Also known as: Krabbe Disease Genetic Test, Globoid Cell Leukodystrophy Genetic Test
Test Price
2,800 AEDโ Home Collection Available
๐ Results in 3โ4 Weeks
GALC Gene Krabbe Disease Genetic Test in UAE
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 certified processing.
- Premium Logistics: VIP Mobile Phlebotomy & temperature-controlled cold-chain home collection (available daily 8 AM โ 11 PM) across all UAE.
- Clinical Guidance: Telephonic post-test clinical guidance for result interpretation.
- Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
- Price: 2,800 AED (inclusive of full gene sequencing and counseling).
Test Overview & Methodology
This test sequences the entire GALC gene to identify pathogenic variants causing Krabbe disease (globoid cell leukodystrophy), a rare autosomal recessive metabolic disorder. Using next-generation sequencing (NGS) on the Illumina platform, it provides comprehensive coverage including copy number variant (CNV) analysis. The test is suitable for diagnostic confirmation, carrier screening, and presymptomatic testing in at-risk individuals.
| Feature | Our Test | Closest Alternative |
|---|---|---|
| Precision | Full gene NGS + CNV analysis; >99.9% analytical sensitivity | Targeted mutation panel (limited variants) |
| Method | Next-Generation Sequencing (NGS) on Illumina platform | Sanger sequencing of selected exons |
| Turnaround Time | 3โ4 Weeks | 4โ6 Weeks |
| Sample Types | Whole Blood, Extracted DNA, Dried Blood Spot (FTA Card) | Whole Blood only |
Physician Insight & Safety Protocols
โA positive result demands prompt neurological evaluation and genetic counseling. Even a negative resultโespecially in the presence of clinical symptomsโrequires careful correlation with biochemical markers like galactocerebrosidase enzyme activity. I strongly advise against making irreversible decisions based on this test alone without expert consultation.โ โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory โ Medication & Clinical Management
โ ๏ธ Important Notice
Do not discontinue any prescribed medication without consulting your doctor. Genetic test results are not a substitute for comprehensive clinical evaluation and management. Always correlate molecular findings with enzyme activity and clinical presentation.
Exclusion Criteria & Emergency Red Flags
- Not suitable as a standalone emergency diagnosis; acute neurological decline requires immediate hospital assessment.
- Testing of minors requires documented parental/guardian consent in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Results cannot be used for legal or immigration purposes without a formal court order.
- Seek urgent care if: sudden loss of motor skills, seizures, or coma develop before receiving test results.
Patient FAQ & Clinical Guidance
1. What does the GALC gene NGS test detect?
It identifies pathogenic DNA variants across the entire GALC gene, providing definitive molecular diagnosis for Krabbe disease, including carrier status. The test also detects copy number variations. A preliminary verbal result can be provided within 15 days.
2. How is the sample collected and what is the turnaround time?
We offer VIP mobile phlebotomy from 8 AM to 11 PM daily. Samples accepted include whole blood, extracted DNA, or dried blood spots (FTA card). Results are available within 3โ4 weeks. All logistics follow ISO-certified cold-chain protocols.
3. Is genetic counseling included and how do I interpret the results?
A mandatory pre-test genetic counseling session is conducted to draw a pedigree chart and discuss implications. Post-test, telephonic clinical guidance explains the results, next steps, and referral options. Interpretation always correlates with enzyme activity and clinical history.
UAE Regulatory & Data Privacy Adherence
This service adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent follow Federal Decree-Law No. 4 of 2016 on Medical Liability. The laboratory operates under DHA facility license 1143 (Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE) and is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139). All genetic data is processed and stored on UAE-secured servers.
Clinical & Logistical Metadata
| Test Name | GALC Gene Krabbe Disease Genetic Test (Full Gene NGS) |
| Price (AED) | 2,800 |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Whole Blood, Extracted DNA, Dried Blood Spot (FTA Card) |
| Methodology Used | Next-Generation Sequencing (NGS) on Illumina platform, including CNV analysis |
| ICD-10-CM Code | E75.23 (Globoid cell leukodystrophy) |
| LOINC Code | 94056-2 (GALC gene full sequence analysis) |
| DHA Facility License & Laboratory Address | License No. 1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
Book Your Test or Verify Insurance
WhatsApp: +971 54 548 8731 | Support available in English
Mobile Phlebotomy available in Dubai, Abu Dhabi, Sharjah, and all UAE.
ุฏุนู ุซูุงุฆู ุงููุบุฉ ู ุชุงุญ
ุงูุชุญูู ู ู ุงูุชุบุทูุฉ ุงูุชุฃู ูููุฉ
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
ุชููู ุนู ุงูุชุฎู ูู. ุฃุฑุณู ุตูุฑุฉ ู ู ุจุทุงูุฉ ุงูุชุฃู ูู ููุตูุฉ ุงูุทุจูุจ ุฅูู ูุฑูู ุงูุชุญูู ุงูู ุนุชู ุฏ ู ู ููุฆุฉ ุงูุตุญุฉ ุจุฏุจู ุนุจุฑ ุงููุงุชุณุงุจ. ุงุญุตู ุนูู ุชุญุฏูุซ ุงูุญุงูุฉ ูู ุฏูุงุฆู.
Available in Arabic, English, Hindi & Urdu
Preparation Required
["No specific fasting required", "No medication or diet restrictions"]
Medically Reviewed by Dr. Lina Osama Zaki Quteineh
All content reviewed by qualified professionals for accuracy.
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians