Test Price
2,800 AED✅ Home Collection Available
HPS3 Gene (Hermansky‑Pudlak Syndrome Type 3) Genetic Test in UAE | 2,800 AED
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Processing.
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM across all emirates.
Clinical Guidance: Telephonic Post-Test Clinical Guidance session with a Consultant Medical Geneticist included in the service.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The HPS3 Gene Genetic Test analyses the entire coding region of the HPS3 gene using Next‑Generation Sequencing to confirm or rule out Hermansky‑Pudlak syndrome type 3, an autosomal recessive disorder characterised by oculocutaneous albinism, platelet storage pool deficiency, and risk of pulmonary fibrosis. A detailed clinical history must be provided and a mandatory genetic counselling session is required to draw a pedigree of family members affected by the HPS3 gene mutation before sample collection.
| Feature | Our Test (Premium NGS) | Closest Alternative (Single‑Gene Sanger) |
|---|---|---|
| Precision | Greater than 99.9% analytical sensitivity; detects point mutations, small indels, copy‑number variants | High sensitivity for targeted regions, but limited scope |
| Method | Next‑Generation Sequencing (NGS) with full bioinformatics pipeline | Sanger sequencing – lower throughput, individual exon focus |
| Speed | 3 to 4 weeks (comprehensive analysis) | 2–4 weeks, but often requires multiple rounds |
| Sample | Blood, extracted DNA, or one drop blood on FTA card | Blood or extracted DNA |
Physician Insight & Safety Protocols
"As a Consultant Medical Geneticist managing inherited disorders, I recognise that confirming a molecular diagnosis for Hermansky‑Pudlak syndrome type 3 through HPS3 gene sequencing provides essential clarity for bleeding risk stratification, ophthalmologic surveillance, and pulmonary monitoring. It is critical that all genetic results are interpreted within the full clinical context; a positive finding requires correlation with physical exam and laboratory evidence, while a negative result in a strong clinical picture should prompt evaluation of other HPS subtypes."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Therapeutic Advisory
Do not discontinue or alter prescribed medications, especially antiplatelet or anticoagulant therapies, without explicit written instruction from your treating physician. Temporary suspension of certain drugs before blood collection must be medically supervised.
Exclusion Criteria & Red Flags
- Individuals without clinical suspicion or a positive family history should first seek genetic counselling through a qualified professional.
- Minors require documented parental or guardian consent in accordance with UAE Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Emergency red flags: sudden severe bleeding, acute vision loss, or unexplained widespread bruising require immediate presentation to the nearest emergency department.
Patient FAQ & Clinical Guidance
1. What does the HPS3 NGS test detect and why is it clinically important?
This test sequences the entire HPS3 gene to identify disease-causing mutations responsible for Hermansky-Pudlak syndrome type 3. It enables definitive diagnosis, carrier identification, and tailored management of bleeding tendency, ocular complications, and pulmonary fibrosis risk. A confirmed genetic result allows for precise family counselling and early intervention strategies.
2. How is the sample collected and what home service options exist across the UAE?
A certified phlebotomist collects a peripheral blood sample at your home, office, or our facility between 8 AM and 11 PM daily. VIP Mobile Phlebotomy and Temperature-Controlled Cold-Chain Home Collection are available across all emirates. Alternatively, pre-extracted DNA or a dried blood spot on an FTA card may be accepted following prior consultation.
3. When will results be ready and can I schedule a specialist discussion?
Results are delivered within 3 to 4 weeks through a secure online portal. A complimentary telephonic clinical guidance session with a Consultant Medical Geneticist is included to interpret findings, discuss inheritance patterns, and outline appropriate follow-up care for both the patient and family members.
4. Is genetic counselling mandatory before taking this test?
Yes, a mandatory genetic counselling session is required before sample collection. This session covers the implications of positive and negative results, the autosomal recessive inheritance pattern, and the potential impact on family members. A detailed pedigree of affected relatives must be drawn during the session.
UAE Regulatory & Data Privacy Adherence
This genetic testing service operates in full compliance with UAE federal legal frameworks for health data protection and patient privacy. All genetic and personal data are processed under the provisions of Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical procedures, including genetic counselling and informed consent, adhere to the standards set by Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE maintains ISO 9001:2015 certification and applies rigorous data encryption, access control, and audit trail mechanisms to safeguard your medical information.
Clinical & Logistical Metadata
| Test Name | HPS3 Gene (Hermansky‑Pudlak Syndrome Type 3) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 weeks |
| Sample Type / Matrix | Blood, extracted DNA, or one drop blood on FTA card |
| Methodology Used | Next-Generation Sequencing (NGS) |
| ICD-10-CM Code | E70.31 |
| LOINC Code | 82939-1 |
| DHA Facility License & Laboratory Address | DHA Facility License Number: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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