Test Price
2,800 AED✅ Home Collection Available
GRIN2B Gene Sequencing for Mental Retardation, Autosomal Dominant Type 6 (Genetic Test) in UAE | 2800 AED | DNA Labs UAE
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: Hospital-Grade Home Collection with ISO Certified Cold-Chain Transport & VIP Mobile Phlebotomy (8 AM – 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Genetics Counselling by DHA-Licensed Consultant Medical Geneticist for result interpretation.
- Insurance: Direct Billing Verification via WhatsApp: +971 54 548 8731
This GRIN2B gene sequencing service provides definitive molecular diagnosis for autosomal dominant mental retardation type 6, enabling targeted early interventions and informed family planning. The test is performed under stringent ISO-accredited protocols with comprehensive post-result genetic counselling.
Test Overview & Methodology
The GRIN2B gene sequencing test identifies pathogenic variants associated with autosomal dominant mental retardation type 6 (MRD6), providing essential molecular diagnosis for personalised clinical management and family counselling. This targeted analysis employs next-generation sequencing with orthogonal Sanger confirmation to detect single nucleotide variants, small insertions/deletions, and clinically relevant copy number changes within the GRIN2B coding region and splice sites.
| Feature | Our Test (NGS + Sanger Confirmation) | Closest Alternative (Chromosomal Microarray) |
|---|---|---|
| Precision | Detects single nucleotide variants, indels, and small CNVs in GRIN2B with >99.9% analytical sensitivity | Only large deletions/duplications; misses point mutations causing MRD6 |
| Methodology | Targeted NGS (Next-Generation Sequencing) with bioinformatics pipeline & Sanger validation | Array CGH (Comparative Genomic Hybridization) |
| Turnaround | 3–4 Weeks | 2–3 Weeks (but lower diagnostic yield) |
Physician Insight & Safety Protocols
“As a Consultant Medical Geneticist, I recognise the profound emotional and medical journey families undertake when seeking a genetic diagnosis. This GRIN2B sequencing test is a critical tool for confirming autosomal dominant mental retardation type 6, but results must always be interpreted alongside a comprehensive clinical evaluation, three-generation pedigree analysis, and formal genetic counselling to guide appropriate early interventions. Please remember: do not adjust any existing therapies without direct medical consultation.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory: Medication Safety & Clinical Precautions
Do not discontinue prescribed medication (antiepileptics, psychotropics, or any ongoing therapy) without consulting your physician.
Exclusion Criteria & Emergency Red Flags
- Active bleeding disorder or therapeutic anticoagulation (adjust per physician advice before blood draw).
- Uncontrolled severe needle phobia without prior sedation arrangement.
- Minors lacking legal guardian consent (mandatory under Federal Decree-Law No. 4 of 2016 on Medical Liability).
- Seek emergency care immediately if the individual experiences new-onset seizures, sudden behavioural regression, loss of previously acquired developmental milestones, or signs of increased intracranial pressure.
Patient FAQ & Clinical Guidance
1. What is the purpose of the GRIN2B gene test in the UAE?
The GRIN2B gene test identifies pathogenic variants causing autosomal dominant mental retardation type 6, enabling early therapeutic interventions and accurate genetic counselling for families. This molecular diagnosis helps guide developmental support strategies, seizure management, and recurrence risk assessment for future pregnancies.
2. How should I prepare my child for this genetic blood test?
No fasting is required; ensure the child is well-hydrated. A mandatory pre-test genetic counselling session with pedigree chart construction must be completed prior to sample collection. Our mobile phlebotomist will coordinate a convenient home visit between 8 AM and 11 PM.
3. What is the turnaround time and the follow-up support after results?
Results are delivered within 3–4 weeks from sample receipt, followed by a dedicated telephonic clinical guidance session with our DHA-licensed Consultant Medical Geneticist to interpret findings and discuss reproductive options, family screening, and multidisciplinary care pathways.
UAE Regulatory & Data Privacy Adherence
Data Protection & Healthcare Compliance
DNA Labs UAE operates under DHA Facility License Number 1143 and adheres fully to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted, access-controlled, and processed exclusively within UAE borders. Patient consent and clinical safety protocols comply with Federal Decree-Law No. 4 of 2016 on Medical Liability. Our ISO 9001:2015 certification (INT/EGQ/2509DA/3139) guarantees rigorous quality management across every laboratory workflow.
Clinical & Logistical Metadata
| Test Name | GRIN2B Gene Sequencing for Mental Retardation, Autosomal Dominant Type 6 |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood (Peripheral Venous) – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AM – 11 PM |
| Methodology Used | Targeted Next-Generation Sequencing (NGS) with Sanger confirmation and bioinformatics variant interpretation |
| ICD-10-CM Code | F79 (Unspecified intellectual disabilities – primary code for autosomal dominant mental retardation type 6) |
| LOINC Code | 81261-2 (GRIN2B gene sequencing) |
| DHA Facility License & Laboratory Address | License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians