Test Price
2,800 AED✅ Home Collection Available
ESR1 Gene Estrogen Resistance Genetic Test in UAE – AED 2800 – DHA Approved
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 15189 & ISO 9001:2015 Certified Processing, with comprehensive NGS coverage of all ESR1 coding regions.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Post-test telephonic result interpretation by DHA-licensed genetic counsellors.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
- Compliance: Fully aligned with UAE Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
Test Overview & Methodology
The ESR1 Gene Estrogen Resistance Genetic Test uses Next-Generation Sequencing (NGS) to detect pathogenic variants in the ESR1 gene associated with estrogen resistance. This condition can profoundly impact bone health, growth, and reproductive development. The test provides a definitive molecular diagnosis to guide endocrinologists in personalised therapy and family planning.
| Feature | Our ESR1 NGS Test (AED 2,800) | Closest Alternative (Sanger Sequencing Panel) |
|---|---|---|
| Methodology | NGS – full gene coverage | Sanger Sequencing – limited to known hotspots |
| Diagnostic Sensitivity | 99.9% (captures novel & rare variants) | ~85% (misses intronic/regulatory mutations) |
| Turnaround Time | 21–28 Business Days | 6–8 Weeks |
| Pre-test Genetic Counselling | Included (pedigree chart construction) | Often not standard |
Physician Insight & Safety Protocols
Consultant Medical Genetics Lina Osama Zaki Quteineh (DHA Registration ID: 9294403) advises: “A positive ESR1 variant requires careful clinical correlation with the patient’s phenotype—bone age, growth velocity, and pubertal milestones—before considering any therapeutic intervention. This test is a powerful tool but must be interpreted within the full family history and endocrine work‑up. I urge patients to discuss all results with their specialist and never self‑adjust hormonal or supplementation regimens.”
Medication Advisory
Important Notice
“Do not discontinue prescribed medication without consulting your doctor.”
Adjusting estrogen, hormone replacement, or bone‑related therapies solely based on genetic results can be dangerous. Any change must be supervised by your treating physician.
Patient Safety & Exclusion Criteria
- Exclusion Criteria: Acute febrile illness, recent blood transfusion (within 2 weeks), ongoing chemotherapy that interferes with DNA quality, inability to provide informed consent (including minors without legal guardian consent as per UAE PDPL and Federal Law No. 2 of 2019).
- ER Red Flags – seek immediate medical attention: Sudden severe bone pain, unexplained fractures, rapid height increase with delayed puberty, severe headaches with visual disturbances.
- All genetic testing is safeguarded under UAE Federal Decree-Law No. 45 of 2021 (PDPL); your data is de‑identified and stored securely. Minors require explicit parental consent and genetic counselling.
Patient FAQ & Clinical Guidance
1. What does the ESR1 gene test reveal, and how can it help me?
The ESR1 NGS test detects pathogenic variants in the estrogen receptor alpha gene, clarifying the genetic cause of estrogen resistance for targeted clinical management. It identifies mutations that may explain tall stature, delayed bone maturation, metabolic irregularities, or unexplained infertility, enabling endocrinologists to tailor hormone therapy, monitor bone health, and guide family planning decisions.
2. How is the test performed and what is the turnaround time?
A simple blood draw is all that is required, with results available within 21–28 business days. Our VIP phlebotomy team visits your home (8 AM–11 PM) using a cold‑chain certified kit. The sample is processed by NGS in our ISO 15189‑accredited facility, ensuring comprehensive analysis of all ESR1 coding regions.
3. Who should consider taking an ESR1 gene test?
Individuals with a family history of estrogen resistance, unexplained tall stature, delayed puberty, or recurrent bone fragility are prime candidates for this genetic analysis. Additionally, endocrinologists, fertility specialists, and anti‑aging physicians may recommend it for adults exploring personalised hormone optimisation or for legal cases requiring genetic evidence of pubertal delay.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates under DHA Facility License Number 1143 and is fully compliant with the following UAE federal regulations:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – protecting the confidentiality and security of your health information.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – governing digital health records and telemedicine.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – ensuring patient safety and informed consent for clinical procedures and genetic testing.
Our laboratory is ISO 15189 and ISO 9001:2015 certified, and all genetic data is de‑identified, encrypted, and stored in secure servers within the UAE.
Clinical & Logistical Metadata
| Test Name | ESR1 Gene Estrogen Resistance Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 21–28 Business Days |
| Sample Type / Matrix | Peripheral Whole Blood |
| Methodology Used | Next-Generation Sequencing (NGS) |
| ICD-10-CM Code | Z15.89 (Encounter for genetic susceptibility to other disease) |
| LOINC Code | 93026-2 (ESR1 gene mutations found in Blood by Sequencing) |
| DHA Facility License & Laboratory Address | Facility License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
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