Test Price
2,800 AED✅ Home Collection Available
ISG15 Gene Immunodeficiency Type 38 Genetic Test in UAE | 2,800 AED | DNA Labs UAE
Executive Summary & Core Metrics
Executive Summary
Diagnose ISG15 deficiency with 99.9% diagnostic sensitivity via ISO‑certified NGS. Enjoy premium hospital‑grade home collection (8 AM‑11 PM) through our cold‑chain mobile phlebotomy team. Receive expert post‑test telephonic clinical guidance and instant insurance coverage verification via WhatsApp at +971 54 548 8731.
Core Metrics: 2,800 AED full‑gene sequencing, 3‑4 week turnaround, comprehensive exon/intron coverage, ISO 15189:2022 accredited molecular diagnostics laboratory.
Test Overview & Methodology
The ISG15 Gene Immunodeficiency Type 38 Genetic Test employs next‑generation sequencing (NGS) on the Illumina platform to achieve comprehensive coverage of all coding exons and flanking intronic regions of the ISG15 gene. This approach detects pathogenic variants associated with autosomal recessive immunodeficiency type 38, also known as Mendelian Susceptibility to Mycobacterial Disease (MSMD). The test is indicated for patients with unexplained mycobacterial infections, severe viral illnesses, and recurrent skin lesions.
| Feature | Our ISG15 NGS Test | Closest Alternative (Sanger Hotspot) |
|---|---|---|
| Methodology | Next‑Generation Sequencing (Illumina NovaSeq) – full exon/intron coverage | Sanger sequencing of select exons (2‑3 common mutations) |
| Analytical Sensitivity | 99.9% (variants >5% allele frequency) | ~80% (misses rare/novel mutations) |
| Turnaround Time | 3‑4 weeks | 4‑6 weeks |
| Price (AED) | 2,800 | ~1,500 (limited scope) |
Physician Insight & Safety Protocols
The ISG15‑mediated immunodeficiency represents a distinct subtype of primary immunodeficiency where genetic confirmation is essential for definitive diagnosis and family counseling. NGS‑based testing offers the necessary breadth to capture both common and novel variants across the gene. I advise all referring physicians to accompany genetic results with functional immunological assays and pedigree analysis for comprehensive patient management.
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory: Medication Continuation
Medication Warning
Do not modify or discontinue any prescribed antimicrobial or immunomodulatory regimen without explicit direction from your treating specialist. This diagnostic test complements, but does not replace, ongoing clinical supervision and therapeutic decision‑making.
Safety Exclusion Criteria & Emergency Red Flags
- Infants below 2 months of age require specific phlebotomy protocols.
- Presence of active febrile illness (≥38.5°C) within 24 hours prior to sampling.
- Documented bleeding disorder or severe thrombocytopenia lacking physician clearance.
- Seek emergency care if post‑collection symptoms include high fever, severe localized pain, or systemic indicators of sepsis.
Patient FAQ & Clinical Guidance
1. What is the ISG15 Gene Immunodeficiency Type 38 Genetic Test?
This advanced genetic test uses next‑generation sequencing to detect pathogenic variants in the ISG15 gene, diagnosing primary immunodeficiency type 38 with high precision. It provides full coverage of coding and non‑coding regions to identify both common and rare mutations.
2. How should I prepare for sample collection?
Our genetic counsellor will conduct a pre‑ telehealth session to review your clinical and family history, draw a pedigree, and explain all implications. No special dietary or medication preparation is required unless specifically instructed.
3. When will I receive my results and what post‑test support is available?
Results are delivered within 3–4 weeks through a secure portal, followed by a telephonic consultation with our clinical team to explain the findings and recommend next steps. Insurance coverage verification is available instantly via WhatsApp at +971 54 548 8731.
UAE Regulatory & Data Privacy Adherence
All genetic testing services at DNA Labs UAE are conducted in alignment with:
- Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) – ensuring your genetic information is processed under strict privacy safeguards.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – governing digital health data integrity.
- Federal Decree‑Law No. 4 of 2016 on Medical Liability – establishing clear clinical accountability frameworks.
Our laboratory operates under DHA Facility License No. 1143 and maintains ISO 15189:2022 accreditation for molecular genetic testing.
Clinical & Logistical Metadata
| Test Name | ISG15 Gene Immunodeficiency Type 38 Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Peripheral Whole Blood – VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection (Available daily from 8 AM to 11 PM) |
| Methodology Used | Next‑Generation Sequencing (NGS) – Illumina platform, full exon/intron coverage |
| ICD-10-CM Code | D84.8 |
| LOINC Code | 81265-3 |
| DHA Facility License & Laboratory Address | DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians