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Test Price

700 AED

✅ Home Collection Available

IgH Gene Rearrangement by FISH for Multiple Myeloma (MM) in UAE | 700 AED | DNA Labs UAE

Executive Summary & Core Metrics

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity achieved through ISO 9001:2015 accredited processing and stringent quality controls.
  • Logistics: Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
  • Clinical Guidance: Complimentary telephonic post‑test result interpretation by DHA‑licensed clinicians.
  • Insurance: Direct billing eligibility check via WhatsApp: +971 54 548 8731.

Test Overview & Methodology

This fluorescence in‑situ hybridization (FISH) assay examines the immunoglobulin heavy chain (IgH) gene locus for chromosomal rearrangements commonly present in multiple myeloma (MM) and related plasma cell neoplasms. It provides critical molecular information to support early diagnosis, risk stratification, and minimal residual disease monitoring.

Feature Our IgH FISH Test Closest Alternative (PCR Clonality Assay)
Methodology Fluorescence In‑Situ Hybridization (FISH) PCR‑based BIOMED‑2 clonality assay
Diagnostic Sensitivity >95% for clonal IgH rearrangements ~80–90%
Turnaround Time 3–4 working days 7–10 working days
Sample Requirement Bone marrow aspirate or peripheral blood Bone marrow aspirate
Detection of Cryptic Translocations Excellent (e.g., t(4;14), t(14;16)) Limited

Physician Insight & Safety Protocols

Mr. Prabhakar Reddy Kalathoor (Specialist Diagnostic Radiology, DHA Registration ID: 61713011) emphasizes: “A positive IgH FISH result supports the diagnosis of multiple myeloma but must be correlated with serum protein electrophoresis, immunofixation, and bone marrow biopsy findings. Clinical correlation is essential to avoid overdiagnosis. Consult your hematologist for a personalized treatment plan.”

Medication Warning

Do not discontinue prescribed medication — including corticosteroids, immunomodulatory drugs, or any maintenance therapy — without consulting your treating physician.

Exclusion Criteria & ER Red Flags

  • Exclusion Criteria: Active bleeding disorder (e.g., hemophilia, severe thrombocytopenia), ongoing infection at the venipuncture site, inability to provide informed consent.
  • Red Flags – Seek emergency care if you experience: prolonged bleeding from the puncture site, fever >38°C, increasing pain or swelling, or signs of systemic infection within 24 hours of collection.

Patient FAQ & Clinical Guidance

1. What is an IgH gene rearrangement FISH test?

The IgH FISH detects abnormal immunoglobulin heavy chain gene rearrangements to diagnose multiple myeloma and related plasma cell disorders.

2. Why might I need a bone marrow sample instead of only blood?

Bone marrow aspiration provides a higher concentration of plasma cells, increasing detection sensitivity compared to peripheral blood alone.

3. How long do results take and how will I receive them?

Final results are typically available within 3–4 working days and are delivered via secure electronic report to your ordering physician.

UAE Regulatory & Data Privacy Adherence

DNA Labs UAE operates in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Our DHA facility license number is 1143. All clinical procedures adhere to ethical standards outlined in Federal Decree-Law No. 4 of 2016 on Medical Liability. Laboratory address: Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.

Clinical & Logistical Metadata

Test Name IgH Gene Rearrangement by FISH for Multiple Myeloma (MM)
Price (AED) 700 AED
Turnaround Time 3–4 working days
Sample Type / Matrix Bone Marrow Aspirate (Hospital Extraction Only)
Methodology Used Fluorescence In-Situ Hybridization (FISH)
ICD-10-CM Code C90.0
LOINC Code 49901-1
DHA Facility License & Laboratory Address DHA License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE

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