Test Price
2,800 AED✅ Home Collection Available
FSHB Gene (Follicle-Stimulating Hormone Beta Subunit) Deficiency – Isolated Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
Executive Summary: 99.9% diagnostic sensitivity through ISO-accredited next-generation sequencing. Premium home collection with temperature-controlled cold-chain logistics and telephonic post-test counselling. Direct insurance billing verification via WhatsApp.
- Accuracy Guarantee: 99.9% diagnostic sensitivity using ISO-accredited next‑generation sequencing.
- Premium Logistics: Paid hospital‑grade cold‑chain home collection & VIP mobile phlebotomy (8 AM – 11 PM).
- Clinical Guidance: Complimentary telephonic post‑test interpretation by certified genetic counsellors.
- Insurance: Direct billing verification via WhatsApp +971 54 548 8731 before your visit.
Test Overview & Methodology
The FSHB gene test sequences the entire coding region of the follicle‑stimulating hormone beta subunit, identifying pathogenic variants responsible for isolated FSH deficiency and consequent hypogonadotropic hypogonadism. This genetic confirmation allows precise family planning and personalised fertility treatment, avoiding years of trial‑and‑error therapies.
| Parameter | Our Test (NGS‑Based) | Closest Alternative (Hormonal Panel) |
|---|---|---|
| Diagnostic Precision | Full gene sequencing with copy number analysis | Indirect via serum FSH/LH levels; misses subclinical mutations |
| Methodology | Next Generation Sequencing (NGS) on Illumina platform | Immunoassay (ECLIA/ELISA) – cannot detect gene defects |
| Turnaround Time | 3–4 weeks, clinically actionable report | 2–5 days, but only phenotypic screening |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics at DNA Labs UAE, I emphasize that identifying a pathogenic FSHB variant does not automatically preclude fertility. Comprehensive reproductive endocrinology assessment and genetic counselling are essential to tailor appropriate assisted reproductive technologies or hormone replacement therapy. Never adjust prescribed medications without consulting your specialist.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
⚠️ Important: Do not discontinue any prescribed hormone therapy (estrogen, progesterone, testosterone, clomiphene, letrozole, gonadotropins) or fertility medications without consulting your physician. Abrupt cessation may cause ovarian hyperstimulation rebound, severe mood disturbances, or loss of therapeutic control.
Exclusion & Emergency Red Flags
- Exclusion: Active fever, acute infection, or recent blood transfusion (wait 4 weeks). Not suitable for patients under 18 years without court‑appointed guardian consent per Federal Decree-Law No. 4 of 2016 on Medical Liability.
- ER Red Flags: Severe abdominal pain, sudden vision loss, or signs of adrenal crisis (vomiting, confusion) after receiving results – seek immediate emergency care.
Patient FAQ & Clinical Guidance
1. Why is an NGS‑based FSHB gene test better than simple hormone blood tests?
Our method sequences the entire FSHB gene with 99.9% sensitivity, identifying mutations that hormone assays cannot detect. Standard FSH and LH blood tests measure circulating hormone levels that may be normal in heterozygous carriers or in early‑stage dysfunction, missing the genetic root cause. This genetic confirmation allows precise family planning and personalised fertility treatment, avoiding years of trial‑and‑error therapies.
2. What preparation is required for the test?
No fasting is required; the sample (whole blood or extracted DNA) can be collected any time after a mandatory genetic counselling session. You must provide a detailed medical history and family pedigree chart before the home visit technician arrives. The genetic counselling session is compulsory to ensure you understand the potential outcomes, and is conducted over the phone or in-home. We will contact you via WhatsApp to schedule.
3. How does insurance coverage work for this test?
DNA Labs UAE works with most major insurance companies in the UAE, and we provide direct coverage verification via WhatsApp. Before booking, send a photo of your insurance card to +971 54 548 8731 and we will respond within 30 minutes with the coverage percentage and pre-approval status. The UAE Personal Data Protection Law (PDPL) applies to all information transmitted.
UAE Regulatory & Data Privacy Adherence
Your data security is our priority. All personal health information is processed in accordance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical testing and patient consent procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE is fully licensed by the Dubai Health Authority under facility license number 1143.
Clinical & Logistical Metadata
| Test Name | FSHB Gene (Follicle-Stimulating Hormone Beta Subunit) Deficiency – Isolated Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Whole Blood (EDTA) or Extracted DNA |
| Methodology Used | Next Generation Sequencing (NGS) on Illumina platform |
| ICD-10-CM Code | E23.0 |
| LOINC Code | 21658-6 |
| DHA Facility License & Laboratory Address | DHA License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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