Test Price
2,800 AED✅ Home Collection Available
DMP1 Gene Autosomal Recessive Hypophosphatemic Rickets Type 1 (ARHR1) Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل الجين DMP1 للكشف عن الكساح الناقص الفوسفات الوراثي المتنحي من النوع الأول (ARHR1) بتقنية تسلسل الجيل التالي في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary | ملخص تنفيذي
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: Hospital-Grade Home Collection with ISO Certified Cold-Chain & VIP Mobile Phlebotomy (8 AM–11 PM).
- Clinical Guidance: Post-Test Telephonic Clinical Guidance for Result Interpretation by DHA-Licensed Specialists.
- Insurance & Billing: Direct Billing Verification via WhatsApp +971 54 548 8731.
Strictly aligned with UAE Federal Decree-Law No. 41 of 2024 (Art. 87), CDS Law 2026 (Minor Protection), and UAE PDPL. ISO 9001:2015 Certified Facility License: 9834453.
Overview
This Genetic Test analyzes the entire DMP1 gene to detect pathogenic variants responsible for autosomal recessive hypophosphatemic rickets type 1 (ARHR1), a rare hereditary disorder of phosphate regulation causing severe bone deformities and short stature. يُعد هذا الفحص الجيني الشامل أداة تشخيصية دقيقة لتحديد الطفرات المسببة للمرض، مما يسمح بعلاج مبكر يركز على تعويض الفوسفات وفيتامين د النشط.
| Feature | Our DMP1 NGS Test | Sanger Sequencing (Alternative) |
|---|---|---|
| Gene Coverage | Full coding region, splice sites, and deep intronic regions | Selected exons only |
| Sensitivity for Rare Variants | >99.9% detection of known and novel mutations | ~95% limited to predefined regions |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks |
| Cost (AED) | 2800 | 2500–3500 |
Physician Insight & Safety Protocol
“Dear patient, as a Consultant Clinical Pathologist, I want to reassure you that this genetic test provides clarity about your bone health—but it must be interpreted alongside your full clinical picture, including serum phosphate, FGF23, and skeletal X-rays. Please remember that a genetic result is a piece of the puzzle, not a stand-alone verdict; our team is here to guide you through every step. Your health journey is unique, and we are committed to supporting you with precision and empathy.”
— Dr. Prabhakar Reddy, DHA License: 61713011
Medication Warning:
Do not discontinue or adjust any prescribed medication (including phosphate supplements or active vitamin D) without consulting your treating physician. Abrupt changes may trigger severe metabolic imbalances.
Safety Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Recent blood transfusion (within 4 weeks) may compromise DNA integrity; severe anemia that contraindicates venipuncture; inability to provide informed consent (parent/guardian for minors).
- ER Red Flags – seek immediate medical attention if you experience: acute bone pain or new fractures, tetany or muscle spasms (sign of hypocalcemia), severe chest wall deformity causing breathing difficulty, or sudden visual changes.
Patient FAQ & Clinical Guidance
1. What is the DMP1 gene NGS test and why do I need it?
This test sequences the entire DMP1 gene to identify disease-causing mutations for autosomal recessive hypophosphatemic rickets, enabling accurate diagnosis and personalised treatment. It helps distinguish ARHR1 from other phosphate-wasting disorders and guides targeted therapy with phosphate and calcitriol. يساعد هذا التحليل في تأكيد التشخيص وتمييزه عن الأمراض المشابهة، مما يمكّن الطبيب من وضع خطة علاجية دقيقة تعتمد على تعويض الفوسفات وفيتامين د.
2. How should I prepare for the DMP1 gene and what sample is required?
A genetic counselling session to draw a pedigree chart is mandatory, along with providing complete clinical history of the affected individual. We accept blood (collected by our certified phlebotomist), extracted DNA, or a single drop of blood on an FTA card. No fasting or medication changes are required, but please inform us about any recent blood transfusions. يجب حضور جلسة استشارة وراثية لرسم شجرة العائلة وتقديم التاريخ السريري المفصل للمريض، كما نقبل عينة دم كاملة أو حمض نووي مستخلص أو بقعة دم على بطاقة FTA.
3. Will my genetic data be kept confidential and what do the results mean?
Your genetic information is protected under UAE Personal Data Protection Law (PDPL) and processed exclusively in our ISO-certified facility. A positive result indicates the presence of a DMP1 mutation, confirming ARHR1, which helps tailor phosphate dosing and long-term monitoring. A negative result may necessitate evaluation for other hypophosphatemic disorders. All results are interpreted by a DHA-licensed clinical geneticist. جميع البيانات الجينية محمية بموجب قانون حماية البيانات الشخصية الإماراتي، ويتم تفسير النتائج من قبل أخصائي وراثة سريرية مرخص من هيئة الصحة بدبي لضمان الدقة والسرية التامة.
Methodology: Next Generation Sequencing (NGS) with ML-aligned variant interpretation. ICD-10-CM: E83.31 (Familial hypophosphatemic rickets), Z13.79 (Encounter for screening for genetic disease), Z82.79 (Family history of other congenital malformations and chromosomal abnormalities). LOINC: 79692-0 (DMP1 gene full mutation analysis).
Primary Specialists: Consultant Medical Geneticist, Pediatric Endocrinologist (Metabolic Bone Disease Specialist), Orthopedic Surgeon.
Home Collection Hours: 8 AM – 11 PM, 7 days a week. For assistance, WhatsApp +971 54 548 8731.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians