Test Price
2,800 AED✅ Home Collection Available
GNRHR Gene Hypogonadotropic Hypogonadism Type 7 with or without Anosmia Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Next‑Generation Sequencing (NGS) Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection conducted daily from 08:00 AM to 11:00 PM.
- Clinical Guidance: Dedicated telephonic post‑test result interpretation and counseling by our licensed clinical genetics team.
- Insurance & Billing: Direct billing verification and price transparency available via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The GNRHR gene sequencing test detects pathogenic variants causing hypogonadotropic hypogonadism type 7 (with or without anosmia). This NGS‑based analysis screens all coding exons and conserved splice junctions of the GNRHR gene, providing a definitive molecular diagnosis for delayed puberty, congenital infertility, and related reproductive endocrine disorders. The test achieves 99.9% analytical sensitivity for single nucleotide variants and small insertions or deletions.
| Feature | Our NGS Test (Precision / Method / Speed) | Closest Alternative (Hormonal Workup) |
|---|---|---|
| Methodology | Next Generation Sequencing (NGS) – Full gene coverage | Serial serum LH, FSH, testosterone / estradiol assays |
| Diagnostic Precision | Identifies exact genetic mutation; distinguishes specific subtypes | Functional only – cannot pinpoint genetic etiology |
| Turnaround Time | 3–4 weeks | Same day to several days |
| Cost (AED) | 2,800 (comprehensive, one‑time molecular analysis) | Variable – repeated visits, imaging, and dynamic testing required |
| Clinical Utility | Definitive diagnosis, family cascade screening, fertility planning | Initial screening – often leads to genetic testing for confirmation |
Physician Insight & Safety Protocols
"As a Consultant Medical Genetics specialist, I emphasize that the GNRHR gene test provides a definitive molecular diagnosis for hypogonadotropic hypogonadism type 7. Identifying the precise genetic mutation not only confirms the diagnosis but also opens the door for personalized treatment plans, family cascade testing, and informed reproductive decisions. It is essential to pair this powerful technology with comprehensive pre- and post‑test genetic counseling."
— Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
Medication Advisory & Clinical Safety
⚠️ Medication Advisory: Do not discontinue or alter any prescribed medications, including hormone replacement therapies (HRT) or gonadotropin therapy, without consulting your referring physician or endocrinologist. Abrupt changes can lead to significant health risks.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Individuals who have not completed a formal genetic counseling session and signed the informed consent form are excluded from testing. Patients under 18 years of age require consent from a legal guardian. This test is not intended for acute medical emergencies or unstable patients.
- Emergency Red Flags: If you experience sudden severe headache, visual disturbances, rapid hormonal changes (e.g., sudden breast development in males), or acute scrotal pain, call emergency medical services (998 in UAE) or visit the nearest emergency department immediately.
Patient FAQ & Clinical Guidance
1. What is the GNRHR gene test and why is it performed?
Key Point: The GNRHR gene test identifies mutations in the GNRHR gene responsible for hypogonadotropic hypogonadism type 7, a condition causing delayed puberty, infertility, and anosmia.
The test uses next‑generation sequencing to analyze the entire coding region, offering a definitive molecular diagnosis and aiding in personalized treatment planning, such as gonadotropin therapy or in vitro fertilization.
2. How is the sample collected and what are the requirements?
Key Point: A blood sample, extracted DNA, or a single drop of blood on an FTA card is required. Collection is offered via our secure home‑based VIP phlebotomy service with temperature‑controlled cold‑chain transport.
Prior to testing, a mandatory genetic counseling session is conducted to draw a pedigree and assess family history. Fasting is not required, and results are typically available within 3–4 weeks.
3. What do the results mean and what follow‑up is needed?
Key Point: A positive result confirms a genetic cause for hypogonadotropic hypogonadism, guiding personalized treatment such as gonadotropin therapy or fertility planning. A negative result requires further clinical evaluation.
All results include a telephonic consultation with our clinical team. If a mutation is found, relatives may also be offered cascade testing. Follow‑up with an endocrinologist is essential for comprehensive management.
UAE Regulatory & Data Privacy Adherence
- Data Protection: Fully compliant with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Medical Liability & Consent: Diagnostic protocols adhere to Federal Decree‑Law No. 4 of 2016 on Medical Liability, ensuring informed consent and patient safety standards.
- Quality Certification: ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139).
- Facility Licensing: All testing is conducted under the DHA Facility License Number 1143 at DNA Labs UAE, located in Dubai Healthcare City.
Clinical & Logistical Metadata
| Test Name | GNRHR Gene Hypogonadotropic Hypogonadism Type 7 with or without Anosmia Sequencing |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood, Extracted DNA, or FTA Card Dried Blood Spot |
| Methodology Used | Next Generation Sequencing (NGS) – Full Gene Coverage |
| ICD-10-CM Code | E23.0, R41.0 |
| LOINC Code | 82378-6 |
| DHA Facility License & Address | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | License: 1143 |
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