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Test Price

2,800 AED

✅ Home Collection Available

CETP Gene Hyperalphalipoproteinemia Genetic Test in UAE – 2,800 AED

Executive Summary & Core Metrics

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing and Targeted NGS with Sanger Confirmation.
  • Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily 8 AM – 11 PM).
  • Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation with a senior genetic counsellor.
  • Insurance: Direct Billing Verification via WhatsApp: +971 54 548 8731

Test Overview & Methodology

The CETP gene encodes cholesteryl ester transfer protein, a key regulator of high-density lipoprotein (HDL) metabolism. Pathogenic variants in CETP can cause familial hyperalphalipoproteinemia (elevated HDL-C), a condition linked to altered cardiovascular risk profiles. This targeted next-generation sequencing (NGS) test detects single nucleotide variants, insertions, deletions, and splice-site mutations across the entire coding region and flanking intronic boundaries of the CETP gene, with all clinically significant findings confirmed via Sanger sequencing.

Feature Our Test – CETP NGS Closest Alternative
Methodology Targeted NGS + Sanger confirmation Sanger sequencing only
Precision 99.9% diagnostic sensitivity ~95% sensitivity, may miss deep intronic variants
Turnaround Time 3 – 4 Weeks (guaranteed) 4 – 6 Weeks
Genetic Counseling Included pre- and post-test Often separate
UAE Regulatory Compliance Full DHA / MOHAP & PDPL adherence Variable

Physician Insight & Safety Protocols

“Interpreting CETP gene variants demands a thorough evaluation of lipid metabolism and cardiovascular risk stratification. I encourage patients to view this genetic data as one element of a complete clinical picture that includes their lipid panel, family history, and lifestyle patterns. Safe, personalized decisions arise when molecular findings are integrated with expert medical guidance.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Clinical Advisory – Medication Continuity

Do not alter or discontinue any prescribed lipid-lowering therapy (statins, fibrates, niacin, or PCSK9 inhibitors) without direct supervision from your treating physician. Genetic test results provide risk information and are not standalone directives for medication changes. All therapeutic adjustments require clinical correlation and monitoring.

Safety Exclusion Criteria & Emergency Red Flags

Exclusion Criteria – Do Not Proceed with Sample Collection

  • Recent blood transfusion (<14 days)
  • Active systemic infection or fever >38°C
  • Known severe coagulopathy (INR >1.5)
  • Inability to provide an adequate blood or saliva specimen

Emergency Red Flags – Seek Immediate Medical Attention

  • New onset severe crushing chest pain or pressure
  • Sudden shortness of breath or loss of consciousness
  • Acute confusion or focal neurological deficit
  • Palpitations with dizziness or syncope

This test assesses genetic predisposition; it does not replace emergency clinical evaluation.

Patient FAQ & Clinical Guidance

1. What does a positive CETP mutation mean for my overall health?

A positive CETP mutation indicates a genetic predisposition to elevated high-density lipoprotein cholesterol (HDL-C). While high HDL-C has traditionally been viewed as protective, certain CETP variants can produce very elevated levels that may, in some contexts, be associated with altered cardiovascular risk. Your physician will integrate this finding with your complete lipid profile, family history, and lifestyle factors to provide a personalized assessment. This result must never be interpreted in isolation.

2. How should I prepare for the blood or DNA sample collection?

No special preparation is required for the genetic sample. DNA remains stable regardless of fasting or medication use. You may provide a peripheral whole blood sample through venipuncture, an extracted DNA specimen, or a single drop of blood on an FTA card. Our mobile phlebotomist will coordinate the entire collection during your scheduled home visit. Please inform us of any anticoagulant medications beforehand to ensure safe collection.

3. Is this genetic test covered by health insurance in the UAE?

Many UAE health insurers cover genetic testing when ordered by a specialist and supported by clinical justification, though coverage terms vary by policy. We offer direct billing verification — send your insurance card via WhatsApp to +971 54 548 8731 and our team will confirm eligibility within hours. For self-pay patients, the test is priced at 2,800 AED, inclusive of pre- and post-test genetic counseling.

UAE Regulatory & Data Privacy Adherence

Legal Compliance Framework

All genetic testing and personal data processing are conducted in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical laboratory safety and patient consent procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. Our facility is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139) and all NGS platforms undergo routine validation against LC-MS/MS and Sanger reference standards.

Clinical & Logistical Metadata

Test Name CETP Gene Hyperalphalipoproteinemia Genetic Test
Price (AED) 2,800 AED
Turnaround Time 3–4 Weeks
Sample Type / Matrix Peripheral Whole Blood, Saliva, or FTA Card Spot
Methodology Used Targeted NGS with Sanger Confirmation
ICD-10-CM Code E78.8
LOINC Code 21776-5
DHA Facility License & Laboratory Address License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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All reports reviewed by DHA-Certified physicians