Test Price
2,800 AEDโ Home Collection Available
KHDC3L Gene Sequencing for Recurrent Hydatidiform Mole Type 2 in Dubai, UAE
Executive Summary & Core Metrics
This advanced genetic test delivers 99.9% diagnostic sensitivity through ISO-accredited Next-Generation Sequencing (NGS) for detecting pathogenic variants in the KHDC3L gene linked to recurrent hydatidiform mole type 2. The analysis supports precise diagnosis, informed genetic counseling, and family planning decisions. Turnaround time is 3โ4 weeks from sample receipt. Direct billing verification is available via WhatsApp at +971 54 548 8731. VIP Mobile Phlebotomy and temperature-controlled cold-chain home collection are offered daily from 8 AM to 11 PM.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (daily 8 AM โ 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in Result Interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The KHDC3L gene test uses Next-Generation Sequencing (NGS) to comprehensively analyze the coding regions and splice junctions of the KHDC3L gene. This approach detects pathogenic variants responsible for recurrent hydatidiform mole type 2, a rare autosomal recessive reproductive disorder characterized by abnormal trophoblastic proliferation and failure of normal embryonic development. Early molecular diagnosis enables proactive reproductive counseling and management strategies.
| Feature | Our Test (NGS) | Alternative (Sanger Sequencing) |
|---|---|---|
| Precision | >99% sensitivity, whole gene coverage, including deep intronic regions | Limited to targeted exonic regions, lower comprehensive detection |
| Method | Next-Generation Sequencing (NGS) on Illumina platform | Sanger Sequencing (single exon or small region) |
| Turnaround Time | 3โ4 Weeks | 6โ8 Weeks |
Physician Insight & Safety Protocols
"As a Consultant Medical Genetics specialist, I emphasize that KHDC3L gene sequencing results must be interpreted within the full clinical context of the patient's obstetric history, serial beta-hCG levels, and pelvic ultrasound findings. A negative sequencing result reduces but does not eliminate the possibility of an underlying genetic etiology; a positive finding enables targeted reproductive planning, including preimplantation genetic testing and donor gamete options. Always review outcomes with a board-certified genetic counselor and a high-risk pregnancy specialist."
โ ๏ธ Advisory Pre-Test Consideration
Do not discontinue any prescribed medication, including iron supplements or hormonal therapy, without explicit instruction from your treating physician. This genetic test is a diagnostic adjunct for reproductive planning and does not replace routine prenatal surveillance or emergency obstetric care.
Exclusion Criteria & Emergency Red Flags
- Acute vaginal bleeding, severe lower abdominal pain, or signs suggestive of ectopic pregnancyโseek immediate emergency care before scheduling this test.
- Recent blood transfusion or allogeneic bone marrow transplant (within 4 weeks) may introduce donor DNA and compromise sequencing accuracy.
- Known active hydatidiform mole requires urgent clinical evacuation and histopathological evaluation; genetic testing is not a substitute for emergency management.
- If you experience sudden shortness of breath, chest tightness, or severe headache, call 998 immediately.
Patient FAQ & Clinical Guidance
1. What is the turnaround time for the KHDC3L gene test result?
Results are typically delivered within 3 to 4 weeks from sample receipt. The duration reflects rigorous NGS analysis, bioinformatics interpretation, and ISO-accredited validation steps performed at our Dubai Healthcare City laboratory.
2. Do I need to fast or prepare in any special way before sample collection?
No fasting or special preparation is required. The test accepts a standard peripheral blood draw, an extracted DNA sample, or a simple FTA card drop. Our VIP Mobile Phlebotomy team can collect the sample at your home between 8 AM and 11 PM daily.
3. Will my health insurance cover the cost of KHDC3L gene sequencing in the UAE?
Insurance coverage is policy-dependent. DNA Labs UAE offers direct billing verification via WhatsApp at +971 54 548 8731 to confirm pre-approval before sample collection. Contact us to check your specific plan.
4. How is the sample collected if I choose home phlebotomy?
A certified phlebotomist visits your residence within our service area, performs a standard venipuncture using sterile technique, and transports the specimen in a temperature-controlled cold chain directly to our ISO-accredited laboratory. The service is available daily from 8 AM to 11 PM.
5. Can this test detect all types of hydatidiform mole?
No. This test specifically detects pathogenic variants in the KHDC3L gene, which cause recurrent hydatidiform mole type 2 (familial). Other genetic forms and sporadic moles require different molecular analyses. Your genetic counselor will determine the most appropriate testing strategy based on your clinical history.
UAE Regulatory & Data Privacy Adherence
All genetic testing at DNA Labs UAE is conducted under the governance of the Dubai Health Authority (DHA Facility License 1143) and in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) for the collection, processing, and storage of genetic data. Clinical safety and patient consent protocols adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. Health information exchanged electronically is protected under Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Our laboratory holds ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139) and follows CAP/CLIA-equivalent quality standards for molecular diagnostics.
Clinical & Logistical Metadata
| Test Name | KHDC3L Gene Sequencing for Recurrent Hydatidiform Mole Type 2 |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA), Extracted DNA, or FTA Card |
| Methodology Used | Next-Generation Sequencing (NGS) on Illumina Platform |
| ICD-10-CM Code | O01.9 |
| LOINC Code | 82978-8 |
| DHA Facility License & Address | DHA License 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians