Test Price
2,800 AED✅ Home Collection Available
GLB1 Gene GM1-Gangliosidosis Genetic Test in UAE | 2,800 AED | DHA Licensed Laboratory
Executive Summary & Core Metrics
- Diagnostic Accuracy: 99.9% sensitivity for point mutations and copy number variants via validated NGS workflow (ISO 9001:2015 certified).
- Logistical Excellence: VIP Mobile Phlebotomy and temperature-controlled cold-chain home collection available daily 8 AM – 11 PM across all UAE emirates.
- Post-Test Medical Guidance: Complimentary telephone consultation with a Consultant Medical Geneticist to interpret results and discuss family planning.
- Insurance Facilitation: Direct coverage verification via WhatsApp +971 54 548 8731; claims support provided for major UAE insurers.
Test Overview & Methodology
This advanced Next‑Generation Sequencing (NGS) test sequences the entire GLB1 gene to detect pathogenic variants responsible for GM1‑gangliosidosis – a severe, progressive lysosomal storage disorder with neurodegeneration. Developed by medical geneticists and laboratory scientists, the assay delivers comprehensive molecular data critical for early diagnosis, carrier screening, and personalised management.
| Feature | Our GLB1 NGS Test | Closest Alternative (Sanger / Targeted) |
|---|---|---|
| Methodology | Next Generation Sequencing – full GLB1 gene | Sanger sequencing or limited hotspot panels |
| Diagnostic Sensitivity | 99.9% for point mutations and CNVs | ~95–98%; may miss large deletions |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks typical |
| Sample Type | Blood, Extracted DNA, or FTA DNA Card | Blood or DNA only |
| UAE Home Collection | ISO‑certified cold‑chain, 8 AM – 11 PM | Often unavailable |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA Registration ID: 9294403): “This GLB1 NGS test provides definitive molecular evidence for GM1‑gangliosidosis. However, results must always be interpreted alongside clinical presentation and family history. Pre‑ and post‑test genetic counselling is mandatory to ensure you understand inheritance risks and implications for relatives. Never alter any prescribed therapy without direct physician oversight.”
Advisory: Medication & Clinical Management
Important: Do not discontinue or modify any prescribed medication without consulting your treating physician. This genetic test is not a substitute for a comprehensive clinical evaluation and should not guide acute care decisions.
Exclusion Criteria & Safety Red Flags
- Exclusion Criteria: Inability to provide a blood, extracted DNA, or FTA card sample; active systemic infection at the time of collection.
- Pre‑test Requirement: A genetic counselling session to construct a pedigree chart of affected family members is mandatory for accurate interpretation.
- Emergency Red Flags: If you experience acute neurological deterioration, uncontrolled seizures, sudden loss of consciousness, or respiratory distress, seek emergency care immediately. This test does not provide real‑time results for crisis management.
Patient FAQ & Clinical Guidance
1. What does the GLB1 gene test diagnose?
The GLB1 NGS test identifies mutations responsible for GM1‑gangliosidosis, an inherited lysosomal storage disorder that causes severe neurological decline. The test detects point mutations and copy number variants across the entire gene.
2. How is the sample collected and what is the turnaround time?
A blood draw, extracted DNA sample, or FTA DNA card is collected. Our VIP Mobile Phlebotomy service provides home collection via cold‑chain logistics from 8 AM to 11 PM daily. Results are delivered within 3 to 4 weeks.
3. Is this test covered by insurance in the UAE?
Direct insurance coverage verification is available via WhatsApp at +971 54 548 8731. Our team assists with claim submissions for most major UAE health insurance plans.
4. Do I need to fast or prepare before the sample collection?
No special preparation is required. However, we recommend scheduling your genetic counselling session before the blood draw to ensure you fully understand the testing process and implications.
UAE Regulatory & Data Privacy Adherence
Your Data, Your Rights
DNA Labs UAE operates under the strict data protection framework of Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and complies with Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted, stored within the UAE, and never shared without explicit patient consent. Clinical testing adheres to Federal Decree‑Law No. 4 of 2016 on Medical Liability to ensure patient safety and informed consent.
Clinical & Logistical Metadata
| Test Name | GLB1 Gene GM1‑Gangliosidosis (NGS) |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Blood, Extracted DNA, or FTA DNA Card |
| Methodology Used | Next Generation Sequencing (NGS) – Full Gene |
| ICD‑10‑CM Code | E75.0 |
| LOINC Code | 81313-7 |
| DHA Facility License & Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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