Test Price
2,800 AED✅ Home Collection Available
IRAK4 Gene Invasive Pneumococcal Disease (Recurrent, Isolated Type 1) Genetic Test in UAE 2800 AED – 2026 DHA Guidelines
DHA-Certified Laboratoryتحليل جين IRAK4 لمرض المكورات الرئوية الغازية المتكرر المعزول من النوع الأول (تسلسل الحمض النووي NGS) في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
● Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
● Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy (8 AM – 11 PM).
● Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by a Senior Medical Geneticist.
● Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
تقرير سريري دقيق بنسبة 99.9% بفضل المعالجة المعتمدة ISO. خدمة سحب منزلي للمرضى تشمل النقل المبرد المعتمد. استشارة طبية هاتفية بعد الفحص لتفسير النتائج. التحقق من التأمين متاح عبر واتساب.
Overview
This advanced NGS panel sequences the entire coding region of the IRAK4 gene to detect pathogenic variants causative of autosomal recessive IRAK-4 deficiency, a primary immunodeficiency marked by recurrent life-threatening invasive pneumococcal disease. يكشف هذا الاختبار المتطور عن الطفرات في جين IRAK4 المسؤولة عن نقص المناعة الأولي الوراثي المترافق مع عدوى المكورات الرئوية الغازية المتكررة.
| Feature | Our IRAK4 NGS Test | Closest Alternative (Single-Gene Sanger) |
|---|---|---|
| Precision | 99.9% analytical sensitivity & specificity; full gene coverage | ~98% sensitivity; only known hotspots analyzed |
| Method | Next-Generation Sequencing (NGS) with MLPA backup | Bidirectional Sanger sequencing of selected exons |
| Turnaround | 3 to 4 Weeks (report includes expert clinical annotation) | 6–8 Weeks; limited interpretive support |
Physician Insight & Safety Protocol
“As a clinical immunologist, I recommend this test for patients presenting with recurrent, invasive streptococcal infections after 2 years of age with documented impaired response to pneumococcal vaccines. A positive result confirms IRAK-4 deficiency and guides prophylactic antibiotics and intravenous immunoglobulin therapy, while a negative report must still be interpreted in the context of the patient’s complete immunological workup. Please remember that genetic findings are one piece of the diagnostic puzzle.”
— Dr. PRABHAKAR REDDY, DHA License: 61713011
⚠️ Medication Warning
Do not discontinue prescribed medication, especially prophylactic antibiotics or immunoglobulin replacement, without consulting your doctor. This test is intended to confirm a genetic diagnosis, not to manage acute infection.
Exclusion Criteria & ER Red Flags
- Active high fever (>38.5°C) or signs of systemic infection; postpone home collection until clinically stable.
- For minors, written parental/guardian consent is mandatory per UAE CDS Law 2026.
- If the patient exhibits severe respiratory distress, cyanosis, hypotension, or altered consciousness, proceed immediately to the nearest emergency department—do not wait for test results.
Patient FAQ & Clinical Guidance
Q: What exactly does the IRAK4 gene test detect and why is it recommended in the UAE?
It identifies disease-causing mutations in the IRAK4 gene that lead to a primary immunodeficiency, predisposing individuals to recurrent invasive pneumococcal infections, a condition particularly relevant for families in the UAE with consanguineous backgrounds.
يكشف عن الطفرات المسببة للمرض في جين IRAK4 المسببة لنقص مناعي أولي، وهو اختبار مهم في الإمارات نظراً لارتفاع نسبة زواج الأقارب.
Q: How should I prepare for the blood draw and what are the sample requirements?
Provide your detailed clinical history and, if available, a genetic counselling pedigree chart for the family; we accept whole blood, extracted DNA, or a single drop of blood on an FTA card with full cold-chain transport.
قدم تاريخك السريري المفصل، ويفضل مخطط النسب الجيني للعائلة؛ تُقبل العينات على شكل دم كامل، DNA مستخلص، أو قطرة دم على بطاقة FTA مع النقل المبرد.
Q: When will I receive the results and what does a “positive” finding mean for my child?
Results are delivered in 3–4 weeks with a comprehensive clinical report; a positive result confirms IRAK-4 deficiency, prompting immediate specialist referral for prophylactic antibiotics and lifelong infection prevention strategies.
تصدر النتائج خلال ٣-٤ أسابيع مع تقرير سريري مفصل؛ النتيجة الإيجابية تؤكد نقص IRAK4 وتستدعي تحويلاً فورياً إلى اختصاصي المناعة للعلاج الوقائي.
UAE Regulatory Compliance & Data Privacy
This genetic test is performed under strict adherence to Federal Decree-Law No. 41 of 2024 (Art. 87) on medical laboratory licensing, UAE PDPL (Federal Decree-Law No. 45 of 2021), and CDS Law 2026 provisions for minors. All genomic data is processed within UAE borders through our ISO 9001:2015 certified facility (Cert: INT/EGQ/2509DA/3139, MOHAP License: 9834453).
For immediate booking or insurance verification, contact our medical concierge team:
WhatsApp: +971 54 548 8731 | Home Collection 8 AM – 11 PM, 7 days a week
IRAK4 Invasive Pneumococcal Disease Genetic – 2800 AED. TAT: 3–4 Weeks. Sample: Blood, DNA, or FTA card.
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التحقق من التغطية التأمينية
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
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All reports reviewed by DHA-Certified physicians