Test Price
2,800 AEDโ Home Collection Available
IFNGR2 Gene Analysis for Atypical Mycobacterial Susceptibility | Genetic Test in Dubai
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance by DHA-licensed genetics specialists for result interpretation.
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
This next-generation sequencing test screens the entire IFNGR2 gene for pathogenic variants linked to Mendelian susceptibility to mycobacterial disease (MSMD), empowering precise diagnosis, targeted prevention, and family risk assessment. The assay achieves greater than 99.9% sensitivity through full exon coverage including splice-site regions, with all positive findings confirmed by orthogonal Sanger sequencing to eliminate false positives.
| Feature | Our Test (NGS) | Closest Alternative (Single-Gene Sanger) |
|---|---|---|
| Precision | >99.9% sensitivity, full exon coverage & splice sites | Limited to known hotspot regions, may miss deep intronic variants |
| Method | Next-Generation Sequencing (Illumina) with Sanger confirmation | Capillary electrophoresis of selected exons |
| Turnaround | 3 โ 4 Weeks | 6 โ 8 Weeks (multi-step amplification) |
| Accreditation | ISO 9001:2015 (DHA/MOHAP Compliant) | Often non-accredited or local only |
Physician Insight & Safety Protocols
โAs a DHA-licensed Consultant Medical Geneticist, I emphasize that comprehensive sequencing of IFNGR2 provides definitive molecular evidence for Mendelian susceptibility to mycobacterial disease. However, genetic findings must always be interpreted alongside immunological phenotyping, family history, and clinical presentation to guide decisions regarding antimicrobial prophylaxis or immunomodulatory therapy. A single genetic variant should never be used in isolation to dictate treatment.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
โ Medication Advisory
Do not discontinue prescribed antibiotics, antimicrobials, or immunomodulatory therapy without consulting your treating physician. Genetic test results may inform long-term management but should never prompt unsupervised changes to your current medication regimen.
Patient Safety & Exclusion Criteria
- Mandatory Pre-test Genetic Counseling: A documented counseling session and three-generation pedigree chart are required prior to testing in accordance with UAE Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Minor Consent: For individuals under 18 years, written consent from a legal guardian is mandatory as per UAE Child Rights Law (Wadeemaโs Law).
- Sample Integrity: Whole blood (EDTA), extracted DNA (minimum 1 ยตg), or one dried blood spot on an FTA card are accepted. Hemolyzed, lipemic, or clotted samples will be rejected.
- ER Red Flags: If you develop rapidly spreading skin lesions, high fever unresponsive to antipyretics, or breathing difficulties while awaiting results, seek emergency medical care immediately.
Patient FAQ & Clinical Guidance
1. What does the IFNGR2 gene test detect?
This test identifies pathogenic DNA variants in the IFNGR2 gene that cause extreme susceptibility to atypical mycobacterial infections. The result enables precise molecular diagnosis, guides targeted antimicrobial prophylaxis, and informs family cascade screening for at-risk relatives.
2. How is the sample collected and is home service available?
A routine blood draw, a purified DNA sample, or a single drop on an FTA card is required. We offer VIP home collection by DHA-licensed phlebotomists using ISO-certified cold-chain transport daily from 8 AM to 11 PM across Dubai and the Northern Emirates.
3. Is this test covered by health insurance in the UAE?
We facilitate direct billing with major UAE insurers including Daman, AXA, Bupa, and others. Verify your coverage instantly via WhatsApp at +971 54 548 8731 and our dedicated team will handle pre-approval within hours.
UAE Regulatory & Data Privacy Adherence
Data Protection & Health Information Governance
Your genetic data is processed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genomic information is encrypted, access-controlled, and retained only for the duration necessary for clinical reporting. We do not share your genetic data with third parties without explicit written consent as mandated by UAE health data governance frameworks.
Our laboratory operates under DHA Facility License Number 1143 and adheres to ISO 9001:2015 quality management standards, ensuring that every step from sample accession to result delivery meets stringent regulatory oversight.
Clinical & Logistical Metadata
| Test Name | IFNGR2 Gene Analysis (Atypical Mycobacterial Susceptibility) โ Next-Generation Sequencing |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 โ 4 Weeks |
| Sample Type / Matrix | Whole blood (EDTA), extracted genomic DNA, or dried blood spot (FTA card) |
| Methodology Used | Next-Generation Sequencing (Illumina) with orthogonal Sanger confirmation |
| ICD-10-CM Code | D84.8 |
| LOINC Code | 81247-9 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE โ DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians