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Test Price

2,800 AED

✅ Home Collection Available

DSP Gene (Skin Fragility-Woolly Hair Syndrome) Genetic Test in UAE | 2,800 AED | DHA Licensed

Executive Summary & Core Metrics

  • Diagnostic Accuracy: 99.9% sensitivity using massively parallel NGS at an ISO 9001:2015 certified laboratory.
  • VIP Mobile Phlebotomy & Cold-Chain Home Collection: Available daily from 8 AM to 11 PM across Dubai and the Northern Emirates.
  • Post-Test Genetic Counseling: Telephone consultation with a specialist to interpret your report and outline management steps.
  • Insurance Verification: Confirm coverage via WhatsApp +971 54 548 8731 – accepted by all major insurers.

Test Overview & Methodology

This NGS-based genetic test sequences the entire DSP gene to definitively diagnose skin fragility-woolly hair syndrome, a rare ectodermal dysplasia with significant cardiac implications. Performed under DHA regulatory standards, the test provides dermatologists and clinical geneticists with actionable data for patient management, including surveillance for arrhythmogenic cardiomyopathy.

Feature DNA Labs UAE – NGS Closest Alternative (Sanger Sequencing)
TechnologyMassively Parallel NGS – Full DSP gene coverageTargeted single-exon sequencing
Diagnostic Sensitivity99.9% (detects all variant types, including deep intronic)~85% for point mutations only
Turnaround Time3–4 Weeks6–8 Weeks
AccreditationISO 9001:2015 & DHA Facility License 1143Varies by laboratory
Price2,800 AED2,200–3,500 AED

Physician Insight & Safety Protocols

“A positive DSP mutation confirms the clinical diagnosis but must be interpreted alongside the full phenotype — particularly a cardiology assessment for arrhythmogenic cardiomyopathy. This test is one component of a comprehensive workup; never rely on genetic data in isolation. Our reports are clinically correlated and include actionable recommendations for the managing physician.”

— Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403

Advisory Notice

Do not discontinue any prescribed medication or modify your treatment regimen based solely on this genetic result without direct consultation with your treating physician. Genetic findings require clinical correlation and should never replace professional medical advice.

Exclusion Criteria & Red Flags

  • Recent blood transfusion or bone marrow transplant (may interfere with DNA source).
  • Uncontrolled bleeding disorder — consult your physician before sample collection.
  • Minors: Genetic testing requires explicit consent from a legal guardian and pre-test genetic counseling as per UAE regulatory frameworks.
  • Emergency Red Flags: If you experience sudden chest pain, fainting episodes, or severe palpitations before or after testing, seek immediate emergency care — these may indicate cardiac involvement in DSP-related syndromes.

Patient FAQ & Clinical Guidance

1. What exactly does this test detect?

This test sequences the entire DSP gene to identify mutations linked to skin fragility, woolly hair, and potentially life-threatening cardiomyopathy. NGS technology enables high-resolution detection of single nucleotide variants, insertions/deletions, and copy number abnormalities that conventional methods often miss.

2. Who should consider undergoing this genetic test?

Individuals with suggestive skin and hair abnormalities, a family history of the condition, or unexplained cardiomyopathy should pursue testing alongside genetic counseling. Early diagnosis guides surveillance for cardiac complications and informs family planning — pediatric patients particularly benefit from early monitoring.

3. How is the sample collected and what is the turnaround time?

A simple blood draw or DNA sample is collected by a certified phlebotomist at your home or in our facility within 24 hours of booking. Results are available in 3–4 weeks. The home visit follows temperature-controlled cold-chain protocols, and the entire process is conducted under DHA Facility License 1143.

4. What are the cardiac implications of a DSP mutation?

Mutations in the DSP gene are associated with arrhythmogenic cardiomyopathy, a condition that can lead to heart rhythm abnormalities and sudden cardiac arrest. A positive genetic result warrants a thorough cardiology evaluation, including ECG, echocardiogram, and possibly Holter monitoring, even in the absence of symptoms.

UAE Regulatory & Data Privacy Adherence

Regulatory Compliance: This service adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability.

DHA Facility License: 1143 | ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) | Corporate Lab: DNA Labs UAE | WhatsApp: +971 54 548 8731

Clinical & Logistical Metadata

Test Name DSP Gene (Skin Fragility-Woolly Hair Syndrome) Genetic Test
Price (AED) 2,800
Turnaround Time 3–4 Weeks
Sample Type / Matrix Whole Blood / DNA (Peripheral Venipuncture or FTA Card)
Methodology Used Next-Generation Sequencing (NGS) – Full Gene Coverage
ICD-10-CM Code Q84.2, Q82.8
LOINC Code 81247-9
DHA Facility License & Laboratory Address License 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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