Test Price
2,800 AED✅ Home Collection Available
DYRK1A Gene Sequencing (Autosomal Dominant Intellectual Disability 7)2,800 AED
Executive Summary & Core Metrics
🎯99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Processing (Cert: INT/EGQ/2509DA/3139).
🏠Premium Home Collection: Hospital-grade phlebotomy with cold-chain logistics compliant with UAE PDPL.
📞Post-Test Telephonic Guidance with DHA-certified clinical specialists to interpret results.
💳Insurance Verification: Direct Billing via WhatsApp +971 54 548 8731
Test Overview & Methodology
This advanced Next-Generation Sequencing (NGS) test precisely analyzes the DYRK1A gene to confirm or rule out Autosomal Dominant Intellectual Disability type 7 (MRD7). We utilize whole-gene sequencing with CNV detection, ensuring no pathogenic variant is missed.
| Feature | DNA Labs UAE NGS Test | Standard CMA/Microarray |
|---|---|---|
| Resolution | Single Nucleotide Variants (SNVs), Indels, and CNVs at 100x depth | Macro-deletions/Duplications only (misses SNVs) |
| Bioinformatics | AI-driven variant classification (ACMG/AMP) | Manual/Static baseline mapping |
| Turnaround Time | 3 to 4 Weeks | 4 to 8 Weeks |
Physician Insight & Safety Protocols
As a medical geneticist, I understand the journey families face when seeking answers for neurodevelopmental delays. The DYRK1A sequencing test offers precise diagnosis for autosomal dominant intellectual disability 7, guiding tailored interventions. However, a negative result does not exclude other genetic causes; comprehensive clinical correlation with a pediatric neurologist is essential for optimal management.
Advisory: Medication Continuation
Do not discontinue prescribed antiepileptic drugs (AEDs), neuroleptics, or any current medication without consulting your supervising physician, as this may provoke severe neurological manifestations.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Patients who have received a heterologous blood transfusion within the last 30 days may require rescheduling to avoid DNA cross-contamination.
- Red Flag: If the patient presents with sudden acute regression, status epilepticus, or loss of ambulation, proceed to the ER immediately. Genetic testing is for chronic, not acute, assessment.
- Minor Consent: For patients under 18, explicit legal guardian consent is required per Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA data is further secured under UAE PDPL.
Patient FAQ & Clinical Guidance
1. Why is NGS superior to older methods for detecting DYRK1A-related disorders?
NGS captures SNVs, indels, and CNVs across the entire DYRK1A coding region in a single assay, unlike CMA which misses point mutations. This results in higher diagnostic yield.
2. What does the VIP mobile phlebotomy home collection service entail in Dubai and Abu Dhabi?
Our ISO-certified nurses perform a hospital-grade blood draw or buccal swab at your home between 8 AM and 11 PM, with immediate cold-chain transport to our DHA-licensed laboratory to preserve DNA integrity.
3. How is my genetic data protected under UAE law?
Your genetic data is anonymized, encrypted, and stored onshore in compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 on Health ICT. No unauthorized access is permitted.
UAE Regulatory & Data Privacy Adherence
Data Protection: All genetic and personal data handled under this test is governed by Federal Decree-Law No. 45 of 2021 (PDPL) and Federal Law No. 2 of 2019 on the Use of Information and Communication Technology in Health Fields. Your results are accessible only to you and your designated physician.
DHA Compliance: DNA Labs UAE operates under DHA Facility License No. 1143, adhering to all mandatory clinical governance and data sovereignty requirements.
Clinical & Logistical Metadata
| Test Name | DYRK1A Gene Sequencing (Autosomal Dominant Intellectual Disability 7) |
| Price (AED) | 2,800 |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA) or Buccal Swab (FTA Card) – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection Available Daily 8 AM to 11 PM |
| Methodology Used | Next-Generation Sequencing (NGS) with Whole-Gene Sequencing and CNV Detection |
| ICD-10-CM Code | F78 (Other Intellectual Disabilities), R41.83 (Other Cognitive Impairment) |
| LOINC Code | 104621-5 (DYRK1A gene targeted mutation analysis) |
| DHA Facility License & Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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