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Test Price

2,800 AED

✅ Home Collection Available

HBG2 Gene (Transient Neonatal Cyanosis) Genetic Test in UAE | 2800 AED

Executive Summary & Core Metrics

Test Price: 2,800 AED  |  Turnaround Time: 3–4 weeks  |  Methodology: Next-Generation Sequencing (NGS)  |  Sample Type: Peripheral blood (heel-prick or venous)
Home Collection: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (daily 8 AM–11 PM)
Clinical Precision: Full gene coverage for HBG2, detecting pathogenic variants and variants of uncertain significance (VUS).

Test Overview & Methodology

This Next‑Generation Sequencing test detects pathogenic HBG2 gene variants responsible for benign transient neonatal cyanosis, a self‑limiting hemoglobinopathy that resolves within months. The assay uses an ACMG‑aligned bioinformatics pipeline for comprehensive variant interpretation.

Feature Our Test (NGS) Closest Alternative (Sanger)
Diagnostic Precision Full gene coverage, pathogenic & VUS detection Single-variant or limited panel
Methodology NGS (ACMG‑aligned pipeline) Sanger (manual, lower throughput)
Turnaround Time 3–4 weeks 4–6 weeks
Cost 2,800 AED 1,200–1,800 AED (limited)

Physician Insight & Safety Protocols

“Transient neonatal cyanosis can cause considerable parental concern. This NGS test provides a definitive genetic answer, enabling clinicians to confidently diagnose and reassure families. All results must be correlated with clinical findings by the attending physician.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Advisory Note: Medication Warning

Do not discontinue any prescribed medication without consulting your doctor. This test does not replace emergency medical evaluation.

Safety Exclusion Criteria & Urgent Red Flags

  • Exclusion: Not indicated for otherwise healthy newborns without cyanotic episodes or hemoglobinopathy suspicion. Testing requires prior genetic counseling and signed informed consent (Federal Decree-Law No. 4 of 2016 on Medical Liability).
  • ER Red Flags: If your infant shows persistent severe cyanosis, respiratory distress, poor feeding, or lethargy, seek immediate emergency care—do not wait for genetic test results.

Patient FAQ & Clinical Guidance

1. What is the HBG2 gene and how does it cause transient neonatal cyanosis?

The HBG2 gene encodes fetal gamma‑globin; a promoter variant delays its silencing postpartum, temporarily elevating fetal hemoglobin and causing benign cyanosis.

2. Is the blood draw painful for my baby?

The test requires only a small heel‑prick or venous sample, so discomfort is minimal and lasts only a few seconds.

3. How long do results take and what does the report include?

Results are delivered in 3 to 4 weeks and provide mutation classification, clinical commentary, and tailored genetic counseling recommendations.

UAE Regulatory & Data Privacy Adherence

Compliance: This test operates in full alignment with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All specimens are processed under ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139). Pre‑genetic counseling and a signed pedigree are mandatory. For home collection (8 AM–11 PM) and direct insurance billing verification, contact WhatsApp +971545488731.

Clinical & Logistical Metadata

Test Name HBG2 Gene (Transient Neonatal Cyanosis) Genetic Test
Price (AED) 2,800 AED
Turnaround Time 3–4 weeks
Sample Type / Matrix Peripheral whole blood (heel-prick or venous) – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AM–11 PM
Methodology Used Next-Generation Sequencing (NGS), ACMG-aligned pipeline
ICD-10-CM Code Z13.71 (Encounter for genetic counseling and testing for abnormal gene)
LOINC Code 21665-1 (Genetic testing for a specific gene)
DHA Facility License & Laboratory Address License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE (Corporate: DNA Labs UAE)

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