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Test Price

2,800 AED

✅ Home Collection Available

EOGT Gene Adams-Oliver Syndrome Type 4 Genetic Test

Executive Summary & Core Metrics

Diagnostic Accuracy: 99.9% analytical sensitivity and specificity via high-coverage Next-Generation Sequencing (NGS) with Sanger confirmation. Certified under ISO 15189 and DHA quality standards.

Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection – available daily from 8 AM to 11 PM. No hospital visit required for standard blood draw.

Clinical Guidance: Post-test telephone consultation with a Consultant Medical Geneticist to interpret results and coordinate cascade testing.

Insurance Verification: Direct confirmation via WhatsApp at +971 54 548 8731.

Test Overview & Methodology

The EOGT Gene Genetic Test utilises high-coverage Next-Generation Sequencing to interrogate the entire coding region and canonical splice sites of the EOGT gene, delivering definitive identification of pathogenic or likely pathogenic variants causative of Adams-Oliver syndrome type 4 (AOS4). This advanced molecular assay is the cornerstone for accurate diagnosis, family planning, and tailored clinical surveillance.

Feature Our Test – UAE Reference NGS Closest Alternative (Standard Panel)
Precision >99.9% analytical sensitivity & specificity; full gene CNV detection ~95% sensitivity, limited CNV analysis
Methodology NGS with 300x mean coverage, Sanger confirmation of pathogenic calls Targeted gene sequencing with lower depth
Turnaround Time 3-4 Weeks (expedited reporting available) 4-6 Weeks

Physician Insight & Safety Protocols

“The EOGT NGS test is a powerful confirmatory tool for Adams-Oliver syndrome type 4. However, its interpretation must always be integrated with the full clinical picture—genetic results alone do not exclude non-genetic phenocopies. A thorough physical examination and detailed family history remain essential. If a pathogenic variant is identified, please consult our genetic counsellor for cascade testing and prophylactic management.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA Registration ID: 9294403)

Advisory Guidance

Pre-Test Counselling Recommended

This test should only be ordered after formal genetic counselling. It is not a standalone screening tool. Patients must understand the implications of incidental findings, variant of unknown significance (VUS) results, and the potential need for family segregation studies.

Exclusion Criteria & Red Flags

Patient Safety – Contraindications

  • Exclusion: Active infection at planned venipuncture site; history of severe adverse reaction to phlebotomy.
  • Red Flag: Sudden worsening of scalp defects, new limb pain, or neurological symptoms warrant immediate emergency evaluation—do not await genetic results.
  • Not indicated for asymptomatic individuals without suggestive family history or clinical phenotype, unless part of a formal genetic counselling plan.

Patient FAQ & Clinical Guidance

1. What exactly does the EOGT gene test detect?

This test sequences the full coding region and splice sites of the EOGT gene to identify pathogenic variants that cause Adams-Oliver syndrome type 4, offering a definitive molecular diagnosis.

2. How is the sample collected and is a hospital visit required?

Our DHA-licensed phlebotomist visits your home between 8 AM and 11 PM for a simple blood draw, or you may submit pre-extracted DNA; no hospital visit is needed.

3. Who should consider this genetic test?

Anyone with clinical features of Adams-Oliver syndrome (scalp cutis aplasia, limb defects) or a family history, after genetic counselling, should consider this.

4. What is the turnaround time for results?

Typical turnaround is 3-4 weeks from sample receipt. Expedited reporting is available upon request.

UAE Regulatory & Data Privacy Adherence

Data Privacy: All genetic data is processed and stored in compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.

Accreditation: ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) | DHA Facility License: 1143 | Laboratory Premises: Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.

Clinical & Logistical Metadata

Test Name EOGT Gene Adams-Oliver Syndrome Type 4 Genetic Test (NGS)
Price (AED) 2,800 AED
Turnaround Time 3-4 Weeks (expedited available)
Sample Type / Matrix Peripheral whole blood (or pre-extracted DNA) – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection
Methodology Used Next-Generation Sequencing (NGS) with 300x mean coverage, Sanger confirmation of pathogenic variants
ICD-10-CM Code Q87.2 (Adams-Oliver syndrome), Q84.8 (Other specified congenital malformations of integument), Z13.79 (Encounter for genetic screening for other congenital anomalies)
LOINC Code 95887-3 (EOGT gene mutations found)
DHA Facility License & Laboratory Address DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE

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