Test Price
2,800 AED✅ Home Collection Available
IKBKG Gene (NEMO) Immunodeficiency Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين IKBKG (العوز المناعي) في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary & UAE Trust Guarantee
- Accuracy & Sensitivity: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Home Collection: Paid Hospital‑Grade VIP Mobile Phlebotomy – ISO Certified Cold‑Chain collection at your door, 8 AM‑11 PM daily.
- Post‑Test Clinical Guidance: Complimentary telephonic expert interpretation with DHA‑licensed clinicians.
- Insurance & Billing: Direct Billing Verification – send your policy details via WhatsApp to +971 54 548 8731.
- Regulatory Adherence: Fully compliant with Federal Decree‑Law No. 41 of 2024 (Art. 87), CDS Law 2026 (Minors), and UAE PDPL Data Privacy.
ملخص تنفيذي: دقة تشخيصية 99.9% عبر معامل معتمدة وفق الآيزو 9001:2015، خدمة سحب منزلي متميزة بنظام السلسلة الباردة، استشارة هاتفية بعد النتيجة، وإمكانية التحقق المباشر من التغطية التأمينية عبر واتساب 971545488731+.
Clinical Overview & Diagnostic Precision
The IKBKG gene (NEMO) Genetic Test detects pathogenic variants linked to Incontinentia Pigmenti, Hypohidrotic Ectodermal Dysplasia with Immunodeficiency, and isolated immunodeficiency. Leveraging Next Generation Sequencing with full exon coverage and splice‑site analysis, it delivers a definitive molecular diagnosis to guide dermatological, immunological, and family planning management.
| Feature | Our NGS Test | Single‑Gene Sanger Sequencing |
|---|---|---|
| Methodology | NGS – Massive Parallel Sequencing (Full Gene & Splice Sites) | Capillary Electrophoresis – Targeted Amplicons |
| Turnaround Time | 3 – 4 Weeks | 4 – 6 Weeks |
| Variant Detection | >99.9% sensitivity for SNVs/Indels; also detects large deletions/duplications (CNV)* | Limited to point mutations in covered exons; CNV detection unreliable |
| Clinical Utility | Complete IKBKG molecular profiling for diagnosis, carrier screening & prognosis | Partial screening; often requires reflex to NGS if negative |
*Validated by orthogonal methods per DHA/MOHAP NGS guidelines.
Physician Insight & Safety Protocol
“As a clinician, I understand that genetic testing for IKBKG variants can feel overwhelming, especially when it concerns your child’s health or your own. It is crucial to interpret results in the context of your complete clinical picture and family history, which we are here to support you with. Please remember that a genetic diagnosis is not a sentence, but a roadmap to personalized care and preventive strategies.”
— Dr. PRABHAKAR REDDY, DHA License: 61713011
⚠️ Do not discontinue prescribed medication without consulting your doctor.
Patient Safety: Exclusion Criteria & Urgent Red Flags
- Exclusion: Known coagulopathy (severe hemophilia), platelet disorders, or current anticoagulant therapy that cannot be safely interrupted – consult our DHA nurse for alternative dried‑blood spot collection.
- Exclusion: Active severe infection with haemodynamic instability; collection must be postponed until clinically stable.
- ER Red Flag: Sudden onset of respiratory distress, high fever with septic appearance, or uncontrolled bleeding at the phlebotomy site → seek emergency medical attention immediately.
- ER Red Flag: Signs of anaphylaxis within minutes of sample collection – call 998 (UAE ambulance) and head to the nearest hospital ER.
Patient FAQ & Clinical Guidance
Q1: What is the IKBKG gene and how does this test help?
This NGS test analyzes the IKBKG gene to diagnose Incontinentia Pigmenti and related immunodeficiencies with 99.9% accuracy. The IKBKG gene (NEMO) is essential for NF‑κB signaling, and pathogenic variants cause a spectrum of disorders including skin, immune, and dental abnormalities. Our test examines all coding exons and splice junctions, providing a definitive molecular answer that enables accurate prognosis, tailored surveillance, and informed family planning.
Q2: What sample do I need and how is the home collection performed?
A simple blood draw or DNA from an FTA card is collected via our DHA-licensed home phlebotomy service. We accept whole blood (EDTA tube), extracted DNA, or a single drop of blood on an FTA card for maximum convenience. Our licensed phlebotomist arrives with ISO‑certified cold‑chain packaging, ensuring sample integrity from your home to our CAP‑accredited laboratory.
Q3: How long do results take and what does the report contain?
Results are ready in 3‑4 weeks and include a comprehensive pathogenicity interpretation of any detected variants. Your report classifies variants as pathogenic, likely pathogenic, or of uncertain significance, aligned with ACMG 2026 guidelines. It also includes inheritance pattern, clinical correlation suggestions, and a dedicated section for your referring physician. A post‑ genetic counseling call is included to explain findings and next steps.
الأسئلة الشائعة بالعربية
س1: ما هو جين IKBKG وكيف يساعد هذا الاختبار؟
يقوم اختبار NGS هذا بتحليل جين IKBKG لتشخيص سلس البول الصباغي ونقص المناعة المرتبط بدقة 99.9%. جين IKBKG (NEMO) ضروري لإشارات NF‑κB، وتسبب طفراته اضطرابات جلدية ومناعية وأسنانية. يفحص اختبارنا جميع الإكسونات ومواقع الوصل، موفراً تشخيصاً جزيئياً قطعياً يساعد في التكهن الطبي والمراقبة والتخطيط الأسري.
س2: ما العينة المطلوبة وكيف يتم السحب المنزلي؟
يتم سحب عينة دم بسيط أو حمض نووي من بطاقة FTA عبر خدمة السحب المنزلي المرخصة من هيئة الصحة بدبي. نقبل الدم الكامل أو الحمض النووي المستخلص أو قطرة دم على بطاقة FTA. يأتي الفني المعتمد بسيارة مزودة بنظام السلسلة الباردة للتبريد، محافظاً على سلامة العينة حتى وصولها إلى مختبرنا المعتمد.
س3: كم تستغرق النتائج وماذا يتضمن التقرير؟
تكون النتائج جاهزة خلال 3‑4 أسابيع وتشمل تفسيراً شاملاً لمدى إمراضية أي طفرة مكتشفة. يصنف التقرير الطفرات كمُمْرِضة أو محتملة الضرر أو غير محددة الأهمية، متوافقاً مع إرشادات ACMG 2026. يتضمن أيضاً نمط الوراثة واقتراحات طبية وقسماً للطبيب المعالج، إضافة إلى استشارة وراثية هاتفية مجانية لشرح النتائج والخطوات التالية.
Regulatory Framework: This service is governed by UAE Federal Decree‑Law No. 41 of 2024 on Personal Data Protection, CDS Law 2026 (Minors’ Genetic Testing Consent), and DHA/MOHAP Molecular Pathology Standards.
Lab Accreditation: ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139); DHA Facility License: 9834453.
Genetics Specialists Involved: Dermatologist (Incontinentia Pigmenti), Clinical Immunologist, Medical Geneticist.
Direct Contact & Home Collection Booking: WhatsApp +971 54 548 8731
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians