Test Price
2,800 AED✅ Home Collection Available
FGFR2 Gene Analysis for Jackson-Weiss Syndrome (Genetic Test) in Dubai, UAE
Executive Summary & Core Metrics
- ✓ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- ✓ Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection, 8 AM – 11 PM daily.
- ✓ Clinical Guidance: Telephonic Post-Test Clinical Guidance and Result Interpretation by a DHA-Licensed Consultant Medical Geneticist.
- ✓ Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The FGFR2 Next-Generation Sequencing (NGS) test identifies pathogenic variants in the FGFR2 gene causing Jackson-Weiss syndrome, a rare craniosynostosis-syndactyly disorder. This comprehensive analysis covers all coding exons and flanking splice regions, providing a molecular diagnosis that guides surgical planning and recurrence risk assessment. Compare our state-of-the-art UAE service with conventional alternatives:
| Feature | Our Test (NGS Panel) | Closest Alternative (Sanger Hotspots) |
|---|---|---|
| Precision / Coverage | Full gene sequencing, all coding regions ± 20 bp splice sites | Limited to 2-3 common hotspots; misses rare variants |
| Methodology | NGS on Illumina platform with bioinformatic ACMG interpretation | Capillary electrophoresis Sanger sequencing |
| Turnaround Time | 3 to 4 Weeks | 3 to 4 Weeks |
| Price (AED) | 2,800 | 3,500 - 4,000 |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA License: 9294403) shares: "As a clinical geneticist, I understand the profound implications of molecular diagnosis for craniosynostosis disorders. This FGFR2 NGS analysis provides definitive diagnostic clarity for Jackson-Weiss syndrome, which is essential for tailored neurosurgical planning and accurate family counselling. However, a negative result does not exclude other genetic causes of syndromic craniosynostosis, and results must always be interpreted within the full clinical and radiographic context."
Medication & Clinical Advisory
Do not discontinue, alter, or postpone any prescribed medications or treatments based on the results of this genetic test without explicit consultation with your referring physician or specialist. This molecular diagnostic test is an adjunct to, and not a replacement for, comprehensive clinical assessment and management.
Exclusion Criteria & ER Red Flags
- Inability to obtain an adequate blood spot or DNA sample due to severe peripheral circulatory compromise.
- Recent (< 2 weeks) allogeneic blood transfusion – may interfere with germline DNA interpretation.
- Patient or guardian unable to provide informed consent; a mandatory genetic counselling session is required prior to testing.
- Seek immediate emergency care if signs of raised intracranial pressure appear: projectile vomiting, extreme irritability, downward gaze (sunsetting eyes). This test is diagnostic; if acute craniosynostosis complications are suspected, go to the nearest ER.
Patient FAQ & Clinical Guidance
1. What is the FGFR2 NGS test for Jackson-Weiss syndrome and how can it help my child?
This advanced test sequences the FGFR2 gene to identify mutations causing Jackson-Weiss syndrome, a condition characterized by craniosynostosis and syndactyly. It enables a precise genetic diagnosis, guides essential surgical planning, and informs recurrence risk for family members. Early molecular confirmation can expedite referral to a specialized craniofacial team and prevent unnecessary investigations.
2. How is the sample collected and what are the preparation steps?
A small peripheral whole blood sample or previously extracted DNA is required. Our paediatric-trained phlebotomists utilize near-painless techniques for capillary or venous sampling, ensuring minimal discomfort for your child. A detailed clinical history and genetic counselling session are necessary to construct a comprehensive family pedigree. No fasting or medication changes are needed for the blood draw.
3. What is the turnaround time and how will I receive the results?
The standard turnaround time for complete FGFR2 gene sequencing and reporting is 3 to 4 weeks. Results are securely delivered via our encrypted digital health portal, followed by a telephonic consultation with a DHA-licensed consultant medical geneticist who will explain the clinical implications and recommended next steps in detail.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE strictly operates under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All clinical safety protocols and patient consent procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. Our facility is fully licensed by the Dubai Health Authority (DHA License: 1143) and accredited under ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | FGFR2 Gene Analysis for Jackson-Weiss Syndrome (NGS) |
| Price (AED) | 2,800 |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood or Extracted DNA |
| Methodology Used | Next-Generation Sequencing (NGS) – Illumina Platform, Full Gene Coverage ± 20 bp Splice Sites |
| ICD-10-CM Code | Q87.0 |
| LOINC Code | 91576-0 |
| DHA Facility License & Address | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DHA License: 1143 |
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