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Test Price

2,800 AED

✅ Home Collection Available

HADH Gene 3‑Hydroxyacyl‑CoA Dehydrogenase Deficiency Genetic Test in UAE | 2,800 AED | DHA Approved

Executive Summary & Core Metrics

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified NGS Processing
  • Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection (Available daily 8 AM – 11 PM)
  • Clinical Guidance: Telephonic Post‑Test Clinical Correlation & Result Interpretation by DHA‑Licensed Genetic Specialist
  • Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731
✅ ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) | 🏛️ DHA Facility License: 1143 | 🔐 UAE PDPL & ICT Health Law Compliant

Test Overview & Methodology

This advanced Next‑Generation Sequencing (NGS) test analyzes the entire coding region of the HADH gene to detect pathogenic variants causing 3‑hydroxyacyl‑CoA dehydrogenase deficiency (SCHAD deficiency) — a rare autosomal recessive fatty acid oxidation disorder presenting with fasting hypoglycemia and hyperinsulinism. Turnaround time is 3–4 weeks, delivering clinically actionable results aligned with DHA genetic testing standards.

Feature Our Test (NGS) Closest Alternative (Single‑Gene Sanger)
Precision 99.9% accuracy for all coding exons & splice sites High accuracy but restricted to selected exons
Methodology NGS (Next‑Generation Sequencing) – CE‑IVD marked Sanger sequencing – lower throughput
Speed 3–4 weeks 2–3 weeks
Coverage Entire coding region + deep intronic boundaries Targeted exons only

Physician Insight & Safety Protocols

“As a DHA‑licensed consultant medical geneticist, I recognize the clinical complexity of suspected metabolic disorders. This NGS test offers high‑resolution detection of HADH variants; however, a negative result does not exclude all inborn errors of metabolism. Clinical correlation with metabolic biomarkers and specialist follow‑up is mandatory. Patients and families should never alter dietary or medication regimens without direct medical supervision.”

– Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403

Advisory: Medication & Diet Management

Do not discontinue prescribed medications, supplements, or specialized dietary plans (e.g., low‑fat, high‑carbohydrate regimens) without explicit guidance from your endocrinologist or metabolic specialist. Abrupt changes can precipitate metabolic decompensation.

Patient Safety Exclusion Criteria & Emergency Red Flags

  • Exclusion Criteria: Acute metabolic decompensation requiring emergency stabilization; inability to obtain valid informed consent (minors require guardian consent per UAE Federal Law); severely hemolyzed or contaminated samples will be rejected.
  • ER Red Flags: New onset of irritability, lethargy, seizures, or unexplained hypoglycemic episodes require immediate medical attention — do not wait for test results. Suspected hyperammonemic crisis demands urgent pediatric metabolic evaluation.

Patient FAQ & Clinical Guidance

1. What is the HADH gene test and why is it needed?

This NGS test sequences all coding regions of the HADH gene to detect mutations causing short‑chain 3‑hydroxyacyl‑CoA dehydrogenase deficiency, a rare metabolic disorder leading to fasting hypoglycemia and hyperinsulinism. It confirms the molecular diagnosis in symptomatic children or at‑risk siblings, guiding precise dietary management and emergency protocols.

2. How is the genetic sample collected and is home service available in the UAE?

A simple blood draw (whole blood in EDTA) or a finger‑prick on an FTA card can be collected by our DHA‑licensed, cold‑chain compliant mobile phlebotomy team at your home across Dubai, Abu Dhabi, Sharjah, and all Northern Emirates, 8 AM – 11 PM. The entire process takes under 10 minutes and samples are transported under strict temperature control to our ISO‑certified lab.

3. Is this test approved by DHA and covered by insurance?

Yes, the test is performed in a DHA‑licensed facility (license 1143) with ISO 9001:2015 certification and fully adheres to UAE PDPL genetic data privacy regulations. Most major UAE insurers cover this diagnostic when pre‑authorised; our team offers direct billing support and benefit verification via WhatsApp +971545488731.

UAE Regulatory & Data Privacy Adherence

Compliance Framework: All genetic data is handled in strict accordance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent are governed by Federal Decree‑Law No. 4 of 2016 on Medical Liability. Results are shared only with the ordering physician and the patient/guardian through secure, encrypted channels.

Clinical & Logistical Metadata

Test Name HADH Gene 3‑Hydroxyacyl‑CoA Dehydrogenase Deficiency Genetic Test (NGS)
Price (AED) 2,800 AED
Turnaround Time 3–4 Weeks
Sample Type / Matrix Whole Blood (EDTA) or FTA Card
Methodology Used Next‑Generation Sequencing (NGS) – CE‑IVD Marked
ICD‑10‑CM Code E71.3 (Disorders of fatty‑acid oxidation)
LOINC Code 81614‑3 (HADH gene mutation analysis in blood)
DHA Facility License & Address License 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE

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