Test Price
2,800 AED✅ Home Collection Available
HTRA1 Gene (CARASIL) Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين HTRA1 (متلازمة كاراسيل) بتقنية التسلسل الجيني المتقدم في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary / الملخص التنفيذي
- ✓ 99.9% Diagnostic Sensitivity – ISO‑accredited processing ensures clinical‑grade precision for HTRA1 mutation detection.
- ✓ Premium Logistics: Hospital‑grade home collection (8 AM – 11 PM) with ISO‑certified cold‑chain transport.
- ✓ Clinical Guidance: Telephonic post‑test consultation by DHA‑licensed specialists to interpret results.
- ✓ Insurance: Direct billing verification via WhatsApp at +971 54 548 8731.
- ✓ Turnaround: 3–4 weeks for comprehensive NGS analysis.
حساسية تشخيصية بنسبة 99.9%، خدمة سحب منزلي فاخرة معتمدة، واستشارة طبية هاتفية بعد الفحص — كل ذلك وفق إرشادات هيئة الصحة بدبي لعام 2026.
Overview
This Next‑Generation Sequencing (NGS) test screens the HTRA1 gene for mutations causing CARASIL (cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy), an inherited small‑vessel disease. By analyzing all coding exons, it identifies pathogenic variants linked to early‑onset stroke, cognitive decline, and vascular dementia, empowering families and physicians in the UAE with actionable genetic data.
| Feature | Our Test (UAE Gold Standard) | Closest Alternative |
|---|---|---|
| Precision | Full‑gene NGS with 1000x depth, >99.9% sensitivity | Targeted Sanger sequencing of selected exons only |
| Method | Illumina‑based NGS, ISO 9001:2015 lab | Single‑gene Sanger; lower resolution |
| Speed & Support | 3–4 weeks with DHA‑licensed genetic counselling | 4–6 weeks; counselling may not be integrated |
Physician Insight & Safety Protocol
"A positive HTRA1 mutation confirms the diagnosis of CARASIL, especially in young adults with recurrent lacunar strokes or diffuse white matter changes. However, a negative result does not exclude all small‑vessel diseases, so clinical correlation with MRI, family history, and neurological exam remains paramount."
— Dr. PRABHAKAR REDDY, DHA License 61713011
Medication Warning
Do not discontinue or adjust prescribed medications (e.g., antiplatelets, statins) without consulting your treating physician. Genetic results do not replace ongoing clinical management.
Emergency Red Flags
- Sudden onset of severe headache, confusion, or vision loss
- Acute weakness or numbness on one side of the body (possible stroke)
- Loss of balance, difficulty speaking, or abrupt personality change
If any sign appears, proceed immediately to the nearest emergency department.
Exclusion Criteria
Test not recommended for individuals under 18 without court‑approved consent (CDS Law 2026); for women who are pregnant but seeking non‑urgent genetic screening, defer until after delivery. Recent blood transfusion (<2 weeks) may cause sample inadequacy.
Patient FAQ & Clinical Guidance
1. What does a positive HTRA1 test mean for my family?
A positive result confirms a genetic mutation causing CARASIL, which is inherited in an autosomal recessive manner — both parents must be carriers. تؤكد النتيجة الإيجابية وجود طفرة جينية تسبب متلازمة كاراسيل، وتنتقل بوراثة متنحية، مما يستدعي استشارة عائلية.
2. How should I prepare for the sample collection?
No fasting is required; our phlebotomist will collect a small blood sample (or a dried blood spot on an FTA card) at your home or office. لا حاجة للصيام، سيقوم فني المختبر بسحب عينة دم بسيطة (أو بقعة دم على بطاقة FTA) في منزلك أو مكان عملك.
3. Is this test covered by UAE health insurance?
Coverage varies; we provide direct billing verification with major UAE insurers — contact our team via WhatsApp for a fast eligibility check. تختلف التغطية حسب شركة التأمين؛ نوفر خدمة التحقق المباشر مع كبرى شركات التأمين في الإمارات عبر واتساب.
Regulatory Compliance: This adheres to UAE Federal Decree‑Law No. 41 of 2024 (Art. 87), UAE PDPL for genetic data privacy, and CDS Law 2026 for minors. Our facility holds ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) and DHA Facility License 9834453.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians