Test Price
2,800 AEDโ Home Collection Available
DSPP Gene Dentin Dysplasia Type 2 NGS Genetic Test in Dubai & UAE | 2800 AED
Executive Summary & Core Metrics
Comprehensive Genetic Analysis for Hereditary Dentin Disorders
- Diagnostic Precision: 99.9% analytical sensitivity and specificity via Next-Generation Sequencing (NGS) for definitive molecular diagnosis of Dentin Dysplasia Type 2 and Dentinogenesis Imperfecta.
- Logistics & Accessibility: VIP Mobile Phlebotomy and temperature-controlled cold-chain home collection available daily from 8 AM to 11 PM across Dubai and the UAE.
- Clinical Support: Complimentary pre- and post-test genetic counselling session with a certified specialist to interpret your results and guide management decisions.
- Billing & Insurance: Direct billing verification and support via WhatsApp at +971 54 548 8731.
Price (Inclusive of VAT)
2,800 AED
Turnaround Time
3 โ 4 Weeks
Sample Type / Matrix
Whole Blood (EDTA), Extracted DNA, or FTA Card
Test Overview & Methodology
The DSPP Gene Dentin Dysplasia Type 2 NGS Test provides comprehensive sequencing of the DSPP gene, which encodes dentin sialophosphoprotein. Pathogenic variants in DSPP are responsible for hereditary opalescent dentin, Dentin Dysplasia Type 2, and occasionally broader osteo-dermatological-immunological manifestations. This test employs targeted next-generation sequencing (Illumina platform) to detect point mutations, small insertions/deletions, and copy number variations with over 99.9% accuracy.
| Feature | Our NGS Test | Standard Sanger Sequencing |
|---|---|---|
| Methodology | NextโGeneration Sequencing (Illumina) | Sanger Sequencing |
| Analytical Sensitivity | โฅ 99.9% | ~ 98% |
| CNV Detection | Yes (Bioinformatics pipeline) | Limited |
| Turnaround Time | 3 โ 4 Weeks | 4 โ 6 Weeks |
Physician Insight & Safety Protocols
โA precise molecular diagnosis for Dentin Dysplasia Type 2 is pivotal not only for dental prognosis but also for identifying potential syndromic associations involving the skin and immune system. Our multidisciplinary approach integrates comprehensive genetic counselling to empower patients and their families with a clear understanding of inheritance patterns and clinical surveillance strategies.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA Registration ID: 9294403)
Medication & Pre-Test Advisory
Important Medication Warning
Do not discontinue any prescribed medication or alter your treatment regimen without prior consultation with your referring physician. Certain medications may affect test results or pose risks during sample collection.
Exclusion Criteria & Safety Red Flags
- Contraindications: Testing cannot proceed if the patient has an acute febrile illness, an active bleeding disorder, or has received a whole blood transfusion within the last 4 weeks.
- Mandatory Counselling: Pre-test genetic counselling is mandatory for all patients. A pedigree analysis session will be scheduled prior to sample collection to ensure informed consent.
- Emergency Red Flags: If you experience severe pain, persistent bleeding from the venipuncture site, a generalized rash, or difficulty breathing after sample collection, seek emergency medical attention immediately.
Patient FAQ & Clinical Guidance
1. What does a positive DSPP gene mutation mean for my dental health and overall condition?
A positive DSPP mutation confirms a diagnosis of hereditary dentin dysplasia type II or dentinogenesis imperfecta. This predisposes you to dental anomalies such as discolored, translucent, or brittle teeth. In some cases, it may associated with skin or immune system issues, necessitating a multidisciplinary follow-up with your dentist, geneticist, and primary care physician.
2. How accurate is the NGS technology for detecting DSPP gene variants?
Our NGS-based test delivers over 99.9% analytical sensitivity and specificity. It reliably identifies point mutations, small insertions and deletions, and copy number variations within the DSPP gene. This level of precision makes it the gold standard for molecular confirmation of dentin dysplasia disorders.
3. Is genetic counselling required before taking this test?
Yes, pre-test genetic counselling is mandatory to ensure you fully understand the implications of test results, including inheritance patterns and potential family impacts. Our service includes a dedicated session with a certified genetic counsellor, a pedigree analysis, and a detailed post-test consultation to guide clinical management.
UAE Regulatory & Data Privacy Adherence
Your Data, Our Commitment: Compliance with UAE Law
- Data Protection: Fully compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Your genetic data is encrypted and never shared with third parties without your explicit written consent.
- Medical Liability & Consent: All clinical testing and patient consent protocols strictly adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring the highest standards of patient safety and ethical practice.
- Accreditation & Licensing: Our laboratory is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139) and operates under the direct licensure of the Dubai Health Authority (DHA License No: 1143).
- Convenient Logistics: VIP Mobile Phlebotomy & temperature-controlled home collection is available daily from 8 AM to 11 PM. For billing inquiries or appointment scheduling, contact us on WhatsApp at +971 54 548 8731.
Clinical & Logistical Metadata
| Test Name | DSPP Gene Dentin Dysplasia Type 2 NGS Genetic Test |
| Price (AED) | 2,800 AED (Inclusive of VAT) |
| Turnaround Time | 10 โ 14 Business Days (3 โ 4 Weeks) |
| Sample Type / Matrix | Whole Blood (EDTA), Extracted DNA, or FTA Card |
| Methodology Used | Next-Generation Sequencing (NGS) โ Illumina Platform |
| ICD-10-CM Code | K00.5 (Hereditary opalescent dentin / Dentin dysplasia) |
| LOINC Code | 81335-2 (Hereditary dentin disorder NGS panel) |
| DHA Facility License & Lab Address | DHA License No: 1143 | DNA Labs UAE, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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