Test Price
2,800 AED✅ Home Collection Available
GRN Gene Analysis (Ceroid Lipofuscinosis Neuronal Type 11, CLN11) – Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
- 99.9% Diagnostic Sensitivity – NGS executed under ISO 9001:2015 accredited processing.
- Premium Logistics – VIP mobile phlebotomy & temperature-controlled cold-chain home collection available daily 8 AM to 11 PM.
- Clinical Guidance – Telephonic post-test genetic counselling and result interpretation included.
- Insurance Support – Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This NGS assay targets the entire coding region of the GRN gene, the molecular cause of ceroid lipofuscinosis neuronal type 11 (CLN11). In the UAE, neurologists, medical geneticists, and general physicians depend on this test to confirm adult- or pediatric-onset neurodegenerative lysosomal storage disease and guide family planning.
| Feature | Our CLN11 NGS Test | Standard Single‑Gene Sequencing |
|---|---|---|
| Methodology | NGS (Illumina platform) – full gene coverage | Sanger sequencing – limited to known hotspots |
| Precision | 99.9% analytical sensitivity for SNVs/indels | ~95% for confined regions |
| Turnaround Time | 3‑4 weeks | 6‑8 weeks (outsourced) |
| Variant Interpretation | ACMG guidelines + clinical correlation | Basic report only |
| Sample Accepted | Whole blood, extracted DNA, or FTA card | Whole blood only |
Clinical Intent by Specialist: Neurologists – confirm CLN11 diagnosis and monitor neurodegeneration; Medical Geneticists – variant interpretation and reproductive counselling; General Physicians – initial suspicion and referral pathway.
Physician Insight & Safety Protocols
“As a consultant medical geneticist, I emphasize that GRN sequencing must always be interpreted in the context of neurological examination and family pedigree. The included genetic counselling session is essential for accurate variant interpretation and family risk assessment.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
⚠️ Medication Safety Advisory
Do not discontinue any prescribed medication without direct instruction from your treating physician.
⚠️ Pre-Test Exclusion Criteria
- Active febrile illness, hemodynamic instability, or inability to provide informed consent for genetic testing. A genetic counselling session with pedigree analysis is mandatory before sample collection.
- Emergency red flags: new-onset seizures, rapid loss of motor skills, visual hallucinations, or sudden behavioural regression require immediate neurological evaluation unrelated to test scheduling.
Patient FAQ & Clinical Guidance
1. What is the GRN gene test for ceroid lipofuscinosis type 11, and why is it recommended?
Snippet: The GRN gene test detects mutations causing CLN11, a neurodegenerative lysosomal disorder, enabling precise diagnosis and family risk assessment in the UAE.
2. Who needs to undergo this next‑generation sequencing test for CLN11?
Snippet: Individuals with progressive myoclonus, ataxia, or cognitive decline, as well as asymptomatic relatives with a known GRN family variant, require this NGS in the UAE.
3. How is the sample collected and what can I expect regarding turnaround time?
Snippet: A simple blood draw, DNA sample, or finger‑prick on an FTA card is collected via home phlebotomy, with results delivered in 3–4 weeks in the UAE.
UAE Regulatory & Data Privacy Adherence
This test is conducted in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent and safety are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. All clinical data are securely handled in accordance with DHA standards.
Clinical & Logistical Metadata
| Test Name | GRN Gene Analysis (Ceroid Lipofuscinosis Neuronal Type 11, CLN11) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Whole blood, extracted DNA, or FTA card |
| Methodology Used | Next-Generation Sequencing (NGS), Illumina platform, full gene coverage |
| ICD-10-CM Code | E75.4 |
| LOINC Code | 94842-2 |
| DHA Facility License & Laboratory Address | DHA Facility License Number: 1143 Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE Corporate Lab Branding: DNA Labs UAE |
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