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Test Price

2,800 AED

✅ Home Collection Available

CPT2 Gene Carnitine Palmitoyltransferase II Deficiency (Lethal Neonatal) NGS Genetic Test in UAE

Executive Summary & Core Metrics

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 accredited NGS pipeline with orthogonal confirmation.
  • Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy – no clinic visit needed.
  • Clinical Guidance: Telephone-based post-test clinical interpretation and genetic counselling by DHA-licensed specialists.
  • Insurance Assistance: Direct Billing Verification via WhatsApp +971 54 548 8731. We handle the paperwork.

Test Overview & Methodology

The CPT2 NGS test delivers definitive molecular diagnosis within 3–4 weeks, enabling immediate metabolic management and family genetic counseling.

Feature Our CPT2 NGS Test Closest Alternative (Single-gene Sanger / Targeted Panel)
Methodology Full gene NGS with CNV analysis & orthogonal confirmation Sanger sequencing limited to known hotspots; may miss deep intronic/regulatory variants
Diagnostic Sensitivity 99.9% (with clinical correlation) ~85-90% for common mutations only
Turnaround Time 3-4 Weeks 2-4 Weeks (limited scope)
Sample Flexibility Whole Blood, Extracted DNA, Dried Blood Spot on FTA Card Often requires fresh blood; FTA card not accepted
Regulatory Compliance ISO 9001:2015, UAE PDPL, Health ICT Law 2019 Variable; may lack full UAE clinical licensing

Physician Insight & Safety Protocols

“As a Consultant in Medical Genetics, I understand the urgency in diagnosing lethal neonatal metabolic disorders. This comprehensive NGS analysis of the CPT2 gene provides a precise molecular diagnosis that guides immediate life-saving interventions and informs family planning. However, clinical correlation with biochemical and metabolic markers remains essential.” — Lina Osama Zaki Quteineh (DHA: 9294403)

Medication Warning: Do not discontinue prescribed medication or supplements without consulting your treating physician. Inform the phlebotomist of all current medications; some can interfere with DNA extraction and quality.

Exclusion Criteria & Safety Red Flags

  • Exclusion: Individuals who have undergone allogeneic bone marrow transplantation within the last 6 weeks, or recent whole blood transfusion, as donor DNA may contaminate the sample.
  • Exclusion: Patients on leukocyte-reduced blood products; collected DNA yield may be insufficient.
  • Emergency Red Flags: If the newborn exhibits seizures, severe hypoglycaemia, hypotonia, cardiomyopathy, or respiratory distress, seek immediate emergency medical care. Do not wait for test results.

Patient FAQ & Clinical Guidance

1. Why does my neonate need a CPT2 genetic test so urgently?

This test rapidly confirms or excludes lethal neonatal CPT2 deficiency, a metabolic crisis that can cause sudden death if undetected and untreated. The NGS analysis of the full CPT2 gene detects pathogenic variants responsible for life-threatening hypoglycaemia and cardiac complications, enabling emergency metabolic support and a clear medical management plan within hours of result interpretation.

2. How reliable is the CPT2 deficiency genetic test for newborns?

Our ISO-accredited NGS test offers 99.9% diagnostic sensitivity for CPT2 gene mutations when paired with biochemical and clinical findings. The test analyzes all coding exons, flanking intronic regions, and copy number variations. A positive result is definitive; a negative result in a symptomatic neonate warrants further metabolic workup for other fatty acid oxidation disorders.

3. What do the results mean for my family and future pregnancies?

A positive CPT2 result confirms autosomal recessive inheritance, meaning both parents are obligate carriers; genetic counseling can guide reproductive choices. Carrier testing for siblings and relatives is available, and prenatal/preimplantation genetic diagnosis can be offered. Identification of the familial mutation allows precise family planning and early management of subsequent births.

UAE Regulatory & Data Privacy Adherence

Your data is protected under UAE Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Our DHA-licensed laboratory adheres to strict confidentiality and security protocols.

Clinical & Logistical Metadata

Test Name CPT2 Gene Carnitine Palmitoyltransferase II Deficiency (Lethal Neonatal) NGS Genetic Test
Price (AED) 2,800 AED
Turnaround Time 3–4 Weeks
Sample Type / Matrix Whole Blood (Venous), Extracted DNA, Dried Blood Spot on FTA Card
Methodology Used Next-Generation Sequencing (NGS) with CNV analysis and orthogonal confirmation
ICD-10-CM Code E71.312
LOINC Code 101675-7
DHA Facility License & Laboratory Address DHA Facility License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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