Test Price
2,800 AED✅ Home Collection Available
FLNA Gene Cardiac Valvular Dysplasia X-Linked Genetic Test in UAE
Executive Summary & Core Metrics
- 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified NGS Processing (Cert: INT/EGQ/2509DA/3139).
- VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection – Available daily from 8 AM to 11 PM.
- Post-Test Clinical Guidance – Complimentary telephonic result interpretation by a DHA-licensed consultant medical geneticist.
- Insurance Direct Billing – Verify your plan instantly via WhatsApp at +971 54 548 8731.
- Turnaround Time – 3 to 4 weeks from sample receipt to final clinically interpreted report.
Test Overview & Methodology
This advanced NGS test interrogates all coding exons, splice junctions, and deep intronic regions of the FLNA gene for pathogenic and likely pathogenic variants associated with X-linked cardiac valvular dysplasia. The analysis includes single-nucleotide variants (SNVs), small insertions/deletions (indels), and copy number variants (CNVs). Results are classified according to ACMG/AMP guidelines and integrated with echocardiographic correlation to enable precise risk stratification for index patients and cascade screening of at-risk family members.
| Feature | Our FLNA NGS Test | Closest Alternative (Single-Gene Sanger) |
|---|---|---|
| Target Coverage | 100% coding exons, splice sites, deep intronic variants | Selected exons only |
| Variant Detection | SNVs, indels, copy number variants (CNVs) included | Misses large deletions/duplications |
| Turnaround Time | 3–4 weeks | 6–8 weeks |
| Report | Clinically interpreted, ACMG-graded, with risk stratification | Raw variant list only |
Physician Insight & Safety Protocols
“A positive FLNA variant should never be interpreted in isolation; it must be correlated with comprehensive echocardiographic findings and a three-generation family pedigree. This molecular test is a powerful enabler for cascade screening in at-risk relatives, but definitive clinical management decisions require a multi-disciplinary team including a clinical geneticist and a cardiologist.” – Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Important Advisory
Do not discontinue, modify, or initiate any prescribed cardiac medication based solely on genetic test results without direct consultation with your treating physician.
Exclusion Criteria & Safety Considerations
- Patients with acute decompensated heart failure or hemodynamic instability should not delay emergency care for sample collection.
- This test is not suitable for pregnant individuals unless specifically ordered as part of a comprehensive prenatal genetic assessment.
- Minors (under 18 years) require written informed consent from a legal guardian, in full compliance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Inadequate sample quality (insufficient DNA, hemolysis, or degraded nucleic acid) may necessitate a repeat collection.
Emergency Warning: If you experience sudden chest pain, severe shortness of breath, or loss of consciousness, call 998 immediately and do not wait for test results.
Patient FAQ & Clinical Guidance
1. What is the FLNA genetic test, and how can it help my family?
This test identifies disease-causing mutations in the FLNA gene responsible for X-linked cardiac valvular dysplasia. A positive result enables early intervention, tailored surveillance, and cascade screening for at-risk female carriers and male relatives, potentially preventing life-threatening valvular complications.
2. Why does the test cost 2,800 AED and take 3 to 4 weeks?
The price reflects full-gene NGS sequencing, comprehensive CNV analysis, and a detailed clinical report reviewed by a DHA-licensed consultant medical geneticist. The turnaround time ensures rigorous bioinformatics processing, variant classification per ACMG standards, and clinical correlation with echocardiographic data.
3. Is home sample collection safe and approved for genetic testing?
Yes. Our DHA-licensed phlebotomists collect peripheral whole blood using ISO-certified temperature-controlled cold-chain kits that preserve DNA integrity from collection through laboratory receipt. This method yields reliability equivalent to in-clinic venipuncture and is fully approved for molecular genetic analysis.
4. Will my insurance cover this genetic test?
Coverage varies by insurer and plan. We offer direct billing support for many UAE health insurance policies. Send your policy details via WhatsApp to +971 54 548 8731 for a real-time eligibility check before proceeding with sample collection.
UAE Regulatory & Data Privacy Adherence
Your protected health information is handled in strict compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted, access-controlled, and processed within our Dubai Healthcare City facility under DHA License No. 1143. Clinical consent and safety protocols follow Federal Decree-Law No. 4 of 2016 on Medical Liability. No genetic information is shared with third parties without explicit written authorization from the patient or legal guardian.
Clinical & Logistical Metadata
| Test Name | FLNA Gene Sequencing & CNV Analysis for X-Linked Cardiac Valvular Dysplasia |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 weeks from sample receipt |
| Sample Type / Matrix | Peripheral whole blood (3–5 mL in EDTA lavender-top tube) – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM |
| Methodology Used | Next-Generation Sequencing (NGS) on Illumina platform with CNV calling; variant interpretation per ACMG/AMP 2015 guidelines |
| ICD-10-CM Code | Q24.8 |
| LOINC Code | 82993-5 |
| DHA Facility License & Laboratory Address | License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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