Test Price
2,800 AED✅ Home Collection Available
DSPP Gene Dentinogenesis Imperfecta Shields Type 2 Genetic Test – Accurate NGS Analysis in Dubai, UAE
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
Clinical Guidance: Telephonic Post‑Test Guidance in Result Interpretation by DHA‑Licensed Genetics Expert.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The DSPP Gene Genetic Test detects pathogenic variants in the DSPP gene associated with dentinogenesis imperfecta Shields type 2, aiding in definitive diagnosis and genetic counselling. This comprehensive analysis utilises next‑generation sequencing (NGS) to examine the entire coding region, deep intronic segments, and copy‑number variations, delivering a diagnostic sensitivity of 99.9%. The test is ordered by clinical geneticists, paediatric dentists, and dermatologists to confirm a suspected diagnosis, differentiate from other dental genetic disorders, and provide essential information for family risk assessment and tailored treatment planning.
| Feature | Our Test (Premium Panel) | Standard Alternative (Targeted Sanger) |
|---|---|---|
| Methodology | NGS (Next‑Generation Sequencing) – comprehensive full‑gene analysis | Sanger sequencing of selected hotspots only |
| Diagnostic Sensitivity | 99.9% (includes deep intronic and copy‑number variants) | <95% – may miss rare or novel variants |
| Turnaround Time | 3 to 4 Weeks | 4 to 6 Weeks |
| Clinical Support | Post‑test telephone guidance with DHA‑licensed genetic counsellor | Written report only |
| Price | 2800 AED | 2500 – 3500 AED (variable) |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics specialist, I recognise that a genetic diagnosis of dentinogenesis imperfecta Shields type 2 can raise important questions about inheritance and long‑term dental management. This NGS‑based test provides the molecular clarity needed to confirm the diagnosis, distinguish it from other dental anomalies, and guide family counselling. The result must always be interpreted alongside clinical findings and discussed with a dentofacial specialist. Your care pathway is a collaborative effort, and we remain available to support you throughout the process.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Safety Advisory
Do Not Alter Prescribed Treatments Without Medical Guidance
Genetic test results are a diagnostic aid, not a replacement for ongoing clinical management. Continue all current medications and therapies as directed by your treating physician. Any changes to your treatment plan must be made in consultation with a qualified healthcare provider.
Safety Exclusion Criteria & Emergency Red Flags
When This Test Is Not Appropriate
- Exclusion: This test is not intended for emergency diagnostic use. It is not a standalone prenatal screening tool and must be accompanied by comprehensive genetic counselling. For minors under 18 years, parental or guardian consent is required in accordance with UAE Federal Decree-Law No. 4 of 2016 on Medical Liability.
- ER Red Flags: If you or your child experiences sudden severe dental pain, odontogenic infection with facial swelling, traumatic tooth fracture, or locked jaw, seek immediate dental emergency care or visit the nearest Emergency Department.
Patient FAQ & Clinical Guidance
1. What is the DSPP gene test for?
Concise Clinical Answer: This NGS‑based test identifies disease‑causing variants in the DSPP gene, confirming a diagnosis of dentinogenesis imperfecta Shields type 2 and enabling informed genetic counselling. It analyses the entire coding region, intronic boundaries, and copy‑number changes to maximise detection. The result helps your dentist plan restorative care, guide orthodontic timing, and allows family members to assess their own risk through cascade testing.
2. How is the sample collected?
Concise Clinical Answer: A peripheral whole blood sample (EDTA tube), extracted DNA, or a single blood spot on an FTA card is collected by our VIP mobile phlebotomy team at your home between 8 AM and 11 PM daily. All samples are transported under temperature‑controlled cold‑chain conditions to preserve nucleic acid integrity. The FTA card option is particularly suitable for paediatric patients or individuals with needle anxiety.
3. What does a positive result mean?
Concise Clinical Answer: A positive result indicates a pathogenic variant in the DSPP gene, confirming dentinogenesis imperfecta Shields type 2. This finding validates the clinical diagnosis and provides a basis for recurrence risk counselling. A negative result does not exclude other genetic or environmental causes and should be discussed with a genetic counsellor for complete interpretation.
UAE Regulatory & Data Privacy Adherence
Legal & Accreditation Framework
Data Protection: All personal and genetic data are processed in compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent, data minimisation, and secure storage protocols are strictly enforced.
Quality Accreditation: ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139) – every step from specimen collection through cold‑chain logistics to bioinformatic analysis and reporting meets international quality standards.
Clinical & Logistical Metadata
| Test Name | DSPP Gene Dentinogenesis Imperfecta Shields Type 2 Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA), Extracted DNA, or FTA Card Blood Spot |
| Methodology Used | Next‑Generation Sequencing (NGS) – Full Gene, Intronic & Copy‑Number Analysis |
| ICD-10-CM Code | K00.5, Z13.71, Z15.89 |
| LOINC Code | 93382-9 |
| DHA Facility License & Laboratory Address | License 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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