Test Price
2,800 AED✅ Home Collection Available
IKBKG Gene (NEMO) Immunodeficiency Genetic Test in UAE | 2800 AED | DHA-Licensed
Executive Summary & Core Metrics
- Accuracy & Sensitivity: 99.9% diagnostic sensitivity via ISO 9001:2015 certified processing (Cert: INT/EGQ/2509DA/3139).
- Premium Home Collection: VIP Mobile Phlebotomy – temperature-controlled cold-chain collection at your door, daily 8 AM to 11 PM.
- Post‑Test Clinical Guidance: Complimentary telephonic expert interpretation with DHA‑licensed clinicians.
- Insurance & Billing: Direct billing verification – send your policy details via WhatsApp to +971 54 548 8731.
- Regulatory Adherence: Fully compliant with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL), Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, and Federal Decree‑Law No. 4 of 2016 on Medical Liability.
Test Overview & Methodology
The IKBKG gene (NEMO) genetic test detects pathogenic variants linked to Incontinentia Pigmenti, Hypohidrotic Ectodermal Dysplasia with Immunodeficiency, and isolated immunodeficiency. Leveraging Next Generation Sequencing (NGS) with full exon coverage and splice‑site analysis, it delivers a definitive molecular diagnosis to guide dermatological, immunological, and family planning management.
| Feature | Our NGS Test | Single‑Gene Sanger Sequencing |
|---|---|---|
| Methodology | NGS – Massive Parallel Sequencing (Full Gene & Splice Sites) | Capillary Electrophoresis – Targeted Amplicons |
| Turnaround Time | 3 – 4 Weeks | 4 – 6 Weeks |
| Variant Detection | >99.9% sensitivity for SNVs/Indels; also detects large deletions/duplications (CNV)* | Limited to point mutations in covered exons; CNV detection unreliable |
| Clinical Utility | Complete IKBKG molecular profiling for diagnosis, carrier screening & prognosis | Partial screening; often requires reflex to NGS if negative |
*Validated by orthogonal methods per DHA/MOHAP NGS guidelines.
Physician Insight & Safety Protocols
“As a clinical geneticist, I recognize that receiving a genetic test result for IKBKG variants can be life‑changing, particularly for families. It is essential to interpret findings within the full context of clinical presentation and family history. This test provides a molecular roadmap that empowers personalized care, early surveillance, and informed reproductive choices.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA ID: 9294403
Medication Advisory
⚠️ Do not discontinue prescribed medication without consulting your doctor.
Patient Safety: Exclusion Criteria & Urgent Red Flags
- Exclusion: Known coagulopathy (severe hemophilia), platelet disorders, or current anticoagulant therapy that cannot be safely interrupted – consult our DHA nurse for alternative dried‑blood spot collection.
- Exclusion: Active severe infection with haemodynamic instability; collection must be postponed until clinically stable.
- ER Red Flag: Sudden onset of respiratory distress, high fever with septic appearance, or uncontrolled bleeding at the phlebotomy site → seek emergency medical attention immediately.
- ER Red Flag: Signs of anaphylaxis within minutes of sample collection – call 998 (UAE ambulance) and head to the nearest hospital ER.
Patient FAQ & Clinical Guidance
1. What is the IKBKG gene and how does this test help?
This NGS test analyzes the IKBKG gene to diagnose Incontinentia Pigmenti and related immunodeficiencies with 99.9% accuracy. The IKBKG gene (NEMO) is essential for NF‑κB signaling, and pathogenic variants cause a spectrum of disorders including skin, immune, and dental abnormalities. Our test examines all coding exons and splice junctions, providing a definitive molecular answer that enables accurate prognosis, tailored surveillance, and informed family planning.
2. What sample do I need and how is the home collection performed?
A simple blood draw or DNA from an FTA card is collected via our DHA-licensed home phlebotomy service. We accept whole blood (EDTA tube), extracted DNA, or a single drop of blood on an FTA card for maximum convenience. Our licensed phlebotomist arrives with ISO‑certified cold‑chain packaging, ensuring sample integrity from your home to our CAP‑accredited laboratory.
3. How long do results take and what does the report contain?
Results are ready in 3‑4 weeks and include a comprehensive pathogenicity interpretation of any detected variants. Your report classifies variants as pathogenic, likely pathogenic, or of uncertain significance, aligned with ACMG guidelines. It also includes inheritance pattern, clinical correlation suggestions, and a dedicated section for your referring physician. A post‑genetic counseling call is included to explain findings and next steps.
UAE Regulatory & Data Privacy Adherence
Comprehensive Legal Compliance
This genetic testing service operates fully under the following UAE legal frameworks:
- Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) – ensuring strict patient data privacy and security.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – governing electronic health data handling.
- Federal Decree‑Law No. 4 of 2016 on Medical Liability – safeguarding patient consent and clinical safety.
Our laboratory is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139) and operates under DHA Facility License No. 1143. All genetic counseling and result disclosures are performed by DHA-licensed professionals.
Clinical & Logistical Metadata
| Test Name | IKBKG Gene (NEMO) Immunodeficiency Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 – 4 weeks |
| Sample Type / Matrix | Whole blood (EDTA), extracted DNA, or FTA card blood spot |
| Methodology Used | Next Generation Sequencing (NGS) – full gene and splice site analysis |
| ICD-10-CM Code | Q82.3 (Incontinentia Pigmenti), D82.8 (Hypohidrotic Ectodermal Dysplasia with Immunodeficiency) |
| LOINC Code | 81247-9 (IKBKG gene mutations identified in Blood by Sequencing) |
| DHA Facility License & Laboratory Address | License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians