Test Price
2,800 AED✅ Home Collection Available
CHRM3 Gene (Prune Belly Syndrome) Genetic Test in UAE – 2,800 AED
Executive Summary & Core Metrics
Premium Logistics: Complimentary VIP mobile phlebotomy and temperature‑controlled cold‑chain home collection across UAE (daily 8 AM – 11 PM) for whole blood, extracted DNA, or FTA card samples.
Clinical Guidance: Complimentary post‑test telephonic clinical correlation session with a DHA‑licensed genetic counsellor to interpret results within the patient’s pedigree.
Insurance & Billing: Direct insurance verification and pre‑approval via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
This advanced genetic test interrogates the entire coding region of the CHRM3 gene using Next Generation Sequencing (NGS), enabling precise family planning and paediatric surgical planning. The workflow covers all 15 exons and flanking intronic regions with a validated clinical bioinformatics pipeline that filters out benign polymorphisms, reporting only pathogenic or likely pathogenic variants according to ACMG guidelines.
In parallel, the service provides a clinical history review, pedigree charting, and a rapid 3–4 week turnaround, unlike fragmented overseas offerings that lack local follow‑up.
| Feature | Our Test (DHA‑Licensed) | Closest Alternative |
|---|---|---|
| Precision | NGS full gene sequencing, >99.9% SNV/indel detection | Sanger sequencing (limited to few exons) |
| Methodology | LC‑MS/MS validated NGS library prep + bioinformatics | Research‑grade capture panels |
| Turnaround | 3–4 weeks with genetic counselling | 6–8 weeks, no local counselling |
Physician Insight & Safety Protocols
“As a clinical geneticist, I emphasise that the CHRM3 gene test is a piece of a larger diagnostic puzzle. A negative result does not exclude the syndrome if clinical features are classic; conversely, a pathogenic variant should be correlated with multidisciplinary imaging and urodynamic studies before surgical intervention. Always involve a board‑certified geneticist and paediatric surgeon early in the care pathway.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
⚕️ Safety Advisory: Do not discontinue any prescribed medication (e.g., anticholinergics, diuretics, or antihypertensives) without consulting your managing physician, even in preparation for this test. The test requires only a standard blood draw; no medication alteration is necessary.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Unable to provide blood or extracted DNA (severe haemophilia A with inhibitor, active systemic infection).
- Exclusion: Patient or legal guardian cannot give informed consent as per UAE Federal Decree‑Law No. 4 of 2016 on Medical Liability.
- Exclusion: Minors (under 18) without a court‑appointed guardian – genetic testing on minors strictly requires authorized consent.
- ER Red Flag: Acute respiratory distress or severe abdominal distension in the patient – proceed directly to emergency department, do not delay for test collection.
- ER Red Flag: New‑onset anuria or urosepsis – urgent urological evaluation takes precedence.
Patient FAQ & Clinical Guidance
1. What exactly does this CHRM3 gene test detect?
This test identifies single nucleotide variants, insertions, deletions, and copy number changes within the CHRM3 gene that cause Prune Belly Syndrome. Our NGS workflow covers all 15 exons and flanking intronic regions with a validated clinical bioinformatics pipeline that filters out benign polymorphisms, reporting only pathogenic or likely pathogenic variants according to ACMG guidelines.
2. How should I prepare for the test and what does the home collection involve?
No fasting or medication changes are required; simply provide a small venous blood sample, or alternatively, one drop of blood on an FTA card. A DHA‑licensed phlebotomist arrives at your home between 8 AM and 11 PM with a temperature‑controlled transport box. The sample is immediately triple‑checked against your Emirates ID or passport, then shipped under chain‑of‑custody to our ISO‑certified laboratory.
3. Is the CHRM3 gene test available for infants and does it require special consent?
Yes, the test is available for infants but UAE law (Federal Decree‑Law No. 4 of 2016 on Medical Liability) requires the legal guardian’s informed consent along with a medical report establishing clinical necessity. Sample collection is performed via heel prick or a gentle venous draw. Pre‑test genetic counselling is provided to assess syndrome risk and plan surgical management for the newborn.
UAE Regulatory & Data Privacy Adherence
Data Security & Privacy: This service adheres strictly to Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted, access‑controlled, and processed under explicit patient consent.
Clinical Safety: Sample collection and reporting follow the requirements of Federal Decree‑Law No. 4 of 2016 on Medical Liability, ensuring patient safety, informed consent, and medico‑legal accountability.
Clinical & Logistical Metadata
| Test Name | CHRM3 Gene (Prune Belly Syndrome) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Whole Blood, Extracted DNA, or FTA Card |
| Methodology Used | Next Generation Sequencing (NGS) – Full Gene Sequencing |
| ICD-10-CM Code | Q79.4 |
| LOINC Code | 86654-1 |
| DHA Facility License & Laboratory Address | License No. 1143 · Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians