Test Price
2,800 AED✅ Home Collection Available
IGHMBP2 Gene Distal Hereditary Motor Neuropathy Type 6 (dHMN6/SMARD1) Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين IGHMBP2 لمرض الاعتلال العصبي الحركي الوراثي البعيد من النوع السادس في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary & UAE Compliance
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified NGS & confirmatory testing.
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by DHA-licensed clinical geneticists.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
الفحص الجيني لجين IGHMBP2 لتشخيص اعتلال الأعصاب الحركية الوراثي البعيد من النوع السادس (SMARD1 / dHMN6) في مختبر معتمد من هيئة الصحة بدبي وطبقاً للمرسوم بقانون اتحادي رقم 41 لسنة 2024 بشأن تنظيم البيانات الجينية. دقة تشخيصية تصل إلى 99.9% مع استشارة وراثية قبل وبعد الفحص، وخدمة سحب منزلي على مستوى الإمارات.
Test Overview
This comprehensive next-generation sequencing (NGS) test analyzes the entire coding region and flanking intronic boundaries of the IGHMBP2 gene, associated with autosomal recessive distal hereditary motor neuropathy type 6 (dHMN6) and severe spinal muscular atrophy with respiratory distress type 1 (SMARD1). It is indicated for individuals with clinical features of distal motor weakness, suspected hereditary neuropathy, or a family history of IGHMBP2-related disorders.
| Feature | Our Test (DNA Labs UAE) | Closest Alternative (Conventional Sanger) |
|---|---|---|
| Precision | High-coverage NGS (>100x) with CNV detection, Sanger confirmation of all pathogenic/likely pathogenic variants | Targeted Sanger sequencing of selected exons, may miss deep intronic or copy number changes |
| Method | NGS (Agilent SureSelect/MGI platform) + MLPA/Array CGH if indicated | Sanger sequencing only |
| Speed | 3–4 Weeks | 4–6 Weeks (limited throughput) |
Physician Insight & Safety Protocol
Clinical Note from Dr. PRABHAKAR REDDY (DHA License: 61713011): “The IGHMBP2 NGS test provides critical molecular confirmation for hereditary motor neuropathy, enabling precise prognostication and genetic counseling. However, a negative result does not exclude other forms of inherited neuropathy, and I emphasize that clinical correlation with EMG/NCS and neurological evaluation remains essential.”
⚠️ Medication Warning:
Do not discontinue prescribed medication without consulting your doctor. This test does not replace ongoing neurological management.
Exclusion Criteria & ER Red Flags
- Acute respiratory distress or rapidly progressive weakness requiring urgent medical attention – proceed immediately to the nearest emergency department.
- Inability to provide a blood sample due to severe coagulopathy or active infection.
- Prior allogeneic bone marrow transplant may interfere with germline genetic testing.
- This test is not suitable for somatic mutation detection or pharmacogenomics.
Frequently Asked Questions
1. What does the IGHMBP2 gene test detect and how long do results take?
Snippet: This NGS detects single nucleotide variants, small indels, and copy number changes across the entire IGHMBP2 gene to confirm distal hereditary motor neuropathy type 6 or SMARD1.
The analysis covers all coding exons and splice sites. Results are typically available within 3 to 4 weeks from sample receipt due to comprehensive quality control and confirmatory Sanger sequencing.
يرصد هذا الفحص الطفرات النقطية والحذف/الإدراج الصغيرة والتغيرات في عدد النسخ للجين IGHMBP2 لتأكيد الاعتلال العصبي الحركي الوراثي البعيد النوع 6 أو ضمور العضلات الشوكي مع الضائقة التنفسية النوع 1. تصدر النتائج بعد 3 إلى 4 أسابيع مع تأكيد سانجر.
2. Is home sample collection available across the UAE?
Snippet: Yes, our ISO-certified phlebotomy team offers hospital-grade home collection throughout Dubai, Abu Dhabi, Sharjah, and all emirates from 8 AM to 11 PM.
A trained phlebotomist arrives with a temperature-controlled transport kit to ensure sample stability. You can schedule via WhatsApp at +971 54 548 8731 and provide insurance details for direct billing.
نعم، نوفر خدمة سحب الدم المنزلي على مستوى دولة الإمارات من الساعة 8 صباحاً حتى 11 مساءً عبر فريق معتمد وباستخدام حاويات نقل مبرّدة، مع إمكانية التواصل عبر واتساب على الرقم +971 54 548 8731.
3. How is my genetic data protected under UAE law?
Snippet: All genomic data is stored and processed in compliance with UAE Federal Decree-Law No. 41 of 2024, the Personal Data Protection Law, and our ISO 9001:2015 certified quality management system.
Your sample and results are de-identified, encrypted, and not shared with third parties without explicit consent. A genetic counseling session is required before testing to ensure informed consent.
نلتزم بتخزين البيانات الجينية ومعالجتها وفقاً للمرسوم بقانون اتحادي رقم 41 لسنة 2024 وقانون حماية البيانات الشخصية الإماراتي، مع جلسة استشارة وراثية إلزامية قبل الفحص لضمان الموافقة المستنيرة.
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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All reports reviewed by DHA-Certified physicians