection (redness, swelling, fever).
Patient FAQ & Clinical Guidance
1. What is the diagnostic accuracy of the KRT6A NGS test for pachyonychia congenita type 3?
Our validated NGS assay delivers 99.9 % analytical sensitivity and specificity for detecting KRT6A gene mutations using ISO‑certified protocols and Illumina sequencing chemistry. Clinical validation demonstrates a diagnostic yield exceeding 98 % in patients who meet the established diagnostic criteria for pachyonychia congenita type 3.
2. How is the sample collected and transported to your laboratory?
A trained phlebotomist collects 3–5 mL of peripheral whole blood in an EDTA tube at your home or office. The specimen is immediately placed in a temperature-controlled cold-chain container and couriered to our ISO-accredited laboratory. Our VIP Mobile Phlebotomy service operates daily from 8 AM to 11 PM across all UAE emirates.
3. What is the turnaround time and how will I receive my results?
Results are issued within 21 to 28 days from sample receipt. The final report includes variant-level interpretation classified according to ACMG/AMP guidelines, a clinical commentary by a DHA-licensed Consultant Medical Geneticist, and a secure electronic copy delivered via encrypted portal. A telephonic consultation is scheduled to discuss the findings and next steps.
UAE Regulatory & Data Privacy Adherence
🔒 Data Protection & Legal Compliance
This service operates in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted at rest and in transit, stored on DHA-approved infrastructure, and accessible only to authorised clinical personnel. Clinical safety and patient consent protocols follow Federal Decree-Law No. 4 of 2016 on Medical Liability. Results are released only after verified patient consent.
ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139) | DNA Labs UAE – DHA Facility License: 1143
Clinical & Logistical Metadata
| Test Name | KRT6A Gene Pachyonychia Congenita Type 3 Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 21 – 28 Days (3 – 4 Weeks) |
| Sample Type / Matrix | Peripheral Whole Blood (3–5 mL in EDTA tube) or Extracted DNA |
| Methodology Used | Next-Generation Sequencing (NGS) – Illumina® Platform |
| ICD-10-CM Code | Q84.4, Z84.0, Z15.89 |
| LOINC Code | 82939-0 |
| DHA Facility License & Laboratory Address | License: 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians