Test Price
2,800 AED✅ Home Collection Available
IL36RN Gene (Generalized Pustular Psoriasis) Genetic Test in Dubai & UAE | Price 2,800 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Processing
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM)
- Clinical Guidance: Complimentary Telephonic Post-Test Genetic Counseling by a Consultant Medical Geneticist
- Insurance: Direct Billing Verification Available via WhatsApp +971 54 548 8731
Test Overview & Methodology
The IL36RN Gene Genetic Test by DNA Labs UAE employs advanced Next-Generation Sequencing (NGS) to detect pathogenic variants in the IL36RN gene, the primary genetic driver of Generalized Pustular Psoriasis (GPP). This definitive molecular analysis enables accurate diagnosis, prognosis, and personalized therapeutic strategies for dermatologists, clinical geneticists, and immunologists managing hereditary autoinflammatory skin disorders.
| Feature | Our Test (NGS IL36RN) | Closest Alternative (Single-Gene Sanger) |
|---|---|---|
| Precision (Diagnostic Sensitivity) | 99.9% | ~85-90% |
| Methodology | Next-Generation Sequencing (Whole Gene) | Capillary Electrophoresis (Exon-by-Exon) |
| Turnaround Time (TAT) | 3 – 4 Weeks | 4 – 6 Weeks |
| Variant Detection | SNVs, indels, and CNVs (comprehensive) | Limited to pre-selected exons |
| Accreditation | ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) | Often not ISO-accredited |
Physician Insight & Safety Protocols
"Identifying a pathogenic variant in the IL36RN gene provides a definitive diagnosis for Generalized Pustular Psoriasis, distinguishing it from other pustular dermatoses. This allows for targeted biologic therapy and informed family counseling regarding the autosomal recessive inheritance pattern. It is crucial to correlate genetic findings with the complete clinical picture. Never alter or discontinue prescribed immunosuppressive or biologic therapy without consulting your managing dermatologist or geneticist. Our multidisciplinary team at DNA Labs UAE is committed to guiding you through the clinical implications of your genetic results."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication & Clinical Advisory
Do not discontinue any prescribed biologic, corticosteroid, or immunosuppressant medication without explicit advice from your treating physician. Genetic testing is an adjunct to, not a replacement for, standard clinical monitoring.
Exclusion & Emergency Red Flags
- Exclusion: Active severe systemic infection requiring acute intervention, recent major surgery within the past 30 days, or inability to provide informed consent for genetic testing as per Federal Decree-Law No. 4 of 2016.
- Emergency: Sudden widespread pustular eruption accompanied by high fever, chills, severe malaise, or joint pain may indicate an acute GPP flare (von Zumbusch pattern). Seek immediate emergency medical care.
Patient FAQ & Clinical Guidance
1. What is the IL36RN gene and how does it relate to my psoriasis?
The IL36RN gene provides instructions for making the interleukin-36 receptor antagonist (IL-36Ra). A deficiency in IL-36Ra due to gene mutations leads to unchecked inflammation in the skin, specifically triggering Generalized Pustular Psoriasis (GPP). This test determines if a pathogenic variant in this gene is the underlying cause of your condition.
2. How long does it take to receive my genetic test results?
From the moment your blood sample is received by our laboratory in Dubai Healthcare City, results are typically available within 3 to 4 weeks. This turnaround time ensures comprehensive whole-gene sequencing, rigorous bioinformatic analysis, and expert clinical interpretation by our Consultant Medical Geneticist.
3. Will my health insurance cover the cost of this IL36RN genetic test?
Many UAE health insurers recognize the medical necessity of IL36RN gene sequencing for diagnosing GPP and may provide coverage. DNA Labs UAE offers a complimentary direct billing verification service. Simply send a picture of your insurance card via WhatsApp to +971 54 548 8731, and our team will confirm your coverage eligibility.
UAE Regulatory & Data Privacy Adherence
Federal Data Privacy & Clinical Governance Compliance
Your genetic data is highly sensitive and protected under stringent UAE federal laws. DNA Labs UAE strictly adheres to the following regulatory frameworks:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL): Governing the processing, storage, and transfer of your personal health data.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields: Regulating the security and confidentiality of electronic health records and telehealth communications.
- Federal Decree-Law No. 4 of 2016 on Medical Liability: Governing clinical genetic testing standards, patient consent protocols, and physician accountability.
Your results are securely encrypted and will only be shared with the referring physician or directly with you upon explicit, informed consent.
Clinical & Logistical Metadata
| Test Name | IL36RN Gene (Generalized Pustular Psoriasis) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 – 4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection Available) |
| Methodology Used | Next-Generation Sequencing (NGS) – Whole Gene Analysis |
| ICD-10-CM Code | L40.1 – Generalized pustular psoriasis |
| LOINC Code | 94763-4 – IL36RN gene mutation analysis |
| DHA Facility License & Laboratory Address |
License No.: 1143 Address: Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE Corporate Lab: DNA Labs UAE |
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ISMS 27001:2022
ISO Accredited
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All reports reviewed by DHA-Certified physicians