Test Price
2,800 AED✅ Home Collection Available
Factor XI Deficiency (F11) Gene Sequencing Test (NGS) in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
✓ Diagnostic Accuracy Guarantee: 99.9% analytical sensitivity and specificity for F11 gene variant detection via ISO 9001:2015 accredited NGS platform.
✓ Premium Home Collection: Complimentary hospital-grade, cold-chain home sample collection by DHA-licensed phlebotomists, 8 AM – 11 PM.
✓ Post-Test Clinical Guidance: Telephonic result interpretation by a genetic counselor, ensuring actionable clinical insights.
✓ Insurance Support: Direct billing verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
This NGS-based genetic test fully sequences the F11 gene to identify pathogenic variants responsible for hereditary factor XI deficiency, a rare bleeding disorder primarily characterized by prolonged bleeding after trauma or surgery. The analysis covers all coding exons and adjacent splice junctions with robust bioinformatics pipeline.
| Feature | Our Test (F11 NGS) | Closest Alternative |
|---|---|---|
| Precision | 99.9% analytical sensitivity/specificity | Sanger sequencing (~99%)—limited to coding regions only |
| Method | Full gene NGS (all exons, splice sites) | Targeted mutation panel or single‑exon Sanger |
| Turnaround | 3–4 weeks | 2–4 weeks (often requires multiple rounds) |
Physician Insight & Safety Protocols
“A F11 deficiency diagnosis must always be correlated with personal and family bleeding histories. One mutation may cause mild bleeding in some individuals and significant surgical bleeding in others; genetic results alone do not predict severity. Please engage your hematologist to integrate these findings into a tailored management plan.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
⚠ Medication Advisory
Do not discontinue or alter any prescribed medication without consulting your physician. Certain blood‑thinning agents (e.g., warfarin, DOACs) require careful management around genetic testing and procedural planning.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Active, uncontrolled bleeding; inability to provide informed consent; pregnancy (relative; requires specialist clearance).
- Seek urgent medical attention if you experience: sudden severe bleeding, blood in urine or stool, prolonged nosebleeds (>20 min), signs of intracranial bleeding (severe headache, vision changes, confusion).
Patient FAQ & Clinical Guidance
1. What does the F11 gene test detect?
This test analyzes the entire F11 gene using Next‑Generation Sequencing to identify mutations causing hereditary factor XI deficiency. The analysis covers all coding exons and adjacent splice junctions. Results are interpreted according to current ACMG guidelines and reported with clinical significance (pathogenic, likely pathogenic, VUS). A negative result does not exclude the presence of deep intronic variants or deletions/duplications that may require additional testing.
2. How should I prepare for the test?
A pre‑genetic counseling session is mandatory to draw a pedigree chart and discuss the implications of the results. No fasting is required for blood collection. If you are on anticoagulants, inform our team during scheduling. For FTA card samples, a single drop of blood is adequate. All samples are transported under strict cold‑chain (2‑8°C) to maintain DNA integrity.
3. Are results confidential and compliant with UAE law?
All genetic data is protected under UAE PDPL, processed inside DHA‑licensed facilities, and never shared without explicit written consent. The laboratory adheres to Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Results are delivered exclusively to the ordering physician or directly to the patient through secure encrypted channels. No information is disclosed to insurers or third parties without authorization.
UAE Regulatory & Data Privacy Adherence
This service is operated under DHA Facility License No. 1143 and complies with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139) guarantees quality management across all pre‑analytical, analytical and post‑analytical phases. Patient consent for genetic testing follows Federal Decree‑Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | Factor XI Deficiency (F11) Gene Sequencing Test |
| Price (AED) | 2800 |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Blood (EDTA), Extracted DNA, or FTA Card Blood Spot |
| Methodology Used | Next-Generation Sequencing (NGS) |
| ICD-10-CM Code | D68.1 |
| LOINC Code | 83142-5 |
| DHA Facility License & Laboratory Address | License 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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