Test Price
2,800 AED✅ Home Collection Available
HRAS Gene Costello Syndrome Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين HRAS لمتلازمة كوستيلو بتقنية التسلسل الجيني من الجيل التالي في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary
- دقة تشخيصية فائقة: 99.9% Diagnostic Sensitivity achieved through ISO 9001:2015 accredited NGS processing and rigorous bioinformatics pipeline.
- خدمة سحب منزلي متميزة: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain transport & VIP Mobile Phlebotomy across all Emirates.
- استشارة طبية هاتفية: Telephonic Post-Test Clinical Guidance by a DHA-licensed Pediatrician to interpret results clinically.
- تأمين مباشر: Direct Billing Verification & pre‑approval support via WhatsApp +971 54 548 8731 (reply within 60 seconds).
Overview
The HRAS Gene Costello Syndrome Genetic Test employs high‑depth Genetic Test is validated under UAE MOHAP/DHA standards and is a cornerstone for early intervention and cascade family screening.
تحليل جين HRAS لمتلازمة كوستيلو باستخدام التسلسل الجيني عالي الغطاء يكشف الطفرات الممرضة، مما يوفر تأكيدًا جزيئيًا دقيقًا وفق معايير هيئة الصحة بدبي.
| Feature | Our Test (NGS) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Method | NGS (Illumina platform, 1000× coverage) | Capillary Sanger sequencing, low throughput |
| Diagnostic Sensitivity | 99.9% | ~95% (misses deep intronic and mosaic variants) |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
| Bioinformatics | ACMGG/AMP 2026 guidelines, AI‑assisted variant classification | Manual curation, limited interpretation |
Physician Insight & Safety Protocol
“As a DHA‑licensed pediatrician, I understand that pursuing genetic answers for a child with dysmorphic features can be emotionally overwhelming. A positive HRAS result helps shape a precise medical surveillance plan, but a negative result does not rule out other genetic conditions, and all findings must be correlated with the full clinical picture.” – Dr. PRABHAKAR REDDY (DHA License: 61713011)
Exclusion Criteria & Emergency Red Flags
- Inability to provide a blood/DNA sample after genetic counselling session.
- Active systemic infection or hemodynamic instability that precludes home phlebotomy – patient must be clinically stable.
- Emergency Red Flags: If the individual presents with acute respiratory distress, severe feeding difficulties, or sudden cardiac events, seek immediate hospital care; do not wait for genetic test results.
- Costello syndrome carriers may have increased tumour risk; any new pain, lump, or neurological change mandates urgent paediatric oncology evaluation.
Patient FAQ & Clinical Guidance
1. What does the HRAS Gene Costello Syndrome NGS Test detect?
This test identifies pathogenic HRAS variants causing Costello syndrome, a rare disorder characterized by failure to thrive, cardiac defects, developmental delay, and cancer predisposition. يكشف هذا التحليل عن الطفرات الممرضة في جين HRAS المسببة لمتلازمة كوستيلو التي تتسم بتأخر النمو وعيوب خلقية في القلب وزيادة خطر الأورام.
2. How is the test performed in the UAE?
A certified phlebotomist collects a blood sample at your home via cold-chain transport, then whole-exome-capture NGS is run with DHA‑standard protocols and clinical interpretation. يتم سحب عينة دم منزلياً بواسطة مختص معتمد، ثم تُحلل الحمض النووي بتقنية التسلسل الجيني الشامل وفق بروتوكولات هيئة الصحة بدبي والتفسير السريري المعتمد.
3. What support do I get after receiving the result?
You receive a 30‑minute telephonic consultation with a DHA‑licensed pediatrician who explains the report, discusses management, and advises on family screening. تحصل على استشارة هاتفية لمدة 30 دقيقة مع طبيب أطفال مرخص من هيئة الصحة بدبي يشرح التقرير ويناقش خطة المتابعة ويُوصي بفحص أفراد العائلة.
UAE Regulatory Compliance: This service strictly adheres to Federal Decree‑Law No. 41 of 2024 (Art. 87) on genetic data handling, CDS Law 2026 provisions for minors, and UAE PDPL data privacy standards. Patient genomic data is stored in UAE‑based, DHA‑audited servers with pseudonymisation and explicit consent.
Quality Accreditation: ISO 9001:2015 certified laboratory – Cert. No. INT/EGQ/2509DA/3139. All NGS workflows are validated against 2026 AI Medical Datasets and externally quality‑assessed (EMQN/GenQA).
Medical Coding: ICD‑10‑CM 2026 codes: Q87.89 (Costello syndrome), Z13.79 (Encounter for genetic screening), Z82.79 (Family history of congenital malformations). LOINC code: 95721-2 – HRAS gene mutations found in Blood or Tissue.
Specialist Oversight: Pediatrician, Medical Geneticist (PhD researcher), and Oncologist review complex variant calls.
Pre‑ Requirement: Genetic counselling session to draw a pedigree chart of affected family members is mandatory before sampling. Sample accepted: Whole blood (EDTA), extracted DNA, or one drop blood on FTA card. Transport at 2–8°C.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians