Test Price
2,800 AED✅ Home Collection Available
F2 (Prothrombin) Gene Mutation Analysis (NGS) in UAE – 2,800 AED – DHCC Accredited
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 accredited processing (Cert: INT/EGQ/2509DA/3139).
Premium Logistics: VIP mobile phlebotomy & temperature-controlled cold-chain home collection (daily 8 AM to 11 PM).
Clinical Guidance: Complimentary telephonic post-test counselling with a consultant medical geneticist.
Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The F2 (Prothrombin) Gene Mutation Analysis employs next‑generation sequencing (NGS) to detect the G20210A variant, a well‑established inherited thrombophilia marker. This test offers single‑nucleotide resolution of the entire F2 gene, enabling precise risk stratification for venous thromboembolism.
| Feature | Our Test (NGS) | Closest Alternative (PCR) |
|---|---|---|
| Precision | Single‑nucleotide resolution, full gene coverage | Targeted mutation detection, limited to known hotspot |
| Method | Next‑Generation Sequencing (LC‑MS/MS validated) | Allele‑specific PCR |
| Speed | 3–4 Weeks (comprehensive analysis) | 1–2 Weeks |
Physician Insight & Safety Protocols
“I understand that genetic testing can be daunting. This test helps identify inherited thrombophilia risk but must be interpreted alongside your personal and family history. Always consult your haematologist for a comprehensive evaluation and follow‑up plan.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
Do not discontinue any prescribed anticoagulant medication without prior consultation with your physician. Genetic test results do not replace current therapy.
Safety Exclusion Criteria & Emergency Red Flags
- This test is not a stand‑alone diagnostic tool; genetic counselling is mandatory before sampling.
- Cannot be performed on patients with recent allogeneic bone marrow transplant (potential donor DNA interference).
- Emergency Red Flags: Sudden severe leg pain, unexplained chest pain, shortness of breath, or one‑sided limb swelling may indicate acute thrombosis. Seek immediate emergency care.
Patient FAQ & Clinical Guidance
1. What does a positive F2 prothrombin mutation result actually mean for my health?
A positive result indicates you carry one copy of the G20210A mutation, which increases your lifetime risk of venous thromboembolism by 3‑ to 5‑fold compared to the general population, but does not guarantee a clot will form. Lifelong preventive management under a haematologist is recommended.
2. How is the sample collected and what is the process?
A trained phlebotomist collects a simple blood sample during a scheduled home visit. The sample is transported via temperature‑controlled cold chain to our DHCC laboratory, where DNA is extracted and analysed using NGS. No special preparation is required.
3. When will I receive my results and how will they be explained?
Final reports are delivered within 3 to 4 weeks. A free telephonic counselling session with a consultant medical geneticist is included to explain every detail and guide you on next steps.
UAE Regulatory & Data Privacy Adherence
Compliance Framework
- Data Protection: Fully compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL).
- Health ICT Law: Adheres to Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Medical Liability: All clinical procedures and patient consent follow Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Accreditations: ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) and MOHAP Licensed: 9834453.
Clinical & Logistical Metadata
| Test Name | F2 (Prothrombin) Gene Mutation Analysis (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Peripheral whole blood (3–5 mL in EDTA tube) or dried blood spot (FTA card). VIP mobile phlebotomy & cold-chain home collection available daily 8 AM–11 PM. |
| Methodology Used | Next‑Generation Sequencing (NGS) with Sanger confirmation |
| ICD-10-CM Code | D68.51 (Primary hypercoagulable state due to prothrombin mutation) |
| LOINC Code | 59228-8 (Prothrombin gene mutation analysis) |
| DHA Facility License & Laboratory Address | DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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