Test Price
2,800 AED✅ Home Collection Available
KIF5A Gene SPG10 Genetic Test in UAE – 2,800 AED
Executive Summary & Core Metrics
Accuracy Guarantee:
99.9% diagnostic sensitivity and specificity via ISO‑accredited NGS processing.
Premium Logistics:
VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection (available daily 8 AM–11 PM).
Clinical Guidance:
Complimentary telephonic post‑test result interpretation with a consultant medical geneticist.
Insurance & Billing:
Direct insurance verification via WhatsApp: +971 54 548 8731
Test Overview & Methodology
The KIF5A gene test identifies pathogenic variants causing autosomal dominant hereditary spastic paraplegia type 10 (SPG10) through high‑depth NGS sequencing of the entire coding region and flanking intronic boundaries.
| Feature | Our KIF5A SPG10 NGS Test | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Diagnostic Accuracy | 99.9% analytic sensitivity & specificity | >95%, limited to known point mutations |
| Methodology | Next‑Generation Sequencing (NGS), full gene coverage | Sanger sequencing, selected exons only |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks |
| Genetic Counseling Included | In‑depth pre‑ and post‑test session | Often not included |
| Price | 2,800 AED | 3,500 AED |
Physician Insight & Safety Protocols
“As a consultant in medical genetics, I stress that a positive KIF5A variant provides essential prognostic and family planning information; however, results must always be correlated with a thorough neurological examination and three‑generation family history. Never interpret genetic findings in isolation. Expert medical guidance is indispensable.” – Lina Osama Zaki Quteineh (Consultant Medical Genetics, DHA Registration ID: 9294403)
⚠️ Clinical Advisory
Do not discontinue any prescribed medication without consulting your doctor. Genetic testing is not a substitute for ongoing medical management.
Exclusion Criteria & Emergency Red Flags
- Individuals unable to provide informed consent; pregnant persons without prior genetic counseling.
- Phenotype unrelated to hereditary spastic paraplegia without a neurologist’s referral.
- ER Red Flags: Sudden severe leg weakness, loss of bladder/bowel control, or acute confusion – seek immediate emergency care.
Patient FAQ & Clinical Guidance
1. What is the KIF5A gene and how does it relate to SPG10?
The KIF5A gene encodes a kinesin motor protein critical for axonal transport in neurons. Pathogenic variants disrupt this transport, leading to progressive lower limb spasticity and weakness characteristic of hereditary spastic paraplegia type 10 (SPG10).
2. Who should consider this genetic test?
Individuals with progressive lower limb spasticity, a family history of hereditary spastic paraplegia, unexplained gait disturbances, or those undergoing pre‑conception carrier screening for SPG10. A referral from a neurologist or genetic counselor is recommended.
3. How accurate is the KIF5A SPG10 NGS test?
Our test achieves 99.9% analytic sensitivity and specificity for single‑nucleotide variants and small indels in the KIF5A gene. All clinically significant findings are confirmed by Sanger sequencing and reviewed by a consultant medical geneticist.
UAE Regulatory & Data Privacy Adherence
This diagnostic service complies with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data are handled under strict confidentiality and consent protocols as mandated by the Dubai Health Authority (DHA). ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | KIF5A Gene Sequencing (Hereditary Spastic Paraplegia Type 10) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (3–5 mL in EDTA tube) |
| Methodology Used | Next‑Generation Sequencing (NGS), whole gene coverage with 150‑bp paired‑end reads |
| ICD-10-CM Code | G11.4 (Hereditary spastic paraplegia) |
| LOINC Code | 95035-4 (KIF5A gene full sequencing in Blood or Tissue by NGS) |
| DHA Facility License & Laboratory Address | License No. 1143 – DNA Labs UAE Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians