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Test Price

2,800 AED

✅ Home Collection Available

IARS2 Gene Genetic Test for Syndromic Disorders | UAE | 2,800 AED | DHA Licensed

Executive Summary & Core Metrics

Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 accredited NGS processing. Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection – available daily from 8 AM to 11 PM. Clinical Guidance: Complimentary post-test telephonic result interpretation with a genetic counsellor. Insurance: Direct billing verification via WhatsApp at +971 54 548 8731.

Test Overview & Methodology

The IARS2 Genetic Test uses deep next-generation sequencing (NGS) to examine every coding region of the IARS2 gene, confirming autosomal recessive syndromic disease presenting with congenital cataracts, growth hormone deficiency, sensory neuropathy, sensorineural hearing loss, and skeletal dysplasia. Our Dubai laboratory merges ISO 9001:2015‑accredited wet‑lab and bioinformatics pipelines with DHA‑licensed cold‑chain home collection, delivering clinically actionable results in 3–4 weeks.

Feature Our IARS2 NGS Test Standard Hospital NGS Panel
Precision 99.9% analytical sensitivity (deep single‑gene coverage) ~97% for IARS2; risk of missed low‑frequency variants
Methodology Full‑length NGS with copy‑number variant analysis Multigene panel; exon‑level coverage may vary
Turnaround 3–4 Weeks (ISO cold‑chain home collection) 4–6 Weeks; hospital queue delays

Physician Insight & Safety Protocols

“This test empowers your family with a clear diagnosis, guides targeted surveillance for eye, endocrine, and neurological complications, and enables informed family planning. Ensure you undergo pre‑ and post‑test genetic counselling. Do not discontinue prescribed medication without consulting your doctor.

— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Pre‑Test Advisory

  • Ensure a valid referral from a specialist (endocrinologist, ophthalmologist, neurologist, or clinical geneticist)
  • Avoid blood sample collection during an acute febrile illness (body temperature ≥38.5°C)
  • Inform the phlebotomist of any anticoagulant therapy or bleeding disorder
  • Informed consent must be signed; for minors, parental consent is required per Federal Decree‑Law No. 4 of 2016 on Medical Liability

Safety Exclusion Criteria

  • Acute febrile illness (body temperature ≥38.5°C) on the day of sample collection
  • Severe coagulopathy (INR >2.5, platelets <50,000/µL) or current anticoagulant therapy bridging
  • Active skin infection at the venipuncture site
  • Inability to provide legally valid informed consent (must be resolved for minors per Federal Decree‑Law No. 4 of 2016 on Medical Liability)

ER Red Flags – Seek Immediate Emergency Care

  • Sudden, painless vision loss or severe ocular pain
  • New‑onset focal neurological deficits (facial asymmetry, limb weakness, slurred speech)
  • Rapidly worsening hearing loss with vertigo

Patient FAQ & Clinical Guidance

1. What does the IARS2 NGS test detect, and who should consider it?

The IARS2 NGS test detects mutations causing cataracts, growth deficiency, neuropathy, hearing loss, and skeletal dysplasia. This single‑gene sequencing test identifies even rare pathogenic variants in patients with clinical symptoms matching the IARS2‑related syndromic spectrum. All paediatric patients require parental consent per Federal Decree‑Law No. 4 of 2016 on Medical Liability.

2. How is the sample collected and when will I get my results?

Sample is taken via DHA‑licensed VIP Mobile Phlebotomy from 8 AM to 11 PM using an ISO‑certified cold‑chain kit. DNA is extracted from the blood sample, and results are ready in 3–4 weeks. A pre‑test genetic counselling session is mandatory to draw a pedigree chart and confirm family history.

3. Is the IARS2 test covered by insurance in the UAE, and how do I verify?

Most UAE insurers cover medically indicated genetic tests. Send your policy copy via WhatsApp at +971 54 548 8731 for direct billing verification. Our team checks coverage against DHA and PDPL‑compliant data protection standards. The price is 2,800 AED with a 3–4‑week reporting time.

UAE Regulatory & Data Privacy Adherence

All patient data is handled in strict compliance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. The laboratory is DHA‑licensed (No. 1143) and operates under ISO 9001:2015 quality management (Cert. INT/EGQ/2509DA/3139). Clinical reporting follows the standards set by the Dubai Health Authority.

Clinical & Logistical Metadata

Test Name IARS2 Gene Genetic Test for Syndromic Disorders
Price (AED) 2,800 AED
Turnaround Time 3–4 Weeks (after sample receipt)
Sample Type / Matrix Peripheral Whole Blood – VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection
Methodology Used Next‑Generation Sequencing (NGS) with Copy‑Number Variant Analysis
ICD‑10‑CM Code Q87.8 (Other specified congenital malformation syndromes)
LOINC Code 91253-3 (IARS2 gene mutation analysis)
DHA Facility License & Address DHA License No. 1143 | DNA Labs UAE, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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All reports reviewed by DHA-Certified physicians