Test Price
2,800 AEDโ Home Collection Available
F12 Gene (Factor XII Deficiency) Genetic Test in UAE | 2800 AED | DNA Labs UAE
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily 8 AM โ 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This NGS (Next-Generation Sequencing) test analyzes the entire F12 gene to identify pathogenic variants responsible for hereditary Factor XII deficiency and Hereditary Angioedema type III (HAE-FXII). It delivers a definitive molecular diagnosis crucial for personalized management and family screening.
| Parameter | Our Test (NGS F12 Gene) | Closest Alternative (Factor XII Activity Assay) |
|---|---|---|
| Precision | >99.9% analytical sensitivity & specificity | ~85-95% sensitivity; may miss functional mutations |
| Method | NGS (Next-Generation Sequencing) covering full gene | Functional clotting assay (aPTT-based) |
| Speed | Results in 3-4 Weeks | 1-2 Days |
| Clinical Utility | Identifies exact mutation, carrier status, HAE type III risk | Measures coagulation activity only, cannot distinguish genetic subtypes |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403 โThis NGS assay for the F12 gene provides a definitive genetic diagnosis for patients with unexplained prolonged aPTT or suspected hereditary angioedema. Identifying the exact mutation enables tailored management, family screening, and informed reproductive decisions. I recommend correlating all results with a thorough clinical assessment by a specialist in coagulation disorders.โ
Advisory
Medication Warning: Do not discontinue any prescribed anticoagulant or other medication without consulting your doctor. Genetic test results should be interpreted in the context of the patient's full clinical picture.
Patient Safety: Exclusion Criteria & ER Red Flags
- Exclusion Criteria: Recent blood transfusion (<3 months) may interfere with DNA purity; active systemic infection; inability to provide informed consent for genetic testing. Consultation with a genetic counsellor is mandatory before sample collection.
- ER Red Flags: If you experience sudden swelling of the lips, tongue, throat, difficulty breathing, or severe abdominal pain (possible angioedema attack), seek emergency medical care immediately. Chest pain, leg swelling, or shortness of breath warrant urgent evaluation for thrombosis.
Patient FAQ & Clinical Guidance
1. What is the F12 Gene NGS Test and why is it performed?
Answer: This genetic test sequences the F12 gene to detect mutations causing Factor XII deficiency or hereditary angioedema type III, providing a definitive diagnosis that guides lifelong care and family screening.
2. How long do results take, and what is the process for home sample collection?
Answer: Results are typically ready within 3 to 4 weeks; we offer VIP mobile phlebotomy and temperature-controlled cold-chain home collection available daily from 8 AM to 11 PM. Schedule an appointment easily via WhatsApp.
3. Is this test covered by insurance in the UAE, and what regulations apply?
Answer: Our service facilitates direct insurance billing verification through WhatsApp. We comply with UAE Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates under the oversight of the Dubai Health Authority (DHA) and adheres strictly to all federal data protection laws including Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent for genetic testing follows the provisions of Federal Decree-Law No. 4 of 2016 on Medical Liability. All test results are encrypted, and access is restricted to authorized medical personnel only.
Clinical & Logistical Metadata
| Test Name | F12 Gene Sequencing (Next-Generation Sequencing) |
| Price (AED) | 2,800 |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood |
| Methodology Used | Next-Generation Sequencing (NGS) |
| ICD-10-CM Code | D68.2, E88.0 |
| LOINC Code | 21636-3 |
| DHA Facility License & Laboratory Address | License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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