Test Price
2,800 AED✅ Home Collection Available
BOLA3 Gene Multiple Mitochondrial Dysfunctions Syndrome Type 2 (MMDS2) Genetic Test in UAE | AED 2,800 | DHA Licensed
Executive Summary & Core Metrics
Achieve diagnostic clarity with our NGS-based BOLA3 genetic analysis, delivering 99.9% analytical sensitivity under ISO 9001:2015 certified processing. Benefit from VIP mobile phlebotomy with temperature-controlled cold-chain home collection (daily 8 AM – 11 PM), a dedicated telephonic post-test consultation, and rapid insurance verification via WhatsApp +971 54 548 8731. Your journey to precise neurological answers begins with a simple blood sample.
Test Overview & Methodology
The BOLA3 NGS test sequences the entire coding region (all exons ±20 bp intronic boundaries) to identify pathogenic variants underlying Multiple Mitochondrial Dysfunctions Syndrome Type 2 (MMDS2), a severe autosomal recessive neurodegenerative disorder. It enables definitive diagnosis, carrier screening, and informed family planning—critical for at-risk UAE families.
| Feature | Our BOLA3 NGS Test | Closest Alternative |
|---|---|---|
| Methodology | Full-gene Next Generation Sequencing (NGS) | Targeted Sanger sequencing (single exon) |
| Gene Coverage | 100% coding exons ± 20 bp intronic boundaries | Limited; misses deep intronic/regulatory variants |
| Analytical Sensitivity | >99.9% | ≈99% |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
| Price | AED 2,800 | AED 3,500 |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA Registration ID: 9294403), affirms: “This advanced genomic test provides definitive molecular diagnosis for families facing the devastating trajectory of Multiple Mitochondrial Dysfunctions Syndrome Type 2. It offers clarity for prognosis, guides reproductive planning, and must be interpreted in conjunction with biochemical and clinical findings. A negative result does not rule out mitochondrial disease if clinical suspicion remains high.”
⚠️ Medication Advisory
Never discontinue or modify prescribed medications, including anticonvulsants or mitochondrial support therapies, without explicit guidance from your treating neurologist or metabolic specialist.
⛔ Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Inability to provide informed consent; testing of minors requires mandatory parental/guardian consent and presence per UAE Federal Law No. 2 of 2019 on health information use. Pregnant individuals may proceed but must undergo pre- and post-test genetic counselling.
- Emergency Red Flags: If you experience new-onset seizures, loss of consciousness, or stroke-like episodes during the test waiting period, immediately visit the nearest emergency department. Inform the attending physician about this pending genetic investigation to prevent diagnostic delay.
- All genetic data is protected under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and processed in accordance with Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety follows Federal Decree-Law No. 4 of 2016 on Medical Liability.
Patient FAQ & Clinical Guidance
1. What conditions does the BOLA3 genetic test diagnose?
The test primarily diagnoses Multiple Mitochondrial Dysfunctions Syndrome Type 2 (MMDS2), a fatal infantile mitochondriopathy causing severe neurological regression. It also identifies heterozygous carriers and supports differential diagnosis of mitochondrial encephalomyopathies when other genetic panels are inconclusive.
2. How is the sample collected and is home service available?
A simple peripheral blood sample (2–3 mL EDTA whole blood or FTA card) is required. Our VIP mobile phlebotomy team provides temperature-controlled cold-chain home collection across all UAE emirates daily from 8 AM to 11 PM, ensuring specimen integrity.
3. How long do results take and how will I receive them?
Results are ready within 3–4 weeks and securely shared via encrypted patient portal with a detailed clinical report. A board-certified genetic counsellor or medical geneticist will schedule a tele-consultation to explain findings and recommend next steps.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance & Data Protection
- Data Privacy: All genetic and personal data processed under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Medical Liability: Clinical procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Accreditation: Laboratory processes ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139). DHA Facility License 1143.
Clinical & Logistical Metadata
| Test Name | BOLA3 Gene Sequencing (Multiple Mitochondrial Dysfunctions Syndrome Type 2) |
| Price (AED) | AED 2,800 |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral whole blood (EDTA) or FTA card; VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily 8 AM – 11 PM) |
| Methodology Used | Next Generation Sequencing (NGS) – full gene coding region ± 20 bp intronic boundaries |
| ICD-10-CM Code | G31.89 (Other specified degenerative diseases of nervous system) |
| LOINC Code | 89588-6 (BOLA3 gene full sequencing) |
| DHA Facility License & Address | DHA Facility License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
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ISMS 27001:2022
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All reports reviewed by DHA-Certified physicians